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D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
17458
World Ranking
5674
National Ranking
2688

Overview

Ping-Yee Law is affiliated with the University of Minnesota in the United States with a research focus primarily in biochemistry, genetics, and molecular biology. Their scientific contributions emphasize molecular biology and cellular and molecular neuroscience, with additional work in developmental neuroscience, anesthesiology and pain medicine, and physiology.

Their research has contributed to multiple key topics, including:

  • Neurogenesis and neuroplasticity mechanisms
  • Receptor mechanisms and signaling
  • Pharmacological receptor mechanisms and effects
  • Neuropeptides and animal physiology
  • Pain management and opioid use
  • Pain mechanisms and treatments
  • Opioid use disorder treatment

Ping-Yee Law has published extensively in journals with frequent contributions to:

  • Cytotherapy
  • Cellular and Molecular Neurobiology
  • Stem Cells
  • Cell Reports
  • The FASEB Journal

Their recent scientific papers include:

  • Oxycodone in the Opioid Epidemic: High 'Liking', 'Wanting', and Abuse Liability, 2020, Cellular and Molecular Neurobiology
  • Kappa opioid receptor controls neural stem cell differentiation via a miR-7a/Pax6 dependent pathway, 2021, Stem Cells
  • Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway, 2020, Cell Reports
  • Naloxone regulates the differentiation of neural stem cells via a receptor-independent pathway, 2020, The FASEB Journal
  • Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone, 2022, Bioorganic Chemistry

Frequent collaborators of Ping-Yee Law include:

  • Jaap Jan Boelens
  • Rachele Ciccocioppo
  • Nancy Collins
  • Charles S. Cox
  • Natividad Cuende

Best Publications

  • Molecular Mechanisms and Regulation of Opioid Receptor Signaling

    Ping Yee Law;Yung H. Wong;Horace H Loh

  • Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord

    Ulf Arvidsson;Maureen Riedl;Sumita Chakrabarti;Jang Hern Lee

  • Morphine Stimulates Angiogenesis by Activating Proangiogenic and Survival-promoting Signaling and Promotes Breast Tumor Growth

    Kalpna Gupta;Smita Kshirsagar;Liming Chang;Robert Schwartz

  • Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness

    Jie Zhang;Stephen S. G. Ferguson;Stephen S. G. Ferguson;Larry S. Barak;Sobha R. Bodduluri

  • VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling.

    Kalpna Gupta;Smita Kshirsagar;Wei Li;Lizhen Gui

  • Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series

    David J. Daniels;Natalie R. Lenard;Chris L. Etienne;Ping Yee Law

  • Opiate receptor down-regulation and desensitization in neuroblastoma X glioma NG108-15 hybrid cells are two separate cellular adaptation processes.

    P Y Law;D S Hom;H H Loh

  • Regulation of Opioid Receptor Activities

    Ping Yee Law;Horace H Loh

  • The role of membrane lipids in receptor mechanisms.

    H H Loh;P Y Law

  • Immunofluorescent identification of a delta (delta)-opioid receptor on primary afferent nerve terminals.

    Robert J. Dado;P. Y. Law;Horace H Loh;Robert Elde

  • β-Arrestin-Dependent μ-Opioid Receptor-Activated Extracellular Signal-Regulated Kinases (ERKs) Translocate to Nucleus in Contrast to G Protein-Dependent ERK Activation

    Hui Zheng;Horace H. Loh;Ping-Yee Law

  • Demonstration and Characterization of Opiate Inhibition of the Striatal Adenylate Cyclase

    P. Y. Law;J. Wu;J. E. Koehler;H. H. Loh

  • Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes.

    Ping-Yee Law;D. S. Hom;Horace H Loh

  • The kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids

    U Arvidsson;M Riedl;S Chakrabarti;L Vulchanova

  • Loss of opiate receptor activity in neuroblastoma X glioma NG108-15 hybrid cells after chronic opiate treatment. A multiple-step process.

    P Y Law;D S Hom;H H Loh

  • Decrease in delta and mu opioid receptor binding capacity in rat brain after chronic etorphine treatment.

    P. L. Tao;Ping-Yee Law;Horace H Loh

  • Phosphorylation of Ser363, Thr370, and Ser375 Residues within the Carboxyl Tail Differentially Regulates μ-Opioid Receptor Internalization *

    Rachid El Kouhen;Amy L. Burd;Laurie J. Erickson-Herbrandson;Chia Yu Chang

  • Poly(C)-binding proteins as transcriptional regulators of gene expression

    Hack Sun Choi;Cheol Kyu T Hwang;Kyu Young Song;Ping-Yee Law

  • Heterodimerization of μ- and δ-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions

    Ping Yee Law;Laurie J. Erickson-Herbrandson;Qin Q. Zha;Jon Solberg

  • Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy.

    Yulong L. Chen;Ping-Yee Law;Horace H Loh

Frequent Co-Authors

Horace H. Loh
Horace H. Loh University of Minnesota
Horace H. Loh
Horace H. Loh University of Minnesota
Li-Na Wei
Li-Na Wei University of Minnesota
Robert Elde
Robert Elde University of Minnesota
Choh Hao Li
Choh Hao Li University of California, San Francisco
Philip S. Portoghese
Philip S. Portoghese University of Minnesota
Hao Sun
Hao Sun Chinese University of Hong Kong
Christopher J. Evans
Christopher J. Evans University of California, Los Angeles
Ulf Arvidsson
Ulf Arvidsson Karolinska Institute
Albert Herz
Albert Herz Max Planck Society

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