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Biology and Biochemistry

D-Index
75
Citations
26133
World Ranking
5234
National Ranking
403

Overview

Shabaz Mohammed is affiliated with the University of Oxford in the United Kingdom. Their research focuses primarily on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology. Their work spans several specialized subfields including spectroscopy, immunology, oncology, and cell biology.

The scientist has published extensively on topics related to RNA and protein synthesis mechanisms, RNA research and splicing, RNA modifications and cancer, advanced proteomics techniques and applications, mass spectrometry techniques and applications, click chemistry and its applications, as well as interferon and immune responses.

Among recent publications are notable papers such as "Light-driven post-translational installation of reactive protein side chains" (2020, Nature), "Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection" (2021, Molecular Cell), "Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method" (2020, Biomolecules), "Direct radical functionalization of native sugars" (2024, Nature), and "Lipids mediate supramolecular outer membrane protein assembly in bacteria" (2022, Science Advances).

Frequent collaborators include Benjamin G. Davis, Alfredo Castelló, Yana Demyanenko, Wael Kamel, and Andrew M. Giltrap. Their scientific contributions have been disseminated through a variety of venues, with the most frequent publications appearing in bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Communications, Science Advances, and Analytical Chemistry.

  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Advanced Proteomics Techniques and Applications
  • Mass Spectrometry Techniques and Applications
  • Click Chemistry and Applications
  • interferon and immune responses

  • Light-driven post-translational installation of reactive protein side chains (2020, Nature)
  • Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection (2021, Molecular Cell)
  • Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method (2020, Biomolecules)
  • Direct radical functionalization of native sugars (2024, Nature)
  • Lipids mediate supramolecular outer membrane protein assembly in bacteria (2022, Science Advances)

  • Benjamin G. Davis
  • Alfredo Castelló
  • Yana Demyanenko
  • Wael Kamel
  • Andrew M. Giltrap

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • Science Advances
  • Analytical Chemistry

The scope and diversity of Shabaz Mohammed's research work reflect a comprehensive engagement with molecular biology and biochemistry, addressing multiple aspects of RNA and protein function as well as innovative proteomic and chemical biology techniques.

Best Publications

  • The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

    Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert

  • Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics.

    Paul J Boersema;Reinout Raijmakers;Simone Lemeer;Simone Lemeer;Shabaz Mohammed

  • Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

    Wim De Lau;Nick Barker;Nick Barker;Teck Y. Low;Bon Kyoung Koo

  • Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

    Bon-Kyoung Koo;Maureen Spit;Ingrid Jordens;Teck Y. Low

  • Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex

    Vivian S.W. Li;Ser Sue Ng;Paul J. Boersema;Teck Y. Low

  • Quantitative Phosphoproteomics Applied to the Yeast Pheromone Signaling Pathway

    Albrecht Gruhler;Jesper Velgaard Olsen;Shabaz Mohammed;Peter Mortensen

  • Quantitative Phosphoproteomics of Early Elicitor Signaling in Arabidopsis

    Joris J. Benschop;Shabaz Mohammed;Martina O'Flaherty;Albert J.R. Heck

  • The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

    Javier Muñoz;Daniel E Stange;Arnout G Schepers;Marc van de Wetering

  • Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

    Raul Rojas;Thijs van Vlijmen;Gonzalo A. Mardones;Yogikala Prabhu

  • Toward a comprehensive characterization of a human cancer cell phosphoproteome

    Houjiang Zhou;Serena Di Palma;Christian Preisinger;Mao Peng

  • Phosphopeptide fragmentation and analysis by mass spectrometry

    Paul J. Boersema;Shabaz Mohammed;Albert J. R. Heck

  • Robust phosphoproteome enrichment using monodisperse microsphere–based immobilized titanium (IV) ion affinity chromatography

    Houjiang Zhou;Mingliang Ye;Jing Dong;Eleonora Corradini

  • Improved Peptide Identification by Targeted Fragmentation Using CID, HCD and ETD on an LTQ-Orbitrap Velos

    Christian K. Frese;A. F. Maarten Altelaar;Marco L. Hennrich;Dirk Nolting

  • Hydrophilic interaction liquid chromatography (HILIC) in proteomics

    Paul J. Boersema;Shabaz Mohammed;Albert J. R. Heck

  • Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach

    Sharon Gauci;Andreas O. Helbig;Monique Slijper;Jeroen Krijgsveld

  • A systematic approach to modeling, capturing, and disseminating proteomics experimental data.

    Chris F. Taylor;Norman W. Paton;Kevin L. Garwood;Paul D. Kirby

  • hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing.

    Greta Pintacuda;Guifeng Wei;Chloë Roustan;Burcu Anil Kirmizitas

  • Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry.

    Christian K. Frese;A. F. Maarten Altelaar;Henk van den Toorn;Dirk Nolting

  • An optimized protocol for metabolome analysis in yeast using direct infusion electrospray mass spectrometry.

    Juan I Castrillo;Andrew Hayes;Shabaz Mohammed;Simon J Gaskell

  • The Generating Function of CID, ETD, and CID/ETD Pairs of Tandem Mass Spectra: Applications to Database Search

    Sangtae Kim;Nikolai Mischerikow;Nuno Bandeira;Nuno Bandeira;J. Daniel Navarro

Frequent Co-Authors

Alfredo Castello
Alfredo Castello MRC-University of Glasgow Centre For Virus Research
Benjamin G. Davis
Benjamin G. Davis University of Oxford
Ole Nørregaard Jensen
Ole Nørregaard Jensen University of Southern Denmark
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Carol V. Robinson
Carol V. Robinson University of Oxford
René H. Medema
René H. Medema Princess Máxima Center
Marc van de Wetering
Marc van de Wetering Royal Netherlands Academy of Arts and Sciences
Simon J. Gaskell
Simon J. Gaskell Plymouth University
Nullin Divecha
Nullin Divecha University of Southampton

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