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Biology and Biochemistry

D-Index
65
Citations
14885
World Ranking
9161
National Ranking
4063

Overview

Manuel Llinás is affiliated with Pennsylvania State University in the United States. Their research primarily focuses on Medicine and Immunology and Microbiology, with significant contributions to Public Health, Environmental and Occupational Health, Molecular Biology, Immunology, Infectious Diseases, and Epidemiology.

The scientist's work spans important topics including Malaria Research and Control, Invertebrate Immune Response Mechanisms, HIV/AIDS drug development and treatment, Mosquito-borne diseases and control, Trypanosoma species research and implications, HIV Research and Treatment, and Insect Resistance and Genetics.

Manuel Llinás has published extensively in various scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • PLoS Pathogens
  • Nature Microbiology
  • Nature Medicine

Recent papers authored or co-authored by Llinás cover a range of topics in malaria research and related fields:

  • Dissecting the role of PfAP2-G in malaria gametocytogenesis (2020), Nature Communications
  • Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival (2021), Nature Communications
  • Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season (2020), Nature Medicine
  • MalDA, Accelerating Malaria Drug Discovery (2021), Trends in Parasitology
  • Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq (2020), BMC Genomics

Frequent collaborators in their research include Lindsey Orchard, David A. Fidock, Jacquin C. Niles, Justin Munro, and Charisse Flerida A. Pasaje. Collaboration with these researchers has contributed to multiple scientific outputs.

Best Publications

  • The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum

    Zbynek Bozdech;Manuel Llinás;Brian Lee Pulliam;Edith D Wong

  • A transcriptional switch underlies commitment to sexual development in malaria parasites.

    Björn F. C. Kafsack;Núria Rovira-Graells;Taane G. Clark;Cristina Bancells

  • New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq

    Thomas D. Otto;Daniel Wilinski;Sammy Assefa;Thomas M. Keane

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  • Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains

    Manuel Llinás;Zbynek Bozdech;Edith D. Wong;Alex T. Adai

  • A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium

    Abhinav Sinha;Katie R. Hughes;Katarzyna K. Modrzynska;Thomas D. Otto

  • Host-parasite interactions revealed by Plasmodium falciparum metabolomics.

    Kellen L. Olszewski;Joanne M. Morrisey;Daniel Wilinski;James M. Burns

  • Sexual development in Plasmodium parasites: knowing when it's time to commit

    Gabrielle A. Josling;Manuel Llinás

  • Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite

    Tracey L. Campbell;Erandi K. De Silva;Kellen L. Olszewski;Olivier Elemento

  • Specific DNA-binding by Apicomplexan AP2 transcription factors

    Erandi K. De Silva;Andrew R. Gehrke;Kellen Olszewski;Ilsa León

  • Solution structure of Syrian hamster prion protein rPrP(90-231).

    He Liu;Shauna Farr-Jones;Nikolai B. Ulyanov;Manuel Llinas

  • A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion

    Bradley I. Coleman;Kristen M. Skillman;Rays H.Y. Jiang;Lauren M. Childs

  • Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

    Annie N. Cowell;Eva S. Istvan;Amanda K. Lukens;Amanda K. Lukens;Maria G. Gomez-Lorenzo

  • The Apicomplexan AP2 family: Integral factors regulating Plasmodium development

    Heather J. Painter;Tracey L. Campbell;Manuel Llinás

  • Nutrient sensing modulates malaria parasite virulence

    Liliana Mancio-Silva;Ksenija Slavic;Margarida T. Grilo Ruivo;Ana Rita Grosso

  • Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.

    Judith Straimer;Marcus C S Lee;Andrew H Lee;Bryan Zeitler

  • Genetic Investigation of Tricarboxylic Acid Metabolism during the Plasmodium falciparum Life Cycle

    Hangjun Ke;Ian A. Lewis;Joanne M. Morrisey;Kyle J. McLean

  • Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state

    Shalon E Babbitt;Lindsey Altenhofen;Simon A Cobbold;Eva S Istvan

  • Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum

    Kellen L. Olszewski;Michael W. Mather;Joanne M. Morrisey;Benjamin A. Garcia

  • Reconstruction and flux‐balance analysis of the Plasmodium falciparum metabolic network

    Germán Plata;Tzu Lin Hsiao;Kellen L. Olszewski;Manuel Llinás

Frequent Co-Authors

Elizabeth A. Winzeler
Elizabeth A. Winzeler University of California, San Diego
David A. Fidock
David A. Fidock Columbia University
Dyann F. Wirth
Dyann F. Wirth Harvard University
Kelly Chibale
Kelly Chibale University of Cape Town
Daniel E. Goldberg
Daniel E. Goldberg Washington University in St. Louis
Oliver Billker
Oliver Billker Umeå University
Akhil B. Vaidya
Akhil B. Vaidya Drexel University
Joseph L. DeRisi
Joseph L. DeRisi University of California, San Francisco
Thomas D. Otto
Thomas D. Otto University of Glasgow
Kirk W. Deitsch
Kirk W. Deitsch Cornell University

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