World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
49
Citations
11593
World Ranking
4533
National Ranking
43

Overview

Kai Krohn is affiliated with Tampere University in Finland, focusing on research within the fields of medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields including molecular biology, immunology, genetics, physiology, and rheumatology.

Their publications reveal a focus on immune system regulation, pluripotent stem cells, and genetic engineering techniques, particularly in relation to autoimmune and respiratory conditions.

Recent research topics covered by Krohn include:

  • Virus-based gene therapy research
  • Pluripotent stem cells research
  • CRISPR and genetic engineering
  • Asthma and respiratory diseases
  • Urticaria and related conditions
  • Adrenal hormones and disorders
  • T-cell and B-cell immunology

Their notable papers include:

  • "Generation and Characterization of iPS Cells Derived from APECED Patients for Gene Correction" (2022) published in Frontiers in Endocrinology
  • "Neutralizing natural anti-IL-17F autoantibodies protect Autoimmune Polyendocrine Syndrome Type 1 (APS-1) patients from asthma" (2020) published in Clinical Immunology
  • "A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification" (2024) published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Post-Covid-Syndrom als Schwerbehinderung" (2025) published in WzS Wege zur Sozialversicherung

Krohn frequently collaborates with other researchers, including Annamari Ranki, Eira Karvonen, Annika Hau, Martta Jokinen, and Sanna Edelman. The recurring affiliations highlight connections primarily within immunology and molecular biology research networks.

Publication venues where Krohn's work appears regularly include:

  • Frontiers in Endocrinology
  • Clinical Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • WzS Wege zur Sozialversicherung

The research outputs and collaboration networks reflect an emphasis on exploring immune system mechanisms, gene correction approaches, and disease-specific investigations such as autoimmune polyendocrine syndromes and post-COVID conditions.

Best Publications

  • Positional cloning of the APECED gene

    Kentaro Nagamine;Pärt Peterson;Hamish S. Scott;Jun Kudoh

  • Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

    Kai Kisand;Anette S. Bøe Wolff;Katarina Trebušak Podkrajšek;Liina Tserel

  • Anti-Interferon Autoantibodies in Autoimmune Polyendocrinopathy Syndrome Type 1

    Anthony Meager;Kumuthini Visvalingam;Pärt Peterson;Kaidi Möll

  • Long latency precedes overt seroconversion in sexually transmitted human-immunodeficiency-virus infection.

    Annamari Ranki;Annamari Ranki;Minerva Krohn;Minerva Krohn;Jean-Pierre Allain;Genoveffa Franchini

  • In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6).

    P Lusso;P D Markham;E Tschachler;F di Marzo Veronese

  • Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family

    Ulla Aapola;Kazunori Shibuya;Hamish S. Scott;Juha Ollila

  • Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia

    Annamari Ranki;Marcus Nyberg;Vladimir Ovod;Matti Haltia

  • A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients

    M. C. Rosatelli;A. Meloni;M. Devoto;A. Cao

  • AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

    Steffen Meyer;Martin Woodward;Christina Hertel;Philip Vlaicu

  • The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein.

    Jukka Pitkänen;Vassilis Doucas;Thomas Sternsdorf;Toshihiro Nakajima

  • Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17α-hydroxylase

    K. Krohn;R. Uibo;E. Aavik;P. Peterson

  • Autoantibodies to cytochrome P450 enzymes P450scc, P450c17, and P450c21 in autoimmune polyglandular disease types I and II and in isolated Addison's disease

    R. Uibo;E. Aavik;P. Peterson;J. Perheentupa

  • RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse.

    Maarit Heino;Pärt Peterson;Pärt Peterson;Niko Sillanpää;Sandrine Guérin

  • Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells.

    J R Rusche;D L Lynn;M Robert-Guroff;A J Langlois

  • Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins.

    Hamish S. Scott;Maarit Heino;Pärt Peterson;Lauréane Mittaz

  • Challenge of chimpanzees (Pan troglodytes) immunized with human immunodeficiency virus envelope glycoprotein gp120.

    L O Arthur;J W Bess;D J Waters;S W Pyle

  • APECED mutations in the autoimmune regulator (AIRE) gene.

    Maarit Heino;Pärt Peterson;Jun Kudoh;Nobuyoshi Shimizu

  • Subcellular Localization of the Autoimmune Regulator Protein CHARACTERIZATION OF NUCLEAR TARGETING AND TRANSCRIPTIONAL ACTIVATION DOMAIN

    Jukka Pitkänen;Perttu Vähämurto;Kai Krohn;Pärt Peterson

  • The Calcium-Sensing Receptor Is a Target of Autoantibodies in Patients with Autoimmune Polyendocrine Syndrome Type 1

    Nikos G. Gavalas;E. Helen Kemp;Kai J. E. Krohn;Edward M. Brown

  • Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).

    P Ströbel;A Murumägi;R Klein;M Luster

  • Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines.

    A. Ranki;A. Lagerstedt;V. Ovod;E. Aavik

Frequent Co-Authors

Annamari Ranki
Annamari Ranki University of Helsinki
Pärt Peterson
Pärt Peterson University of Tartu
Raivo Uibo
Raivo Uibo University of Tartu
Hamish S. Scott
Hamish S. Scott University of Adelaide
Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva
Jun Kudoh
Jun Kudoh Keio University
Nobuyoshi Shimizu
Nobuyoshi Shimizu Keio University
Robert C. Gallo
Robert C. Gallo University of South Florida
Anthony P. Weetman
Anthony P. Weetman University of Sheffield
Kai Kisand
Kai Kisand University of Tartu

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