Balbino Alarcón spends much of his time researching T-cell receptor, Cell biology, T cell, Signal transduction and CD3. His work carried out in the field of T-cell receptor brings together such families of science as Molecular biology, Biochemistry and Major histocompatibility complex, Antigen. The various areas that Balbino Alarcón examines in his Cell biology study include Immunological synapse, Internalization and Antigen-presenting cell.
Specifically, his work in T cell is concerned with the study of Jurkat cells. His biological study spans a wide range of topics, including Thymocyte, Transgene and Phosphorylation. His CD3 research includes themes of Cytoplasm, Biophysics, Conformational change, Protein subunit and Protein structure.
Balbino Alarcón mainly investigates T-cell receptor, Cell biology, T cell, Molecular biology and Receptor. His T-cell receptor research incorporates elements of Jurkat cells, Major histocompatibility complex, Antigen, Signal transduction and CD3. His Cell biology research is multidisciplinary, incorporating perspectives in Antigen-presenting cell, Immunological synapse, Conformational change, Biochemistry and Internalization.
The T cell study combines topics in areas such as Cytotoxic T cell, Transgene and Tyrosine phosphorylation. His Molecular biology research integrates issues from Phenotype, CD8 and Virology. The Receptor study which covers Cell that intersects with Extracellular.
Balbino Alarcón mostly deals with Cell biology, Antigen, T cell, T-cell receptor and Antibody. In his research, Balbino Alarcón undertakes multidisciplinary study on Cell biology and Vimentin. The study incorporates disciplines such as Cell, Cytotoxic T cell, B-cell receptor and Germinal center in addition to Antigen.
His T cell study integrates concerns from other disciplines, such as Proinflammatory cytokine and Cellular differentiation. His research in T-cell receptor intersects with topics in Transcription, Biophysics, Ceramide and Major histocompatibility complex. His Major histocompatibility complex research includes elements of CD3 Complex, Endosome, Signal transduction, Endocytosis and Binding site.
His primary areas of investigation include T-cell receptor, Cell biology, Antigen, Biophysics and T cell. His studies deal with areas such as Major histocompatibility complex and Endosome as well as T-cell receptor. His Cell biology study incorporates themes from Immunoglobulin class switching, Antibody, Germinal center and Vaccination.
Balbino Alarcón interconnects B cell, IL-2 receptor, CD40 and Antigen-presenting cell in the investigation of issues within Antigen. As part of the same scientific family, Balbino Alarcón usually focuses on Biophysics, concentrating on Phosphorylation and intersecting with CD3, Multiprotein complex, Ligand, Receptor and Cell surface receptor. His research in T cell intersects with topics in Membrane cholesterol, Biochemistry, Signal transduction and Endocytosis.
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The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble
Hans Clevers;Balbino Alarcon;Thomas Wileman;Cox Terhorst.
Annual Review of Immunology (1988)
Recruitment of Nck by CD3ϵ Reveals a Ligand-Induced Conformational Change Essential for T Cell Receptor Signaling and Synapse Formation
Diana Gil;Wolfgang W.A. Schamel;Marı́a Montoya;Francisco Sánchez-Madrid.
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response.
Wolfgang W.A. Schamel;Ignacio Arechaga;Ruth M. Risueño;Hisse M. van Santen.
Journal of Experimental Medicine (2005)
CD3δ deficiency arrests development of the αβ but not the γδ T cell lineage
Vibhuti P. Dave;Zhensheng Cao;Carol Browne;Balbino Alarcon.
The EMBO Journal (1997)
Full activation of the T cell receptor requires both clustering and conformational changes at CD3.
Susana Minguet;Mahima Swamy;Balbino Alarcón;Immanuel F. Luescher.
Polysaccharides as antiviral agents: antiviral activity of carrageenan.
M. E González;Balbino Alarcón;Luís Carrasco.
Antimicrobial Agents and Chemotherapy (1987)
MTOC translocation modulates IS formation and controls sustained T cell signaling.
Noa B. Martín-Cófreces;Javier Robles-Valero;J. Román Cabrero;María Mittelbrunn;María Mittelbrunn.
Journal of Cell Biology (2008)
Multivalent structure of an αβT cell receptor
Gemma Fernández-Miguel;Balbino Alarcón;Antonio Iglesias;Horst Bluethmann.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Internalization and intracellular fate of TCR-CD3 complexes.
Andres Alcover;Balbino Alarcon.
Critical Reviews in Immunology (2000)
Increased Sensitivity of Antigen-Experienced T Cells through the Enrichment of Oligomeric T Cell Receptor Complexes
Rashmi Kumar;María Ferez;Mahima Swamy;Ignacio Arechaga.
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