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Biology and Biochemistry

D-Index
73
Citations
14460
World Ranking
6082
National Ranking
53

Overview

Hagai Ginsburg is affiliated with the Hebrew University of Jerusalem in Israel and focuses research efforts primarily in the field of Medicine, with additional work in Immunology and Microbiology. The scientist's subfields of study include Public Health, Environmental and Occupational Health, Immunology, Virology, and Computational Theory and Mathematics.

Their research topics span several areas, notably:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • HIV Research and Treatment
  • Computational Drug Discovery Methods
  • Research on Leishmaniasis Studies

Recent publications highlight a concentration on the malaria parasite Plasmodium falciparum and its response to treatment resistance. Noteworthy papers include:

  • "Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response," 2022, Communications Biology
  • "The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response," 2021, Research Square (Research Square)

Frequent co-authors collaborating with Hagai Ginsburg across multiple publications include:

  • Rob W. van der Pluijm
  • Michal Kucharski
  • Sourav Nayak
  • Jaishree Tripathi
  • Nicholas J. White

The significant publication venues where the scientist's work appears are:

  • Communications Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)

Best Publications

  • Oxidative stress in malaria parasite-infected erythrocytes: Host-parasite interactions

    Katja Becker;Leann Tilley;Jonathan L. Vennerstrom;David Roberts

  • Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action.

    Hagai Ginsburg;Oleg Famin;Jianmin Zhang;Miriam Krugliak

  • Impairment of macrophage functions after ingestion of Plasmodium falciparum-infected erythrocytes or isolated malarial pigment.

    E Schwarzer;F Turrini;D Ulliers;G Giribaldi

  • Excess hemoglobin digestion and the osmotic stability ofPlasmodium falciparum–infected red blood cells

    Virgilio L. Lew;Teresa Tiffert;Hagai Ginsburg

  • Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins.

    Miriam Krugliak;Jianmin Zhang;Hagai Ginsburg

  • Origin of reactive oxygen species in erythrocytes infected with Plasmodium falciparum.

    Hani Atamna;Hagai Ginsburg

  • The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

    Zbynek Bozdech;Sachel Mok;Guangan Hu;Mallika Imwong

  • Susceptibility of human malaria parasites to chloroquine is pH dependent.

    A Yayon;Z I Cabantchik;H Ginsburg

  • Heme degradation in the presence of glutathione. A proposed mechanism to account for the high levels of non-heme iron found in the membranes of hemoglobinopathic red blood cells.

    Hani Atamna;Hagai Ginsburg

  • Characterization of permeation pathways appearing in the host membrane of Plasmodium falciparum infected red blood cells.

    H Ginsburg;S Kutner;M Krugliak;Z I Cabantchik

  • New permeability pathways induced in membranes of Plasmodium falciparum infected erythrocytes

    H Ginsburg;M Krugliak;O Eidelman;Z I Cabantchik

  • Characterization of permeation pathways in the plasma membrane of human erythrocytes infected with early stages of Plasmodium falciparum: Association with parasite development

    Kutner S;Breuer Wv;Ginsburg H;Aley Sb

  • A call for using natural compounds in the development of new antimalarial treatments- an introduction

    Hagai Ginsburg;Eric Deharo;Eric Deharo

  • Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum.

    Patrick G. Bray;Omar Janneh;Kaylene J. Raynes;Mathirut Mungthin

  • Phagocytosis of Plasmodium falciparum-infected human red blood cells by human monocytes: involvement of immune and nonimmune determinants and dependence on parasite developmental stage.

    F Turrini;H Ginsburg;F Bussolino;GP Pescarmona

  • The Malaria Parasite Supplies Glutathione to its Host Cell — Investigation of Glutathione Transport and Metabolism in Human Erythrocytes Infected with Plasmodium Falciparum

    Hani Atamna;Hagai Ginsburg

  • Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum

    Timothy G. Geary;James B. Jensen;H. Ginsburg

  • Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum.

    Avner Yayon;Rina Timberg;Shoshana Friedman;Hagai Ginsburg

  • The fate of ferriprotorphyrin IX in malaria infected erythrocytes in conjunction with the mode of action of antimalarial drugs.

    Jianmin Zhang;Miriam Krugliak;Hagai Ginsburg

  • Progress in in silico functional genomics: the malaria Metabolic Pathways database.

    Hagai Ginsburg

Frequent Co-Authors

Z. Ioav Cabantchik
Z. Ioav Cabantchik Hebrew University of Jerusalem
Wilfred D. Stein
Wilfred D. Stein Hebrew University of Jerusalem
Timothy G. Geary
Timothy G. Geary McGill University
Virgilio L. Lew
Virgilio L. Lew University of Cambridge
James B. Jensen
James B. Jensen Michigan State University
Avner Yayon
Avner Yayon Weizmann Institute of Science
Leann Tilley
Leann Tilley University of Melbourne
Abraham Loyter
Abraham Loyter Hebrew University of Jerusalem
Patrick G. Bray
Patrick G. Bray Liverpool School of Tropical Medicine
Kiaran Kirk
Kiaran Kirk Australian National University

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