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Genetics

D-Index
87
Citations
38557
World Ranking
1193
National Ranking
572

Medicine

D-Index
87
Citations
38933
World Ranking
13432
National Ranking
6832

Overview

John D. Carpten is affiliated with the University of Southern California in the United States. Their research spans multiple fields of study, primarily focused on Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader areas, their work frequently intersects subfields such as Cancer Research, Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, and Genetics.

The researcher's publication topics highlight a concentration on Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Prostate Cancer Treatment and Research, Ferroptosis and cancer prognosis, Molecular Biology Techniques and Applications, Genetic factors in colorectal cancer, and BRCA gene mutations in cancer.

Published work includes several notable papers:

  • "African Ancestry-Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent" (2022) in Cancer Discovery
  • "Spatial Transcriptomic Analysis of a Diverse Patient Cohort Reveals a Conserved Architecture in Triple-Negative Breast Cancer" (2022) in Cancer Research
  • "Single-cell sequencing of genomic DNA resolves sub-clonal heterogeneity in a melanoma cell line" (2020) in Communications Biology
  • "Applicability of spatial transcriptional profiling to cancer research" (2021) in Molecular Cell
  • "A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry" (2020) in European Urology

John D. Carpten frequently co-authors with researchers such as David W. Craig, Mariana C. Stern, Rania Bassiouni, Michelle L. Churchman, and Martin D. McCarter. This collaboration pattern supports research efforts across cancer-related fields and molecular biology.

Their publications have appeared regularly in prominent venues including:

  • Cancer Research
  • Cancer Epidemiology Biomarkers & Prevention
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology

Best Publications

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

    Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha

  • Molecular classification of cutaneous malignant melanoma by gene expression profiling

    M. Bittner;P.S.J. Meltzer;Y.D. Chen;Y. Jiang

  • Initial genome sequencing and analysis of multiple myeloma

    Michael A. Chapman;Michael S. Lawrence;Jonathan J. Keats;Kristian Cibulskis

  • Modulation of non-templated nucleotide addition by Taq DNA polymerase: primer modifications that facilitate genotyping.

    Michael J. Brownstein;John D. Carpten;Jeffrey R. Smith

  • A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

    John D. Carpten;Andrew L. Faber;Candice Horn;Gregory P. Donoho

  • Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

    Jonathan J. Keats;Rafael Fonseca;Marta Chesi;Roelandt Schop

  • Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search

    Jeffrey R. Smith;Diha Freije;John D. Carpten;Henrik Grönberg;Henrik Grönberg

  • Germline Mutations in HOXB13 and Prostate-Cancer Risk

    Patrick C. Walsh

  • HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

    J.D. Carpten;C.M. Robbins;A. Villablanca;L. Forsberg

  • Cumulative Association of Five Genetic Variants with Prostate Cancer

    S. Lilly Zheng;Jielin Sun;Fredrik Wiklund;Shelly Smith

  • Clonal competition with alternating dominance in multiple myeloma

    Jonathan J. Keats;Marta Chesi;Jan B. Egan;Victoria M. Garbitt

  • Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

    Rebecca J. Leary;Mark Sausen;Isaac Kinde;Nickolas Papadopoulos

  • Translating RNA sequencing into clinical diagnostics: opportunities and challenges

    Sara A. Byron;Kendall R. Van Keuren-Jensen;David M. Engelthaler;John D. Carpten

  • Germline mutations in the ribonuclease L gene in families showing linkage with HPC1.

    J. Carpten;N. Nupponen;S. Isaacs;R. Sood

  • The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth

    David K. Rhee;Jose Marcelino;MacArthur Baker;Yaoqin Gong

  • Evidence for a prostate cancer susceptibility locus on the X chromosome.

    Jianfeng Xu;Deborah Meyers;Diha Freije;Sarah Isaacs

  • Somatic and Germ-Line Mutations of the HRPT2 Gene in Sporadic Parathyroid Carcinoma

    Trisha M. Shattuck;Stiina Välimäki;Takao Obara;Randall D. Gaz

  • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

    Ali Amin Al Olama;Zsofia Kote-Jarai;Sonja I. Berndt;David V. Conti

  • Molecular classification of cutaneous malignant melanoma by gene expression profiling

    M. Bittner;P. Meltzer;Y. Chen;Y. Jiang

  • Comment on: Cumulative Association of Five Genetic Variants with Prostate Cancer

    S. L. Zheng;J. Sun;F. Wiklund;S. Smith

Frequent Co-Authors

David Craig
David Craig University of Southern California
William B. Isaacs
William B. Isaacs Johns Hopkins University
Jianfeng Xu
Jianfeng Xu Arkansas State University
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute
Henrik Grönberg
Henrik Grönberg Karolinska Institute
Rafael Fonseca
Rafael Fonseca Mayo Clinic
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Joan E. Bailey-Wilson
Joan E. Bailey-Wilson National Institutes of Health
Patrick C. Walsh
Patrick C. Walsh Johns Hopkins University
Esther M. John
Esther M. John Stanford University

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