World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
9402
World Ranking
12826
National Ranking
996

Overview

Virgilio L. Lew is affiliated with the University of Cambridge in the United Kingdom. Their research spans across fields such as Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on Physiology, Pulmonary and Respiratory Medicine, Molecular Biology, Plant Science, and Pediatrics, Perinatology and Child Health.

The scientist's main areas of study include topics related to erythrocyte function and pathophysiology, blood properties and coagulation, neonatal health and biochemistry, hemoglobin structure and function, hemoglobinopathies and related disorders, as well as plant water relations and carbon dynamics and plant responses to elevated CO₂.

Virgilio L. Lew has contributed to several publications, including recent papers such as:

  • The circulatory dynamics of human red blood cell homeostasis: Oxy-deoxy and PIEZO1-triggered changes (2022, Biophysical Journal)
  • What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? (2021, Trends in Plant Science)
  • Guard cell endomembrane Ca2+-ATPases underpin a 'carbon memory' of photosynthetic assimilation that impacts on water-use efficiency (2021, Nature Plants)
  • PIEZO1 and the mechanism of the long circulatory longevity of human red blood cells (2021, PLoS Computational Biology)
  • Up-down biphasic volume response of human red blood cells to PIEZO1 activation during capillary transits (2021, PLoS Computational Biology)

Their frequent coauthors include Simon Rogers, Michael R. Blatt, Mareike Jezek, Adrian Hills, and Fernanda A. L. Silva-Alvim.

Virgilio L. Lew's research has been published primarily in venues such as:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Computational Biology
  • Trends in Plant Science
  • Nature Plants

Best Publications

  • Excess hemoglobin digestion and the osmotic stability ofPlasmodium falciparum–infected red blood cells

    Virgilio L. Lew;Teresa Tiffert;Hagai Ginsburg

  • Physiological [Ca2+]i level and pump-leak turnover in intact red cells measured using an incorporated Ca chelator.

    Virgilio L. Lew;Roger Y. Tsien;Roger Y. Tsien;Cristina Miner;Robert M. Bookchin

  • Calcium Transport and the Properties of a Calcium-Activated Potassium Channel in Red Cell Membranes

    Virgilio L. Lew;Hugo G. Ferreira

  • Volume, pH, and ion-content regulation in human red cells: Analysis of transient behavior with an integrated model

    Virgilio L. Lew;Virgilio L. Lew;Robert M. Bookchin;Robert M. Bookchin

  • Use of ionophore A23187 to measure cytoplasmic Ca buffering and activation of the Ca pump by internal Ca

    H. G. Ferreira;V. L. Lew

  • Membrane transport in red cells

    J. C. Ellory;Virgilio L. Lew

  • Ion Transport Pathology in the Mechanism of Sickle Cell Dehydration

    Virgilio L. Lew;Robert M. Bookchin

  • Inhibition of the calcium-induced increase in the potassium permeability of human red blood cells by quinine.

    Armando-Hardy M;Ellory Jc;Ferreira Hg;Fleminger S

  • Systems Dynamic Modeling of the Stomatal Guard Cell Predicts Emergent Behaviors in Transport, Signaling, and Volume Control

    Zhong-Hua Chen;Adrian Hills;Ulrike Bätz;Anna Amtmann

  • OnGuard, a Computational Platform for Quantitative Kinetic Modeling of Guard Cell Physiology

    Adrian Hills;Zhong-Hua Chen;Anna Amtmann;Michael R. Blatt

  • Evidence for a direct reticulocyte origin of dense red cells in sickle cell anemia.

    R M Bookchin;O E Ortiz;V L Lew

  • Variable Ca sensitivity of a K-selective channel in intact red-cell membranes

    V. L. Lew;H. G. Ferreira

  • Compartmentalization of sickle-cell calcium in endocytic inside-out vesicles

    Virgilio L. Lew;Austin Hockaday;Maria-Isabel Sepulveda;Andrew P. Somlyo

  • Stochastic nature and red cell population distribution of the sickling-induced Ca2+ permeability.

    V L Lew;O E Ortiz;R M Bookchin

  • Excess haemoglobin digestion by malaria parasites: a strategy to prevent premature host cell lysis.

    Virgilio L Lew;Lynn Macdonald;Hagai Ginsburg;Miriam Krugliak

  • Irreversible ATP depletion caused by low concentrations of formaldehyde and of calcium-chelator esters in intact human red cells

    Teresa Tiffert;Javier Garcia-Sancho;Virgilio L. Lew

  • Progressive inhibition of the Ca pump and Ca : Ca exchange in sickle red cells

    Robert M. Bookchin;Virgilio L. Lew

  • Properties of the Ca2+-activated K+ channel in one-step inside-out vesicles from human red cell membranes.

    Virgilio L. Lew;Shmuel Muallem;Carol A. Seymour

  • Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum

    Teresa Tiffert;Hagai Ginsburg;Miriam Krugliak;Barry C. Elford

  • Generation of normal human red cell volume, hemoglobin content, and membrane area distributions by "birth" or regulation?

    Virgilio L. Lew;Julia E. Raftos;Martin Sorette;Robert M. Bookchin

Frequent Co-Authors

Michael R. Blatt
Michael R. Blatt University of Glasgow
Javier García-Sancho
Javier García-Sancho Spanish National Research Council
Jeremy N. Skepper
Jeremy N. Skepper University of Cambridge
Hagai Ginsburg
Hagai Ginsburg Hebrew University of Jerusalem
Howard Griffiths
Howard Griffiths University of Cambridge
Tracy Lawson
Tracy Lawson University of Illinois at Urbana-Champaign
Zhong-Hua Chen
Zhong-Hua Chen University of Adelaide
Roger Y. Tsien
Roger Y. Tsien University of California, San Diego
Narla Mohandas
Narla Mohandas New York Blood Center
Anna Amtmann
Anna Amtmann University of Glasgow

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Virgilio L. Lew

Trending Scientists

Recently Published Articles