World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
92
Citations
27358
World Ranking
11419
National Ranking
5853

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Carlo Brugnara is affiliated with Boston Children's Hospital in the United States. Their work primarily spans the field of Medicine, with a focus on Genetics, Physiology, Hematology, Molecular Biology, and Immunology. The scientist has contributed extensively to topics related to hemoglobinopathies and related disorders, erythrocyte function and pathophysiology, iron metabolism and disorders, erythropoietin and anemia treatment, blood groups and transfusion, virus-based gene therapy research, and clinical laboratory practices and quality control.

Brugnara's recent publications illustrate the breadth of their research interests. Notable papers include:

  • Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome, 2021, published in Cell Host & Microbe
  • The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model, 2021, published in Journal of Clinical Investigation
  • Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations, 2021, published in Nature Immunology
  • An artificial intelligence-assisted diagnostic platform for rapid near-patient hematology, 2021, published in American Journal of Hematology
  • Using Reticulocyte Hemoglobin Equivalent as a Marker for Iron Deficiency and Responsiveness to Iron Therapy, 2021, published in Mayo Clinic Proceedings

The scientist frequently collaborates with other researchers. Some of their most common coauthors are Lucia De Franceschi, Alessandro Mattè, Enrica Federti, Achille Iolascon, and Angela Siciliano.

Brugnara has published extensively in several scientific journals. The most frequent publication venues include Blood, American Journal of Hematology, Haematologica, HemaSphere, and bioRxiv (Cold Spring Harbor Laboratory).

Throughout their career, Brugnara has been recognized as a member of the Association of American Physicians.

Best Publications

  • Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

    Adriana Donovan;Alison Brownlie;Alison Brownlie;Yi Zhou;Jennifer Shepard

  • Fetal Anemia and Apoptosis of Red Cell Progenitors in Stat5a−/−5b−/− Mice: A Direct Role for Stat5 in Bcl-XL Induction

    Merav Socolovsky;Amy E.J Fallon;Stream Wang;Carlo Brugnara

  • Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts.

    Merav Socolovsky;Hyung-song Nam;Mark D. Fleming;Volker H. Haase

  • Iron Deficiency and Erythropoiesis: New Diagnostic Approaches

    Carlo Brugnara

  • Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: Role of membrane oxidative damage

    Lucia De Franceschi;Giovanna Fattovich;Franco Turrini;Kodjo Ayi

  • Erythropoietin, iron, and erythropoiesis

    Lawrence T. Goodnough;Barry Skikne;Barry Skikne;Barry Skikne;Carlo Brugnara;Carlo Brugnara;Carlo Brugnara

  • Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.

    C Brugnara;L de Franceschi;S L Alper

  • Highly efficient therapeutic gene editing of human hematopoietic stem cells.

    Yuxuan Wu;Jing Zeng;Jing Zeng;Benjamin P. Roscoe;Pengpeng Liu

  • Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states

    Carlo Brugnara;B Schiller;J Moran

  • Reticulocyte Hemoglobin Content to Diagnose Iron Deficiency in Children

    Carlo Brugnara;David Zurakowski;James DiCanzio;Theonia Boyd

  • Use of recombinant human erythropoietin outside the setting of uremia

    Mario Cazzola;Francesco Mercuriali;Carlo Brugnara

  • Foxo3 is required for the regulation of oxidative stress in erythropoiesis

    Dragan Marinkovic;Xin Zhang;Safak Yalcin;Julia P. Luciano

  • Anion Exchanger 1 (Band 3) Is Required to Prevent Erythrocyte Membrane Surface Loss but Not to Form the Membrane Skeleton

    Luanne L Peters;Ramesh A Shivdasani;Shih-Chun Liu;Manjit Hanspal

  • Anemia in hemodialysis patients: variables affecting this outcome predictor.

    F Madore;E G Lowrie;C Brugnara;N L Lew

  • 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells.

    Osheiza Abdulmalik;Martin K. Safo;Qiukan Chen;Jisheng Yang

  • A novel method utilising markers of altered erythropoiesis for the detection of recombinant human erythropoietin abuse in athletes

    R Parisotto;CJ Gore;KR Emslie;MJ Ashenden

  • Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1

    Immacolata Andolfo;Seth L. Alper;Lucia De Franceschi;Carla Auriemma

  • Regulation of erythrocyte cation and water content in sickle cell anemia

    C Brugnara;HF Bunn;DC Tosteson

  • Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia

    A Brownlie;A Donovan;S J Pratt;B H Paw;B H Paw

  • Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.

    Carlo Brugnara;Beatrice Gee;Carrie C. Armsby;Susan Kurth

Frequent Co-Authors

Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Nader Rifai
Nader Rifai Boston Children's Hospital
Achille Iolascon
Achille Iolascon University of Naples Federico II
Yves Beuzard
Yves Beuzard University of Paris-Saclay
Mario Plebani
Mario Plebani University of Padua
Alan H.B. Wu
Alan H.B. Wu University of California, San Francisco
Wayne I. Lencer
Wayne I. Lencer Harvard University
Luanne L. Peters
Luanne L. Peters The Jackson Laboratory
Manoj T. Duraisingh
Manoj T. Duraisingh Harvard University
Anne Janin
Anne Janin Université Paris Cité

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