D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 8,114 136 World Ranking 7007 National Ranking 3210

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Lawrence H. Lash focuses on Glutathione, Biochemistry, Cysteine, Kidney and Molecular biology. His research in Glutathione intersects with topics in Sodium, Intracellular and Membrane permeability. Within one scientific family, Lawrence H. Lash focuses on topics pertaining to Toxicity under Biochemistry, and may sometimes address concerns connected to Cancer research.

In his study, which falls under the umbrella issue of Cysteine, Nephrotoxicity, Cysteine metabolism, Cytotoxicity, Lactate dehydrogenase and Cysteine dioxygenase is strongly linked to Aminooxyacetic acid. Lawrence H. Lash has begun a study into Kidney, looking into Internal medicine and Endocrinology. His Molecular biology research includes elements of Apoptosis, Programmed cell death, In vitro and Cell culture.

His most cited work include:

  • Compartmentation of glutathione: implications for the study of toxicity and disease. (277 citations)
  • Metabolism of trichloroethylene. (221 citations)
  • Mitochondrial glutathione transport: physiological, pathological and toxicological implications. (200 citations)

What are the main themes of his work throughout his whole career to date?

Lawrence H. Lash mostly deals with Glutathione, Biochemistry, Kidney, Internal medicine and Endocrinology. The various areas that Lawrence H. Lash examines in his Glutathione study include Oxidative stress, Molecular biology, Toxicity, Mitochondrion and Metabolism. Lawrence H. Lash works mostly in the field of Metabolism, limiting it down to topics relating to Microsome and, in certain cases, Cytochrome P450.

His Cysteine, Cytotoxicity, Enzyme, Glutathione disulfide and Intracellular investigations are all subjects of Biochemistry research. When carried out as part of a general Kidney research project, his work on Nephrotoxicity is frequently linked to work in DCVG, therefore connecting diverse disciplines of study. Many of his research projects under Endocrinology are closely connected to Glutamine synthetase with Glutamine synthetase, tying the diverse disciplines of science together.

He most often published in these fields:

  • Glutathione (55.08%)
  • Biochemistry (47.59%)
  • Kidney (28.88%)

What were the highlights of his more recent work (between 2012-2021)?

  • Oxidative stress (16.58%)
  • Glutathione (55.08%)
  • Trichloroethylene (3.21%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Oxidative stress, Glutathione, Trichloroethylene, Mitochondrion and Internal medicine. His Oxidative stress research integrates issues from Placenta, Kidney, Pharmacology and Drug metabolism. His study on Glutathione is covered under Biochemistry.

The study incorporates disciplines such as Andrology, Toxicity and Carcinogen in addition to Trichloroethylene. His Mitochondrion research focuses on Apoptosis and how it connects with Cytotoxicity, Chemically Induced Cytotoxicity, Cell growth, Cell culture and Muscle hypertrophy. His Internal medicine research focuses on subjects like Endocrinology, which are linked to Aminooxyacetic acid, Reactive oxygen species, Mitochondrial DNA and Cancer research.

Between 2012 and 2021, his most popular works were:

  • Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA). (81 citations)
  • Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard (62 citations)
  • Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity (56 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of investigation include Biochemistry, Glutathione, Hazard, Environmental health and Antibiotics. He frequently studies issues relating to Diabetic nephropathy and Biochemistry. In his articles, he combines various disciplines, including Glutathione and DCVG.

His Hazard study combines topics from a wide range of disciplines, such as Environmental epidemiology and Food safety. Immunology, Pharmacology and Structure–activity relationship is closely connected to Drug resistance in his research, which is encompassed under the umbrella topic of Antibiotics. In his study, Cytochrome P450, Metabolic pathway and Biotransformation is strongly linked to Carcinogen, which falls under the umbrella field of Metabolism.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Compartmentation of glutathione: implications for the study of toxicity and disease.

Charles V. Smith;Dean P. Jones;Thomas M. Guenthner;Lawrence H. Lash.
Toxicology and Applied Pharmacology (1996)

392 Citations

Metabolism of trichloroethylene.

Lawrence H. Lash;Jeffrey W. Fisher;John C. Lipscomb;Jean C. Parker.
Environmental Health Perspectives (2000)

328 Citations

Mitochondrial glutathione transport: physiological, pathological and toxicological implications.

Lawrence H. Lash.
Chemico-Biological Interactions (2006)

278 Citations

Exogenous glutathione protects intestinal epithelial cells from oxidative injury.

Lawrence H. Lash;Tory M. Hagen;Dean P. Jones.
Proceedings of the National Academy of Sciences of the United States of America (1986)

261 Citations

Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites.

Anders Mw;Lash L;Dekant W;Elfarra Aa.
Critical Reviews in Toxicology (1988)

251 Citations

Renal glutathione transport. Characteristics of the sodium-dependent system in the basal-lateral membrane.

L H Lash;D P Jones.
Journal of Biological Chemistry (1984)

250 Citations

Distribution of oxidized and reduced forms of glutathione and cysteine in rat plasma

Lawrence H. Lash;Dean P. Jones.
Archives of Biochemistry and Biophysics (1985)

247 Citations

Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.

L H Lash;M W Anders.
Journal of Biological Chemistry (1986)

198 Citations

Evidence for Mitochondrial Uptake of Glutathione by Dicarboxylate and 2-Oxoglutarate Carriers

Zhifeng Chen;Lawrence H. Lash.
Journal of Pharmacology and Experimental Therapeutics (1998)

191 Citations

A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions

Timothy P. Reilly;Lawrence H. Lash;Mark A. Doll;David W. Hein.
Journal of Investigative Dermatology (2000)

175 Citations

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