World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
14091
World Ranking
8756
National Ranking
225

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Kiaran Kirk mainly focuses on Plasmodium falciparum, Biochemistry, Chloroquine, Drug resistance and Malaria. His Plasmodium falciparum study combines topics from a wide range of disciplines, such as ATPase, Red blood cell, Virology, Gene mutation and Vacuole. His study in the field of Extracellular, Cytosol, Intracellular and Membrane transport is also linked to topics like Pantothenic acid.

The concepts of his Cytosol study are interwoven with issues in Organelle and Cell biology. His Chloroquine study incorporates themes from Quinine and Integral membrane protein. His Drug resistance research focuses on Pharmacology and how it relates to Cell aging, Phenotypic screening and In vivo.

His most cited work include:

  • Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum (735 citations)
  • Membrane Transport in the Malaria-Infected Erythrocyte (347 citations)
  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. (257 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Plasmodium falciparum, Malaria, Extracellular and Membrane transport. His study in Plasmodium falciparum is interdisciplinary in nature, drawing from both In vitro, Virology, Efflux, Chloroquine and Pharmacology. His work carried out in the field of Chloroquine brings together such families of science as Quinine, Membrane transport protein, Gene mutation, Vacuole and Drug resistance.

Computational biology is closely connected to Drug discovery in his research, which is encompassed under the umbrella topic of Malaria. His Extracellular study combines topics in areas such as Amiloride, Membrane potential and Cell membrane. The various areas that Kiaran Kirk examines in his Membrane transport study include Red blood cell, Chloride channel, Biophysics, Cell biology and Na+/K+-ATPase.

He most often published in these fields:

  • Biochemistry (56.63%)
  • Plasmodium falciparum (56.63%)
  • Malaria (21.08%)

What were the highlights of his more recent work (between 2013-2021)?

  • Plasmodium falciparum (56.63%)
  • Biochemistry (56.63%)
  • Malaria (21.08%)

In recent papers he was focusing on the following fields of study:

Kiaran Kirk mainly investigates Plasmodium falciparum, Biochemistry, Malaria, Transporter and Efflux. His Plasmodium falciparum research incorporates themes from ATPase, Membrane transport, Membrane transport protein, Chloroquine and Pharmacology. His studies in Chloroquine integrate themes in fields like Drug resistance and Plasmodium berghei.

His research brings together the fields of Stereochemistry and Biochemistry. His studies deal with areas such as Genetics, Mechanism of action, Drug discovery and Microbiology as well as Malaria. His research investigates the connection between Transporter and topics such as Xenopus that intersect with issues in Mutation, Virology and In vitro.

Between 2013 and 2021, his most popular works were:

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. (257 citations)
  • (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium (144 citations)
  • Pyrazoleamide compounds are potent antimalarials that target Na + homeostasis in intraerythrocytic Plasmodium falciparum (78 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of investigation include Plasmodium falciparum, Malaria, Drug discovery, Biochemistry and Pharmacology. Kiaran Kirk has researched Plasmodium falciparum in several fields, including Membrane transport protein and Transporter. His work carried out in the field of Membrane transport protein brings together such families of science as Integral membrane protein, Intracellular parasite, Extracellular, Cell physiology and Membrane transport.

His biological study spans a wide range of topics, including Genetics and Drug resistance. His study in Cell biology extends to Biochemistry with its themes. His biological study deals with issues like Mechanism of action, which deal with fields such as ATPase, Ion homeostasis, Microbiology, Cytosol and Equivalent.

Best Publications

  • Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum.

    Michael B. Reed;Kevin J. Saliba;Sonia R. Caruana;Kiaran Kirk

  • Membrane Transport in the Malaria-Infected Erythrocyte

    Kiaran Kirk

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  • Chloroquine Transport via the Malaria Parasite’s Chloroquine Resistance Transporter

    Rowena E. Martin;Rosa V. Marchetti;Anna I. Cowan;Susan M. Howitt

  • Calothrixins A and B, novel pentacyclic metabolites from Calothrix cyanobacteria with potent activity against malaria parasites and human cancer cells

    Rodney W. Rickards;Jennifer M. Rothschild;Anthony C. Willis;Nola M. de Chazal

  • Transport of diverse substrates into malaria-infected erythrocytes via a pathway showing functional characteristics of a chloride channel.

    K Kirk;H A Horner;B C Elford;J C Ellory

  • Coenzyme A biosynthesis: an antimicrobial drug target.

    Christina Spry;Kiaran Kirk;Kevin J. Saliba

  • (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

    María Belén Jiménez-Díaz;Daniel Ebert;Yandira Salinas;Anupam Pradhan

  • Transport and Metabolism of the Essential Vitamin Pantothenic Acid in Human Erythrocytes Infected with the Malaria Parasite Plasmodium falciparum

    Kevin J. Saliba;Heather A. Horner;Kiaran Kirk

  • Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance.

    Patrick G. Bray;Rowena E. Martin;Leann Tilley;Stephen A. Ward

  • The Malaria Parasite's Chloroquine Resistance Transporter is a Member of the Drug/Metabolite Transporter Superfamily

    Rowena E. Martin;Kiaran Kirk

  • A surface transporter family conveys the trypanosome differentiation signal.

    Samuel Dean;Rosa Marchetti;Kiaran Kirk;Keith R. Matthews

  • Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

    Natalie J. Spillman;Richard J.W. Allen;Richard J.W. Allen;Case W. McNamara;Bryan K.S. Yeung

  • pH regulation in the intracellular malaria parasite, Plasmodium falciparum. H(+) extrusion via a V-type H(+)-ATPase.

    Kevin J. Saliba;Kiaran Kirk

  • The permeome of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum

    Rowena E Martin;Roselani I Henry;Janice L Abbey;John D Clements

  • Transport of organic substrates via a volume-activated channel.

    K Kirk;J C Ellory;J D Young

  • The pH of the digestive vacuole of Plasmodium falciparum is not associated with chloroquine resistance.

    Rhys Hayward;Kevin J. Saliba;Kiaran Kirk

  • Swelling-activated organic osmolyte channels.

    Kirk K

  • Pyrazoleamide compounds are potent antimalarials that target Na + homeostasis in intraerythrocytic Plasmodium falciparum

    Akhil B. Vaidya;Joanne M. Morrisey;Zhongsheng Zhang;Sudipta Das

  • Membrane transport in the malaria-infected erythrocyte

    R.E Martin;K.J Saliba;H.M Staines;K Kirk

Frequent Co-Authors

Stefan Bröer
Stefan Bröer Australian National University
Vicky M. Avery
Vicky M. Avery Griffith University
Elizabeth A. Winzeler
Elizabeth A. Winzeler University of California, San Diego
R. Kiplin Guy
R. Kiplin Guy University of Kentucky
David A. Fidock
David A. Fidock Columbia University
Susan A. Charman
Susan A. Charman Monash University
Sergio Wittlin
Sergio Wittlin Swiss Tropical and Public Health Institute
Guri Giaever
Guri Giaever University of British Columbia
Corey Nislow
Corey Nislow University of British Columbia
Patrick G. Bray
Patrick G. Bray Liverpool School of Tropical Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Kiaran Kirk

Trending Scientists

Recently Published Articles