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Chemistry

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63
Citations
14172
World Ranking
8426
National Ranking
2425

Biology and Biochemistry

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64
Citations
15057
World Ranking
9642
National Ranking
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Overview

Arthur J. L. Cooper is a researcher affiliated with New York Medical College in the United States. Their work spans several areas within biochemistry and molecular biology, with a focus on metabolism and cancer research. Cooper has contributed to a variety of scientific publications exploring metabolic pathways and their implications for normal and cancerous cells.

Recent papers authored by Cooper include:

  • The metabolic importance of the glutaminase II pathway in normal and cancerous cells, 2020, Analytical Biochemistry
  • Metabolic Heterogeneity, Plasticity, and Adaptation to "Glutamine Addiction" in Cancer Cells: The Role of Glutaminase and the GTωA [Glutamine Transaminase-ω-Amidase (Glutaminase II)] Pathway, 2023, Biology
  • The metabolic importance of the overlooked asparaginase II pathway, 2020, Analytical Biochemistry

Cooper's research often intersects with the study of biochemical pathways relevant to cancer cell metabolism, such as glutamine metabolism and enzyme activity involved in amino acid processing.

Frequent co-authors collaborating with Cooper include:

  • Travis T. Denton
  • John T. Pinto
  • Thambi Dorai
  • Boris F. Krasnikov
  • Giang Hoang

The scholar's work has been published predominantly in the following venues:

  • Analytical Biochemistry
  • Advanced Biology
  • Antioxidants
  • Biology
  • International Journal of Molecular Sciences

Cooper's main fields of study are Biochemistry, Genetics and Molecular Biology, and Medicine. Within these disciplines, their subfields include Molecular Biology, Cancer Research, Biochemistry, Biotechnology, and Physiology.

The primary research topics covered by Cooper are:

  • Cancer, Hypoxia, and Metabolism
  • Cancer Research and Treatments
  • Amino Acid Enzymes and Metabolism
  • Biochemical and Molecular Research
  • Diet and Metabolism Studies
  • Metabolism and Genetic Disorders
  • Sulfur Compounds in Biology

Overall, the body of work indicates a specialized focus on metabolic pathways related to cancer and enzymatic processes, contributing to understanding biochemical mechanisms that underlie disease states and normal physiology.

Best Publications

  • Biochemistry and physiology of brain ammonia.

    Unknown

  • Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

    Stephen P. Raps;James C.K. Lai;Leif Hertz;Arthur J.L. Cooper

  • Vitamin E, Ascorbate, Glutathione, Glutathicne Disulfide, and Enzymes of Glutathione Metabolism in Cultures of Chick Astrocytes and Neurons: Evidence that Astrocytes Play an Important Role in Antioxidative Processes in the Brain

    T. K. Makar;M. Nedergaard;A. Preuss;A. S. Gelbard

  • The metabolic fate of 13N-labeled ammonia in rat brain.

    A J Cooper;J M McDonald;A S Gelbard;R F Gledhill

  • Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors.

    James C. K. Lai;Arthur J. L. Cooper

  • BIOCHEMISTRY OF SULFUR-CONTAINING AMINO ACIDS

    Unknown

  • Therapeutic effects of cystamine in a murine model of Huntington's disease.

    Alpaslan Dedeoglu;Alpaslan Dedeoglu;James K. Kubilus;James K. Kubilus;Thomas M. Jeitner;Samantha A. Matson

  • Plant phenylacetaldehyde synthase is a bifunctional homotetrameric enzyme that catalyzes phenylalanine decarboxylation and oxidation.

    Yasuhisa Kaminaga;Jennifer Schnepp;Greg Peel;Christine M. Kish

  • Synthesis and properties of the .alpha.-keto acids

    Arthur J. L. Cooper;James Z. Ginos;Alton Meister

  • Glutathione and ascorbate during ischemia and postischemic reperfusion in rat brain.

    Arthur J. L. Cooper;William A. Pulsinelli;Thomas E. Duffy

  • Zn2+ Inhibits α-Ketoglutarate-stimulated Mitochondrial Respiration and the Isolated α-Ketoglutarate Dehydrogenase Complex *

    Abraham M. Brown;Bruce S. Kristal;Michelle S. Effron;Alexander I. Shestopalov

  • Astrocyte glutamine synthetase: Importance in hyperammonemic syndromes and potential target for therapy

    Saul W. Brusilow;Raymond C. Koehler;Richard J. Traystman;Arthur J. L. Cooper

  • Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain

    Arthur J. L. Cooper;Thomas M. Jeitner

  • Brain glutamine synthetase increases following cerebral ischemia in the rat.

    Carol K. Petito;Marilda C. Chung;Lena M. Verkhovsky;Arthur J.L. Cooper

  • Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology

    John I. Toohey;Arthur J. L. Cooper

  • Reversible and Irreversible Protein Glutathionylation: Biological and Clinical Aspects

    Arthur J L. Cooper;John T. Pinto;Patrick S. Callery

  • Short-term metabolic fate of [13N]ammonia in rat liver in vivo.

    A. J. L. Cooper;E. Nieves;A. E. Coleman;S. Filc-Dericco

  • Isolation and Properties of a New Glutamine Transaminase from Rat Kidney

    Arthur J.L. Cooper;Alton Meister

  • Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

    Stephen J. McConoughey;Stephen J. McConoughey;Manuela Basso;Zoya V. Niatsetskaya;Sama F. Sleiman

  • [13N]Cisplatin PET to Assess Pharmacokinetics of Intra-Arterial versus Intravenous Chemotherapy for Malignant Brain Tumors

    James Z. Ginos;Arthur J. L. Cooper;Vijay Dhawan;James C. K. Lai

Frequent Co-Authors

John P. Blass
John P. Blass Cornell University
Yasuhisa Asano
Yasuhisa Asano Toyama Prefectural University
M. Flint Beal
M. Flint Beal Cornell University
Andrew D. Hanson
Andrew D. Hanson University of Florida
Gary E. Gibson
Gary E. Gibson Cornell University
Bruce S. Kristal
Bruce S. Kristal Brigham and Women's Hospital
James R. Burke
James R. Burke Duke University
Paula M. Alves
Paula M. Alves Universidade Nova de Lisboa
David Rhodes
David Rhodes Purdue University West Lafayette
Warren J. Strittmatter
Warren J. Strittmatter Duke University

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