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Molecular Biology

D-Index
71
Citations
18888
World Ranking
1374
National Ranking
698

Overview

Arthur I. Skoultchi is affiliated with the Albert Einstein College of Medicine in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a significant number of publications in the subfields of Molecular Biology, Immunology, Hematology, Plant Science, and Cell Biology.

The main topics of their research include:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • DNA Repair Mechanisms
  • Retinal Development and Disorders
  • Cellular transport and secretion
  • Hematopoietic Stem Cell Transplantation

Skoultchi has contributed articles to a variety of scientific venues with a notable presence in bioRxiv (Cold Spring Harbor Laboratory) and Nature, as well as publications in Proceedings of the National Academy of Sciences, eLife, and UNC Libraries.

Recent publications include:

  • "Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture," 2020, Nature
  • "H1 histones control the epigenetic landscape by local chromatin compaction," 2020, Nature
  • "Single-molecule imaging of transcription dynamics in somatic stem cells," 2020, Nature
  • "H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction," 2020, Proceedings of the National Academy of Sciences
  • "The chromatin remodeler Snf2h is essential for oocyte meiotic cell cycle progression," 2020, Genes & Development

They have collaborated frequently with:

  • Hugo Pinto
  • Dmitry V. Fyodorov
  • Michael-Christopher Keogh
  • Michael A. Willcockson
  • Zbyněk Kozmík

Best Publications

  • A comparative encyclopedia of DNA elements in the mouse genome

    Feng Yue;Feng Yue;Yong Cheng;Alessandra Breschi;Jeff Vierstra

  • TBX1 Is Responsible for Cardiovascular Defects in Velo-Cardio-Facial/DiGeorge Syndrome

    Sandra Merscher;Birgit Funke;Jonathan A. Epstein;Joerg Heyer

  • Histone H1 Depletion in Mammals Alters Global Chromatin Structure but Causes Specific Changes in Gene Regulation

    Yuhong Fan;Tatiana Nikitina;Jie Zhao;Tomara J. Fleury

  • Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

    Natasha Rekhtman;Farshid Radparvar;Todd Evans;Arthur I. Skoultchi

  • Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

    Ragnhild Eskeland;Martin Leeb;Graeme R. Grimes;Clémence Kress

  • Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length

    Christopher L. Woodcock;Arthur I. Skoultchi;Yuhong Fan

  • An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

    Nicole Schreiber-Agus;Lynda Chin;Ken Chen;Richard Torres

  • Expression of c-myc changes during differentiation of mouse erythroleukaemia cells

    Herbert M. Lachman;Arthur I. Skoultchi

  • Pax3 functions at a nodal point in melanocyte stem cell differentiation

    Deborah Lang;Min Min Lu;Li Huang;Kurt A. Engleka

  • Emerging roles of linker histones in regulating chromatin structure and function

    Dmitry V. Fyodorov;Bing Rui Zhou;Arthur I. Skoultchi;Yawen Bai

  • Involvement of Histone H1.2 in Apoptosis Induced by DNA Double-Strand Breaks

    Akimitsu Konishi;Akimitsu Konishi;Shigeomi Shimizu;Junko Hirota;Toshifumi Takao

  • H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo.

    Yuhong Fan;Tatiana Nikitina;Elizabeth M. Morin-Kensicki;Jie Zhao

  • Coordinating cell proliferation and differentiation

    Liang Zhu;Arthur I Skoultchi

  • Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution

    Jeff Vierstra;Eric Rynes;Richard Sandstrom;Miaohua Zhang

  • Global chromatin compaction limits the strength of the DNA damage response.

    Matilde Murga;Isabel Jaco;Yuhong Fan;Rebeca Soria

  • Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype.

    Yuhong Fan;Allen Sirotkin;Robert G. Russell;Julianna Ayala

  • The ISWI ATPase Snf2h is required for early mouse development

    Tomas Stopka;Arthur I. Skoultchi

  • Mice develop normally without the H1(0) linker histone.

    Allen M. Sirotkin;Winfried Edelmann;Genhong Cheng;Andres Klein-Szanto

  • CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.

    Masaaki Nishiyama;Kiyotaka Oshikawa;Yu Ichi Tsukada;Tadashi Nakagawa

  • Cell cycle regulation of mouse H3 histone mRNA metabolism.

    R. B. Alterman;S. Ganguly;D. H. Schulze;William F Marzluff

Frequent Co-Authors

Raju Kucherlapati
Raju Kucherlapati Harvard University
Jiri Zavadil
Jiri Zavadil International Agency For Research On Cancer
Bernice E. Morrow
Bernice E. Morrow Albert Einstein College of Medicine
Michael Snyder
Michael Snyder Stanford University
Ulrich Steidl
Ulrich Steidl Albert Einstein College of Medicine
Birgit Funke
Birgit Funke Harvard University
Ales Cvekl
Ales Cvekl Albert Einstein College of Medicine
Mark Groudine
Mark Groudine Fred Hutchinson Cancer Research Center
John A. Stamatoyannopoulos
John A. Stamatoyannopoulos University of Washington

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