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Biology and Biochemistry

D-Index
89
Citations
47794
World Ranking
2496
National Ranking
1313

Overview

Samie R. Jaffrey is affiliated with Cornell University in the United States and has a primary research focus in biochemistry, genetics, and molecular biology. Within this broad field, their work emphasizes molecular biology, cancer research, oncology, electrical and electronic engineering, and ecology.

The scientist's research explores a variety of topics, including:

  • RNA modifications and cancer
  • RNA research and splicing
  • RNA and protein synthesis mechanisms
  • Cancer-related gene regulation
  • Advanced biosensing and bioanalysis techniques
  • Cancer-related molecular mechanisms research
  • HVDC systems and fault protection

Frequent publication venues for Samie R. Jaffrey include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Nature Chemical Biology
  • PLoS Biology
  • Cell

Recent publications illustrate key areas of their research. Notable papers are:

  • "A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA," 2020, Cell
  • "The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells," 2020, Cancer Discovery
  • "Limits in the Detection of m6A Changes Using MeRIP/m6A-seq," 2020, Scientific Reports
  • "N6-Methyladenosine on mRNA Facilitates a Phase-Separated Nuclear Body That Suppresses Myeloid Leukemic Differentiation," 2021, Cancer Cell
  • "mTORC1 Promotes Cell Growth via m6A-Dependent mRNA Degradation," 2021, Molecular Cell

Collaboration forms a significant component of their work, with frequent co-authors including Aashiq H. Mirza, Jiahui Wu, Hui Xian Poh, Xing Li, and Jianheng Liu.

Best Publications

  • Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

    Kate D. Meyer;Yogesh Saletore;Paul Zumbo;Olivier Elemento

  • RNA Mimics of Green Fluorescent Protein

    Jeremy S. Paige;Karen Y. Wu;Samie R. Jaffrey

  • Reading, writing and erasing mRNA methylation.

    Sara Zaccara;Ryan J Ries;Samie R Jaffrey

  • 5′ UTR m6A Promotes Cap-Independent Translation

    Kate D. Meyer;Deepak P. Patil;Jun Zhou;Alexandra Zinoviev

  • Protein S-nitrosylation: a physiological signal for neuronal nitric oxide.

    Samie R. Jaffrey;Hediye Erdjument-Bromage;Christopher D. Ferris;Paul Tempst

  • m 6 A RNA methylation promotes XIST -mediated transcriptional repression

    Deepak P. Patil;Chun-Kan Chen;Brian F. Pickering;Amy Chow

  • Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

    Bastian Linder;Anya V Grozhik;Anthony O Olarerin-George;Cem Meydan

  • Dynamic m6A mRNA methylation directs translational control of heat shock response

    Jun Zhou;Ji Wan;Xiangwei Gao;Xingqian Zhang

  • The Biotin Switch Method for the Detection of S-Nitrosylated Proteins

    Samie R. Jaffrey;Solomon H. Snyder

  • The dynamic epitranscriptome: N6-methyladenosine and gene expression control

    Kate D. Meyer;Samie R. Jaffrey

  • The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

    Ly P Vu;Brian F Pickering;Yuanming Cheng;Sara Zaccara

  • Rethinking m6A Readers, Writers, and Erasers.

    Kate D. Meyer;Samie R. Jaffrey

  • Reversible methylation of m6Am in the 5′ cap controls mRNA stability

    Jan Mauer;Xiaobing Luo;Alexandre Blanjoie;Xinfu Jiao

  • PIN: An Associated Protein Inhibitor of Neuronal Nitric Oxide Synthase

    Samie R. Jaffrey;Solomon H. Snyder

  • Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution.

    Grigory S. Filonov;Jared D. Moon;Nina Svensen;Samie R. Jaffrey

  • Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling.

    Guoqiang Xu;Jeremy S Paige;Samie R Jaffrey

  • Haem oxygenase-1 prevents cell death by regulating cellular iron

    Christopher D. Ferris;Samie R. Jaffrey;Akira Sawa;Masaaki Takahashi

  • m 6 A enhances the phase separation potential of mRNA

    Ryan J. Ries;Sara Zaccara;Pierre Klein;Anthony Olarerin-George

  • A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.

    Sara Zaccara;Samie R. Jaffrey

  • Fluorescence Imaging of Cellular Metabolites with RNA

    Jeremy S. Paige;Thinh Nguyen-Duc;Wenjiao Song;Samie R. Jaffrey

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Christopher E. Mason
Christopher E. Mason Cornell University
Jean-Jacques Vasseur
Jean-Jacques Vasseur University of Montpellier
Anthony A. Sauve
Anthony A. Sauve Cornell University
Hyung Joon Kim
Hyung Joon Kim Kyungpook National University
Noo Li Jeon
Noo Li Jeon Seoul National University
Steven S. Gross
Steven S. Gross Cornell University
Olivier Elemento
Olivier Elemento Cornell University

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