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Biology and Biochemistry

D-Index
64
Citations
12384
World Ranking
9824
National Ranking
4305

Overview

Ulrich Steidl is affiliated with the Albert Einstein College of Medicine in the United States. Their research contributions span the fields of medicine and biochemistry, genetics, and molecular biology, with a focus on several subfields including molecular biology, hematology, immunology, oncology, and genetics.

The main topics addressed in their work include:

  • Acute Myeloid Leukemia Research
  • Protein Degradation and Inhibitors
  • Epigenetics and DNA Methylation
  • Hematopoietic Stem Cell Transplantation
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Acute Lymphoblastic Leukemia research

Ulrich Steidl has published extensively in several scientific journals. The most frequent publication venues include:

  • Blood
  • Experimental Hematology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research
  • Nature Cancer

Among their recent papers are the following notable works:

  • "Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53" (2021) published in Clinical Cancer Research
  • "A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy" (2020) in Nature Cancer
  • "Delayed clearance of SARS-CoV2 in male compared to female patients: High ACE2 expression in testes suggests possible existence of gender-specific viral reservoirs" (2020) in bioRxiv (Cold Spring Harbor Laboratory)
  • "Single-molecule imaging of transcription dynamics in somatic stem cells" (2020) in Nature
  • "H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction" (2020) in Proceedings of the National Academy of Sciences

Ulrich Steidl has collaborated frequently with a set of coauthors, including:

  • Aditi Shastri
  • Kith Pradhan
  • Amit Verma
  • Kira Gritsman
  • Mendel Goldfinger

Best Publications

  • MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

    Christian Steidl;Sohrab P. Shah;Bruce W. Woolcock;Lixin Rui

  • Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

    Eric M. Pietras;Cristina Mirantes-Barbeito;Sarah Fong;Dirk Loeffler

  • Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

    Frank Rosenbauer;Frank Rosenbauer;Bronwyn M. Owens;Li Yu;Joseph R. Tumang

  • Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

    Britta Will;Li Zhou;Thomas O. Vogler;Susanna Ben-Neriah

  • Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes.

    I Gañán-Gómez;Y Wei;D T Starczynowski;S Colla

  • Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.

    Alan H. Shih;Yanwen Jiang;Cem Meydan;Kaitlyn Shank

  • Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.

    Laura Barreyro;Britta Will;Boris Bartholdy;Li Zhou

  • Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

    Luis A. Carvajal;Daniela Ben Neriah;Adrien Senecal;Lumie Benard

  • Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cells.

    Ulrich Steidl;Ralf Kronenwett;Ralf Kronenwett;Ulrich Peter Rohr;Ulrich Peter Rohr;Roland Fenk;Roland Fenk

  • U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.

    Molly A. Smith;Molly A. Smith;Gaurav S. Choudhary;Andrea Pellagatti;Kwangmin Choi

  • PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

    Alexander K. Ebralidze;Florence C. Guibal;Ulrich Steidl;Pu Zhang

  • Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells

    Ulrich Steidl;Frank Rosenbauer;Frank Rosenbauer;Roel G W Verhaak;Xuesong Gu

  • Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level.

    Jiahao Chen;Yun Ruei Kao;Daqian Sun;Tihomira I. Todorova

  • Fast and reliable titration of recombinant adeno-associated virus type-2 using quantitative real-time PCR.

    Ulrich Peter Rohr;Marc Andre Wulf;Susanne Stahn;Ulrich Steidl

  • IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

    Carolina Schinke;Orsolya Giricz;Weijuan Li;Aditi Shastri

  • A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability

    Volker Patzel;Ulrich Steidl;Ralf Kronenwett;Rainer Haas

  • New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

    Ujunwa C. Okoye-Okafor;Boris Bartholdy;Jessy Cartier;Enoch N. Gao

  • Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling.

    Susumu Kobayashi;Takeshi Shimamura;Stefano Monti;Ulrich Steidl

  • Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediators.

    Ulrich Steidl;Simone Bork;Sebastian Schaub;Oliver Selbach

  • Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation

    Michael Roth;Michael Roth;Britta Will;Guillermo Simkin;Swathi Narayanagari

Frequent Co-Authors

Amit Verma
Amit Verma Albert Einstein College of Medicine
Andrea Pellagatti
Andrea Pellagatti University of Oxford
Amittha Wickrema
Amittha Wickrema University of Chicago
John M. Greally
John M. Greally Albert Einstein College of Medicine
Daniel G. Tenen
Daniel G. Tenen National University of Singapore
Christian Steidl
Christian Steidl University of British Columbia
Ari Melnick
Ari Melnick Cornell University
Ross L. Levine
Ross L. Levine Memorial Sloan Kettering Cancer Center
Alan F. List
Alan F. List Precision BioSciences
Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic

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