Amittha Wickrema

Overview

Best Publications

• Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells.

  K Muta;S B Krantz;M C Bondurant;A Wickrema

  247
  Citations

• Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells.

  Yair Gazitt;Chris C. Reading;Ron Hoffman;Amittha Wickrema

  220
  Citations

• Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production.

  Linda L. Kelley;Mark J. Koury;Maurice C. Bondurant;Stephen T. Koury

  207
  Citations

• Protein Kinase B (c-Akt), Phosphatidylinositol 3-Kinase, and STAT5 Are Activated by Erythropoietin (EPO) in HCD57 Erythroid Cells But Are Constitutively Active in an EPO-Independent, Apoptosis-Resistant Subclone (HCD57-SREI Cells)

  Haifeng Bao;Sarah M. Jacobs-Helber;Sarah M. Jacobs-Helber;Sarah M. Jacobs-Helber;Amy E. Lawson;Amy E. Lawson;Amy E. Lawson;Kalyani Penta;Kalyani Penta;Kalyani Penta

  203
  Citations

• Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions

  Hongtao Liu;Elizabeth S. Rich;Lucy Godley;Olatoyosi Odenike

  201
  Citations

• Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells.

  Amittha Wickrema;Sanford B. Krantz;Sanford B. Krantz;John C. Winkelmann;John C. Winkelmann;Maurice C. Bondurant;Maurice C. Bondurant

  201
  Citations

• Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS

  Li Zhou;Aaron N. Nguyen;Davendra Sohal;Jing Ying Ma

  193
  Citations

• Activation of the p38 Mitogen-activated Protein Kinase Mediates the Suppressive Effects of Type I Interferons and Transforming Growth Factor-β on Normal Hematopoiesis

  Amit K. Verma;Dilip K. Deb;Antonella Sassano;Shahab Uddin

  191
  Citations

• IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

  Carolina Schinke;Orsolya Giricz;Weijuan Li;Aditi Shastri

  188
  Citations

• Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells.

  Shahab Uddin;Jeong Ah-Kang;Jodie Ulaszek;Dolores Mahmud

  182
  Citations

• The hSK4 (KCNN4) isoform is the Ca2+-activated K+ channel (Gardos channel) in human red blood cells

  Joseph F. Hoffman;William Joiner;Keith Nehrke;Olga Potapova

  174
  Citations

• Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells [see comments]

  A Wickrema;SB Krantz;JC Winkelmann;MC Bondurant

  165
  Citations

• Fludarabine, Melphalan, and Alemtuzumab Conditioning in Adults With Standard-Risk Advanced Acute Myeloid Leukemia and Myelodysplastic Syndrome

  Koen van Besien;A. Artz;S. Smith;D. Cao

  154
  Citations

• Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells.

  Dolores L Mahmud;Maaza G-Amlak;Dilip K Deb;Leonidas C Platanias

  153
  Citations

• Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase

  Li Zhou;Christine McMahon;Tushar Bhagat;Cristina Alencar

  148
  Citations

• AP1 Regulation of Proliferation and Initiation of Apoptosis in Erythropoietin-Dependent Erythroid Cells

  Sarah M. Jacobs-Helber;Amittha Wickrema;Michael J. Birrer;Stephen T. Sawyer

  146
  Citations

• Vesicle trafficking plays a novel role in erythroblast enucleation

  Ganesan Keerthivasan;Sara Small;Hui Liu;Amittha Wickrema

  137
  Citations

• Differential requirements for survivin in hematopoietic cell development.

  Sandeep Gurbuxani;Yanfei Xu;Ganesan Keerthivasan;Amittha Wickrema

  132
  Citations

• Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors.

  Shahab Uddin;Samanthi Kottegoda;Danielle Stigger;Leonidas C. Platanias

  123
  Citations

• Engagement of Gab1 and Gab2 in Erythropoietin Signaling

  Amittha Wickrema;Shahab Uddin;Arun Sharma;Fei Chen

  123
  Citations