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Immunology

D-Index
48
Citations
12418
World Ranking
4395
National Ranking
2

Overview

Kai Kisand is affiliated with the University of Tartu in Estonia and has contributed extensively to research within the fields of Medicine and Immunology and Microbiology. Their work encompasses a range of subfields including Immunology, Infectious Diseases, Genetics, Epidemiology, and Rheumatology. The scientist's research topics primarily focus on T-cell and B-cell Immunology, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Immune Cell Function and Interaction, Diabetes and associated disorders, Long-Term Effects of COVID-19, and Systemic Lupus Erythematosus Research.

Their publication record includes notable recent papers such as:

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19 (2020, Science)
  • A dynamic COVID-19 immune signature includes associations with poor prognosis (2020, Nature Medicine)
  • Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study (2021, The Lancet Regional Health - Europe)
  • Human genetic and immunological determinants of critical COVID-19 pneumonia (2022, Nature)
  • Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1 (2021, The Journal of Experimental Medicine)

Kisand's frequent coauthors include:

  • Pärt Peterson
  • Liis Haljasmägi
  • Liina Tserel
  • Filomeen Haerynck
  • Petter Brodin

The primary venues where Kisand has published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • Journal of Investigative Dermatology
  • Frontiers in Immunology
  • Nature Medicine

Best Publications

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • A dynamic COVID-19 immune signature includes associations with poor prognosis.

    Adam G. Laing;Anna Lorenc;Irene del Molino del Barrio;Irene del Molino del Barrio;Abhishek Das;Abhishek Das

  • Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

    Kai Kisand;Anette S. Bøe Wolff;Katarina Trebušak Podkrajšek;Liina Tserel

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study.

    Paul Naaber;Paul Naaber;Liina Tserel;Kadri Kangro;Epp Sepp

  • Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype.

    Julie Toubiana;Satoshi Okada;Satoshi Okada;Julia Hiller;Matias Oleastro

  • Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study

    Gillian I Rice;Gabriella M A Gm Forte;Marcin Szynkiewicz;Diana S Chase

  • AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

    Steffen Meyer;Martin Woodward;Christina Hertel;Philip Vlaicu

  • Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1.

    Paul Bastard;Paul Bastard;Paul Bastard;Elizaveta Orlova;Leila Sozaeva;Romain Lévy;Romain Lévy

  • The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

    Unknown

  • Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes.

    Liina Tserel;Raivo Kolde;Maia Limbach;Konstantin Tretyakov

  • MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4.

    Liina Tserel;Toomas Runnel;Kai Kisand;Maire Pihlap

  • Autoantibodies against type I IFNs in patients with critical influenza pneumonia

    Unknown

  • Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells.

    Silva Kasela;Kai Kisand;Liina Tserel;Epp Kaleviste

  • Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes

    Kai Kisand;Maire Link;Anette S. B. Wolff;Anthony Meager

  • Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: Clinical and pathogenetic implications

    Kai Kisand;Desa Lilic;Jean-Laurent Casanova;Jean-Laurent Casanova;Pärt Peterson

  • Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens

    Xiaoping Wang;Martti Laan;Rudolf Bichele;Kai Kisand

  • Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells

    Pietro Luigi Poliani;Kai Kisand;Veronica Marrella;Maria Ravanini

  • Modulation of Aire regulates the expression of tissue-restricted antigens.

    Vivian Kont;Martti Laan;Kai Kisand;Andres Merits

  • Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.

    Maia Limbach;Mario Saare;Liina Tserel;Kai Kisand

  • Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes

    Martti Laan;Kai Kisand;Vivian Kont;Kaidi Möll

  • Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: known and novel aspects of the syndrome

    Kai Kisand;Pärt Peterson

Frequent Co-Authors

Pärt Peterson
Pärt Peterson University of Tartu
Adrian Hayday
Adrian Hayday King's College London
Kai Krohn
Kai Krohn Tampere University
Eystein S. Husebye
Eystein S. Husebye University of Bergen
Raivo Uibo
Raivo Uibo University of Tartu
Annamari Ranki
Annamari Ranki University of Helsinki
Nick Willcox
Nick Willcox University of Oxford
Hamish S. Scott
Hamish S. Scott University of Adelaide
Lili Milani
Lili Milani University of Tartu

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