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Larry H. Matherly

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
11896
World Ranking
9866
National Ranking
4322

Larry H. Matherly publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Larry H. Matherly sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 279 publications — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Larry H. Matherly D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Larry H. Matherly sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 64 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Larry H. Matherly is affiliated with Wayne State University in the United States. Their research work primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with a substantial contribution to medicine. Their expertise covers a broad spectrum of subfields including molecular biology, cancer research, rheumatology, oncology, and infectious diseases.

The main research topics explored by Larry H. Matherly include:

  • Biochemical and Molecular Research
  • Folate and B Vitamins Research
  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • HIV/AIDS drug development and treatment
  • Cancer-related Molecular Pathways
  • Epigenetics and DNA Methylation

Their recent papers illustrate a focus on cancer metabolism, therapeutic targeting, and molecular pathways associated with cancer cells. Notable publications include:

  • Lipid metabolism reprogramming in renal cell carcinoma, 2021, Cancer and Metastasis Reviews
  • Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in Cancer, 2020, Molecular Cancer Therapeutics
  • Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds, 2020, British Journal of Cancer
  • FOXQ1 recruits the MLL complex to activate transcription of EMT and promote breast cancer metastasis, 2022, Nature Communications
  • Folate transporter dynamics and therapy with classic and tumor-targeted antifolates, 2021, Scientific Reports

Larry H. Matherly has collaborated frequently with several researchers, including:

  • Zhanjun Hou
  • Aleem Gangjee
  • Carrie O'Connor
  • Xun Bao
  • Md. Junayed Nayeen

The scientist's research has been disseminated in multiple publication venues with a recurring presence in:

  • Cancer Research
  • Molecular Cancer Therapeutics
  • Scientific Reports
  • Bioorganic & Medicinal Chemistry
  • Cancer Research Communications

Best Publications

  • Membrane transport of folates.

    Larry H. Matherly;I. David Goldman

  • Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.

    Rongbao Zhao;Larry H. Matherly;I. David Goldman

  • Human reduced folate carrier: translation of basic biology to cancer etiology and therapy.

    Larry H. Matherly;Zhanjun Hou;Yijun Deng

  • The cellular pharmacology of methotrexate

    I.David Goldman;Larry H. Matherly

  • Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin.

    Jeffrey W. Taub;Xi Huang;Larry H. Matherly;Mark L. Stout

  • Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells.

    So C. Wong;Susan A. Proefke;Alok Bhushan;Larry H. Matherly

  • Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines.

    Sezen Gurdag;Jayant Khandare;Sarah Stapels;Larry H. Matherly

  • New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.

    Eric C. Hales;Jeffrey W. Taub;Larry H. Matherly

  • Fecal collection, ambient preservation, and DNA extraction for PCR amplification of bacterial and human markers from human feces.

    Jordan M. Nechvatal;Jeffrey L. Ram;Marc D. Basson;Marc D. Basson;Phanramphoei Namprachan

  • Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia.

    Jeffrey W. Taub;Larry H. Matherly;Mark L. Stout;Steven A. Buck

  • The human proton-coupled folate transporter: Biology and therapeutic applications to cancer

    Sita Kugel Desmoulin;Zhanjun Hou;Aleem Gangjee;Larry H. Matherly

  • The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter.

    Johnathan R Whetstine;Robin M Flatley;Larry H Matherly

  • The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T- cell acute lymphoblastic leukemia: A report from the Children's Oncology Group

    A Larson Gedman;Q Chen;S Kugel Desmoulin;Y Ge

  • Expression of MRP4 Confers Resistance to Ganciclovir and Compromises Bystander Cell Killing

    Masashi Adachi;Janardhan Sampath;Lu Bin Lan;Daxi Sun

  • Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.

    Andong Qiu;Sang Hee Min;Michaela Jansen;Usha Malhotra

  • Role of MRP4 and MRP5 in biology and chemotherapy.

    Janardhan Sampath;Masashi Adachi;Sigrid Hatse;Lieve Naesens

  • Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency.

    Hamid M. Said;Nabendu Chatterjee;Riaz Ul Haq;Veedamali S. Subramanian

  • Biology of the Major Facilitative Folate Transporters SLC19A1 and SLC46A1

    Zhanjun Hou;Larry H. Matherly

  • High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia.

    Jeffrey W. Taub;Mark A. Konrad;Yubin Ge;John M. Naber

  • The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation.

    Maoxiang Li;Jun Ying Zhou;Yubin Ge;Larry H. Matherly

Frequent Co-Authors

Jeffrey W. Taub
Jeffrey W. Taub Wayne State University
Godefridus J. Peters
Godefridus J. Peters Gdańsk Medical University
John D. Schuetz
John D. Schuetz St. Jude Children's Research Hospital
Gerrit Jansen
Gerrit Jansen Amsterdam UMC
Yehuda G. Assaraf
Yehuda G. Assaraf Technion – Israel Institute of Technology
Roy L. Kisliuk
Roy L. Kisliuk Tufts University
Marc D. Basson
Marc D. Basson University of North Dakota
Christopher P. Leamon
Christopher P. Leamon Fusion Pharmaceuticals
Lawrence H. Lash
Lawrence H. Lash Wayne State University
I. David Goldman
I. David Goldman Albert Einstein College of Medicine

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Best Scientists Citing Larry H. Matherly

I. David Goldman

I. David Goldman

Albert Einstein College of Medicine

Publications: 76

Jeffrey W. Taub

Jeffrey W. Taub

Wayne State University

Publications: 73

Gerrit Jansen

Gerrit Jansen

Amsterdam UMC

Publications: 57

Yehuda G. Assaraf

Yehuda G. Assaraf

Technion – Israel Institute of Technology

Publications: 40

Hamid M. Said

Hamid M. Said

University of California, Irvine

Publications: 34

Godefridus J. Peters

Godefridus J. Peters

Gdańsk Medical University

Publications: 29

Richard H. Finnell

Richard H. Finnell

Baylor College of Medicine

Publications: 24

John D. Schuetz

John D. Schuetz

St. Jude Children's Research Hospital

Publications: 23

Philip S. Low

Philip S. Low

Purdue University West Lafayette

Publications: 22

John D. Crispino

John D. Crispino

Northwestern University

Publications: 22

Ching-Hon Pui

Ching-Hon Pui

St. Jude Children's Research Hospital

Publications: 21

William E. Evans

William E. Evans

St. Jude Children's Research Hospital

Publications: 19

Rob Pieters

Rob Pieters

Princess Máxima Center

Publications: 18

Mary V. Relling

Mary V. Relling

St. Jude Children's Research Hospital

Publications: 18

Lawrence H. Lash

Lawrence H. Lash

Wayne State University

Publications: 18

Paresh Vyas

Paresh Vyas

University of Oxford

Publications: 18

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