Lee-Yuan Liu-Chen

Research.com Recognitions

• 1989 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites

  Bojan Lalovic;Bojan Lalovic;Bojan Lalovic;Evan Kharasch;Evan Kharasch;Evan Kharasch;Christine Hoffer;Christine Hoffer;Christine Hoffer;Linda Risler;Linda Risler;Linda Risler

  505
  Citations

• Comparison of Pharmacological Activities of Buprenorphine and Norbuprenorphine: Norbuprenorphine Is a Potent Opioid Agonist

  Peng Huang;George B. Kehner;Alan Cowan;Lee Yuan Liu-Chen

  404
  Citations

• Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.

  Yulin Wang;Kang Tang;Saadet Inan;Daniel J. Siebert

  272
  Citations

• Molecular cloning and expression of a rat kappa opioid receptor.

  Shuixing Li;Jinmin Zhu;Chongguang Chen;Yung-Wu Chen

  262
  Citations

• U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation.

  Jian-Guo Li;Lai-Yi Luo;Jason G. Krupnick;Jeffrey L. Benovic

  211
  Citations

• The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.

  Edward J. Weinman;Randy A. Hall;Peter A. Friedman;Lee-Yuan Liu-Chen

  203
  Citations

• Heterodimerization and cross-desensitization between the μ-opioid receptor and the chemokine CCR5 receptor

  Chongguang Chen;Jin Li;George Bot;Imre Szabo

  199
  Citations

• Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

  Stephen D. Mague;Carolina Isiegas;Peng Huang;Lee-Yuan Liu-Chen

  197
  Citations

• Immunohistochemical evidence for a substance P-containing trigeminovascular pathway to pial arteries in cats

  Lee-Yuan Liu-Chen;Lee-Yuan Liu-Chen;Marc R. Mayberg;Michael A. Moskowitz;Michael A. Moskowitz

  195
  Citations

• Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.

  Jinmin Zhu;Lai-Yi Luo;Jian-Guo Li;Chongguang Chen

  183
  Citations

• Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor.

  Ji-Chun Xue;Chongguang Chen;Jinmin Zhu;S. Kunapuli

  173
  Citations

• Ezrin-Radixin-Moesin-binding Phosphoprotein-50/Na+/H+ Exchanger Regulatory Factor (EBP50/NHERF) Blocks U50,488H-induced Down-regulation of the Human κ Opioid Receptor by Enhancing Its Recycling Rate *

  Jian-Guo Li;Chongguang Chen;Lee-Yuan Liu-Chen

  164
  Citations

• In vitro release of immunoreactive substance P from putative afferent nerve endings in bovine pia arachnoid.

  M.A. Moskowitz;M.A. Moskowitz;M. Brody;L.-Y. Liu-Chen;L.-Y. Liu-Chen

  151
  Citations

• Mephedrone ('bath salt') elicits conditioned place preference and dopamine-sensitive motor activation.

  Renata Lisek;Wei Xu;Ekaterina Yuvasheva;Yi-Ting Chiu

  151
  Citations

• Mutational Analysis of Gβγ and Phospholipid Interaction with G Protein-coupled Receptor Kinase 2

  Christopher V. Carman;Larry S. Barak;Chongguang Chen;Lee-Yuan Liu-Chen

  147
  Citations

• Dual ultrastructural immunocytochemical labeling of mu and delta opioid receptors in the superficial layers of the rat cervical spinal cord.

  Peter Y Cheng;Lee-Yuan Liu-Chen;Virginia M Pickel

  139
  Citations

• 6′-Guanidinonaltrindole (6′-GNTI) Is a G Protein-biased κ-Opioid Receptor Agonist That Inhibits Arrestin Recruitment

  Marie-Laure Rives;Mary Rossillo;Lee-Yuan Liu-Chen;Jonathan A. Javitch

  139
  Citations

• Cloning of a human κ opioid receptor from the brain

  Jinmin Zhu;Chongguang Chen;Ji-Chun Xue;Satya Kunapuli

  138
  Citations

• A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability.

  Peng Huang;Chongguang Chen;Stephen D. Mague;Julie A. Blendy

  137
  Citations

• Co-localization of retrogradely transported wheat germ agglutinin and the putative neurotransmitter substance P within trigeminal ganglion cells projecting to cat middle cerebral artery.

  Lee‐Yuan Liu‐Chen;Steven A. Gillespie;Thorkild V. Norregaard;Michael A. Moskowitz

  132
  Citations