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Florian Gnad

Florian Gnad

D-Index & Metrics

Molecular Biology

D-Index
51
Citations
24850
World Ranking
2458
National Ranking
164

Overview

Florian Gnad is affiliated with Roche in Germany and conducts research primarily in the fields of biochemistry, genetics, molecular biology, and medicine. Their work spans several interconnected subfields, including molecular biology, pulmonary and respiratory medicine, and pathology and forensic medicine.

The research focuses on significant biological and medical topics such as genomics, phytochemicals, and oxidative stress; ferroptosis and cancer prognosis; circular RNAs in diseases; cancer mechanisms and therapy; PI3K/AKT/mTOR signaling in cancer; protein degradation and inhibitors; and bioinformatics and genomic networks.

Notable recent publications by Florian Gnad include:

  • NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes, 2020, Clinical Cancer Research
  • Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors, 2022, Nature Communications
  • Applying graph database technology for analyzing perturbed co-expression networks in cancer, 2020, Database

The scientist has frequently published in the following venues:

  • Clinical Cancer Research
  • Nature Communications
  • Database

Florian Gnad has collaborated with multiple researchers over their career, with frequent co-authors including:

  • Anneleen Daemen
  • Anju Singh
  • Dorothee Nickles
  • Sang-Min Jeon
  • Oded Foreman

Best Publications

  • Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

    Chuna Ram Choudhary;Chanchal Kumar;Florian Gnad;Michael L Nielsen

  • Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

    Jesper V. Olsen;Blagoy Blagoev;Florian Gnad;Boris Macek;Boris Macek

  • Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

    Jesper V. Olsen;Michiel Vermeulen;Anna Santamaria;Chanchal Kumar

  • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

    Charles M Rudin;Steffen Durinck;Eric W Stawiski;John T Poirier

  • Recurrent R-spondin fusions in colon cancer

    Somasekar Seshagiri;Eric W. Stawiski;Steffen Durinck;Zora Modrusan

  • Precision Mapping of an In Vivo N-Glycoproteome Reveals Rigid Topological and Sequence Constraints

    Dorota F. Zielinska;Florian Gnad;Florian Gnad;Jacek R. Wiśniewski;Matthias Mann

  • Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

    Raphael Bueno;Eric W Stawiski;Leonard D Goldstein;Steffen Durinck

  • Kinase-Selective Enrichment Enables Quantitative Phosphoproteomics of the Kinome across the Cell Cycle

    Henrik Daub;Jesper V. Olsen;Michaela Bairlein;Florian Gnad

  • A comprehensive transcriptional portrait of human cancer cell lines

    Christiaan Klijn;Steffen Durinck;Eric W Stawiski;Peter M Haverty

  • PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites.

    Florian Gnad;Shubin Ren;Juergen Cox;Jesper V Olsen

  • Phosphoproteome Analysis of E. coli Reveals Evolutionary Conservation of Bacterial Ser/Thr/Tyr Phosphorylation

    Boris Macek;Florian Gnad;Boumediene Soufi;Chanchal Kumar

  • The Serine/Threonine/Tyrosine Phosphoproteome of the Model Bacterium Bacillus subtilis

    Boris Macek;Ivan Mijakovic;Jesper V. Olsen;Florian Gnad

  • PHOSIDA 2011: the posttranslational modification database

    Florian Gnad;Jeremy Gunawardena;Matthias Mann

  • Large-scale Proteomics Analysis of the Human Kinome

    Felix S. Oppermann;Florian Gnad;Jesper V. Olsen;Renate Hornberger

  • Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif

    Ivan Matic;Joost Schimmel;Ivor .A. Hendriks;Maria A. van Santen

  • USP7 small-molecule inhibitors interfere with ubiquitin binding

    Lorna Kategaya;Paola Di Lello;Lionel Rougé;Richard Pastor

  • Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover.

    Sidney B. Cambridge;Florian Gnad;Chuong Nguyen;Justo Lorenzo Bermejo

  • Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology.

    Jacek R. Wiśniewski;Nagarjuna Nagaraj;Alexandre Zougman;Florian Gnad

  • Mapping N-Glycosylation Sites across Seven Evolutionarily Distant Species Reveals a Divergent Substrate Proteome Despite a Common Core Machinery

    Dorota F. Zielinska;Florian Gnad;Katharina Schropp;Jacek R. Wiśniewski

  • Abstract LB-331: Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

    Somasekar Seshagiri;Eric Stawiski;Leonard Goldstein;Steffen Durinck

Frequent Co-Authors

Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Jesper V. Olsen
Jesper V. Olsen University of Copenhagen
Boris Macek
Boris Macek University of Tübingen
Zemin Zhang
Zemin Zhang Peking University
Zora Modrusan
Zora Modrusan Genentech
Jinfeng Liu
Jinfeng Liu Genentech
Gerard Manning
Gerard Manning University College Cork

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