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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Immunology

D-Index
95
Citations
32082
World Ranking
900
National Ranking
56

Molecular Biology

D-Index
95
Citations
32056
World Ranking
635
National Ranking
53

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2018 - Member of the National Academy of Sciences
  • 2014 - Paul Ehrlich and Ludwig Darmstaedter Prize
  • 2006 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Michael Reth is affiliated with the University of Freiburg in Germany and conducts research primarily in the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology.

Their research focuses on immunological processes, with an emphasis on T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, Monoclonal and Polyclonal Antibodies Research, HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, and Glycosylation and Glycoproteins Research.

Michael Reth has published extensively in various scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Proceedings of the National Academy of Sciences
  • Life Science Alliance
  • Research Square (Research Square)

Recent papers authored or coauthored by Michael Reth cover multiple aspects of B cell biology and antigen receptor function:

  • "Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications" (2020), published in Annals of the Rheumatic Diseases
  • "CD20 as a gatekeeper of the resting state of human B cells" (2021), published in Proceedings of the National Academy of Sciences
  • "Structural principles of B cell antigen receptor assembly" (2022), published in Nature
  • "Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation" (2022), published in Science Advances
  • "Plasma membrane topography governs the 3D dynamic localization of IgM B cell antigen receptor clusters" (2023), published in The EMBO Journal

Michael Reth collaborates regularly with a number of researchers in the field. Frequent co-authors include:

  • Kathrin Kläsener
  • Deniz Saltukoglu
  • Kara Anasti
  • Julia Jellusova
  • Jianying Yang

Their contributions to the scientific community have been recognized through several awards and honors:

  • Member of the National Academy of Sciences (2018)
  • Paul Ehrlich and Ludwig Darmstaedter Prize (2014)
  • Membership in the German National Academy of Sciences Leopoldina for Microbiology and Immunology (2006)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Antigen receptor tail clue.

    Michael Reth

  • Postnatal isl1 + cardioblasts enter fully differentiated cardiomyocyte lineages

    Karl Ludwig Laugwitz;Alessandra Moretti;Jason Lam;Peter Gruber

  • Hydrogen peroxide as second messenger in lymphocyte activation.

    Michael Reth

  • Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.

    Alfred L.M. Bothwell;Michael Paskind;Michael Reth;Thereza Imanishi-Kari

  • Fundamental properties of unperturbed haematopoiesis from stem cells in vivo

    Katrin Busch;Kay Klapproth;Melania Barile;Michael Flossdorf

  • Antigen Receptors on B Lymphocytes

    Michael Reth

  • Testing gene function early in the B cell lineage in mb1-cre mice

    E. Hobeika;S. Thiemann;B. Storch;H. Jumaa

  • Initiation and processing of signals from the B cell antigen receptor.

    Michael Reth;J. Wienands

  • Molecular components of the B-cell antigen receptor complex of the IgM class

    Joachim Hombach;Takeshi Tsubata;Lise Leclercq;Heike Stappert

  • Regulation of genome rearrangement events during lymphocyte differentiation.

    F W Alt;T K Blackwell;R A DePinho;M G Reth

  • Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

    Yoshiteru Sasaki;Emmanuel Derudder;Elias Hobeika;Roberta Pelanda

  • Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.

    Véronique Rolli;Maike Gallwitz;Thomas Wossning;Alexandra Flemming

  • Inducible site-directed recombination in mouse embryonic stem cells.

    Yong Zhang;Christa Riesterer;Anne-Marie Ayrall;Fred Sablitzky

  • A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production.

    Michael Reth;Peter Gehrmann;Eva Petrac;Petra Wiese

  • Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling

    Sebastian Herzog;Michael Reth;Hassan Jumaa

  • Analysis of the repertoire of anti‐NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

    M. Reth;G. J. Hämmerling;K. Rajewsky

  • Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.

    Kaoru Saijo;Christian Schmedt;I-hsin Su;Hajime Karasuyama

  • Monomeric and oligomeric complexes of the B cell antigen receptor.

    Wolfgang W.A Schamel;Michael Reth

  • Aberrant B cell development and immune response in mice with a compromised BCR complex.

    Raul M. Torres;Heinrich Flaswinkel;Michael Reth;Klaus Rajewsky

  • Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65.

    Hassan Jumaa;Bernd Wollscheid;Michael Mitterer;Jürgen Wienands

Frequent Co-Authors

Hassan Jumaa
Hassan Jumaa Max Planck Society
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Jürgen Wienands
Jürgen Wienands University of Göttingen
Wolfgang W. A. Schamel
Wolfgang W. A. Schamel University of Freiburg
Michael Huber
Michael Huber University of Zurich
Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Lars Nitschke
Lars Nitschke University of Erlangen-Nuremberg
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Garnett Kelsoe
Garnett Kelsoe Duke University

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