John D. Carpten mainly investigates Genetics, Prostate cancer, Gene, Cancer research and Germline mutation. Prostate cancer is a subfield of Cancer that John D. Carpten investigates. John D. Carpten works mostly in the field of Gene, limiting it down to topics relating to Multiple myeloma and, in certain cases, Somatic evolution in cancer, NF-κB, Deubiquitinating Enzyme CYLD, TRAF3 and Regulation of gene expression.
His research investigates the link between Cancer research and topics such as Immunology that cross with problems in Cutaneous melanoma, Melanoma, Vasculogenic mimicry, Phenotype and Neoplasm. His work carried out in the field of Germline mutation brings together such families of science as Endocrinology, RNASEL Gene and Loss of heterozygosity. His work is dedicated to discovering how Prostate, Oncology are connected with Rectal examination and other disciplines.
His primary areas of investigation include Genetics, Prostate cancer, Internal medicine, Oncology and Cancer. His is doing research in Gene, Single-nucleotide polymorphism, Locus, Genetic linkage and Genotype, both of which are found in Genetics. The Prostate cancer study combines topics in areas such as Odds ratio, Genome-wide association study, Prostate, Allele and Genetic association.
His work in Oncology tackles topics such as Multiple myeloma which are related to areas like Comparative genomic hybridization. John D. Carpten has included themes like Cancer research, Disease, Pathology and Bioinformatics in his Cancer study. The concepts of his Cancer research study are interwoven with issues in Mutation, Cell culture, Transcriptome and Immunology.
John D. Carpten mainly focuses on Oncology, Internal medicine, Cancer research, Prostate cancer and Cancer. His Oncology research also works with subjects such as
The various areas that he examines in his Cancer research study include Cell culture, Immune system, Epigenetics, Gene and Triple-negative breast cancer. His Prostate cancer research is multidisciplinary, incorporating perspectives in Genome-wide association study, Disease, Familial clustering, Circulating tumor cell and Liquid biopsy. His Genotype research is within the category of Genetics.
John D. Carpten spends much of his time researching Internal medicine, Oncology, Exome, Exome sequencing and Genetics. John D. Carpten works mostly in the field of Internal medicine, limiting it down to topics relating to Copy-number variation and, in certain cases, CpG Island Methylator Phenotype, Colorectal cancer, Microsatellite, Microsatellite instability and Circulating tumor cell, as a part of the same area of interest. In Exome, John D. Carpten works on issues like Germline mutation, which are connected to Mutation frequency and Malignancy.
His research investigates the connection between Exome sequencing and topics such as Genomics that intersect with problems in Single-nucleotide polymorphism, DNA sequencing, In silico, SNP and Precision medicine. His study ties his expertise on Multiple myeloma together with the subject of Genetics. His Prostate cancer study combines topics from a wide range of disciplines, such as Odds ratio, Genome-wide association study, Bioinformatics, Gene expression profiling and Mitochondrion.
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Molecular classification of cutaneous malignant melanoma by gene expression profiling
M. Bittner;P.S.J. Meltzer;Y.D. Chen;Y. Jiang.
Nature (2000)
Modulation of non-templated nucleotide addition by Taq DNA polymerase: primer modifications that facilitate genotyping.
Michael J. Brownstein;John D. Carpten;Jeffrey R. Smith.
BioTechniques (1996)
Initial genome sequencing and analysis of multiple myeloma
Michael A. Chapman;Michael S. Lawrence;Jonathan J. Keats;Kristian Cibulskis.
Nature (2011)
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
John D. Carpten;Andrew L. Faber;Candice Horn;Gregory P. Donoho.
Nature (2007)
Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma
Jonathan J. Keats;Rafael Fonseca;Marta Chesi;Roelandt Schop.
Cancer Cell (2007)
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants
Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha.
American Journal of Human Genetics (2016)
Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search
Jeffrey R. Smith;Diha Freije;John D. Carpten;Henrik Grönberg;Henrik Grönberg.
Science (1996)
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome
J.D. Carpten;C.M. Robbins;A. Villablanca;L. Forsberg.
Nature Genetics (2002)
Cumulative Association of Five Genetic Variants with Prostate Cancer
S. Lilly Zheng;Jielin Sun;Fredrik Wiklund;Shelly Smith.
The New England Journal of Medicine (2008)
Clonal competition with alternating dominance in multiple myeloma
Jonathan J. Keats;Marta Chesi;Jan B. Egan;Victoria M. Garbitt.
Blood (2012)
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