His primary areas of investigation include Cancer research, Leukemia, Immunology, B cell and Myeloid leukemia. His Cancer research research is multidisciplinary, relying on both Cancer, Tyrosine kinase, Receptor, Signal transduction and B-cell receptor. His Leukemia study incorporates themes from Randomized controlled trial, Drug resistance, Oncology and Lymphoma.
His research investigates the connection with B cell and areas like Cell cycle which intersect with concerns in Philadelphia chromosome. His Myeloid leukemia research includes themes of Beta-catenin, Wnt signaling pathway, Catenin, Coactivator and EP300. His Somatic hypermutation research incorporates themes from Suppressor, Germinal center, Mutation frequency, Molecular biology and DNA repair.
Markus Müschen mostly deals with Cancer research, Leukemia, B cell, Molecular biology and Immunology. His Cancer research research incorporates elements of BCL6, Tyrosine kinase, breakpoint cluster region and Acute lymphocytic leukemia. The study incorporates disciplines such as Myeloid, Progenitor cell, Stem cell, Myeloid leukemia and Bone marrow in addition to Leukemia.
His work deals with themes such as Signal transduction and Cell biology, which intersect with B cell. His Cell biology research integrates issues from Transcription factor and Cellular differentiation. He combines subjects such as Activation-induced deaminase and Genetics, Gene rearrangement, Gene with his study of Molecular biology.
Cancer research, B cell, Cell biology, Leukemia and Signal transduction are his primary areas of study. His Cancer research research includes themes of Cancer, breakpoint cluster region, Chronic lymphocytic leukemia and Lymphoma. The various areas that he examines in his B cell study include Cell culture and Receptor.
The Cell biology study combines topics in areas such as Oncogenic signaling, Transcription factor, Germinal center, Pentose phosphate pathway and Transformation. His research integrates issues of LILRB4, Myeloid leukemia and Synthetic lethality in his study of Leukemia. His Signal transduction study combines topics from a wide range of disciplines, such as Mutation, Cell cycle checkpoint, Cytokine and Phosphorylation.
The scientist’s investigation covers issues in Cancer research, Leukemia, Transcription factor, Regulation of gene expression and B cell. His study in Cancer research focuses on Myeloid leukemia in particular. His work carried out in the field of Leukemia brings together such families of science as Immune checkpoint, Demethylase, Cancer stem cell, LILRB4 and Cytotoxicity.
His Transcription factor research is multidisciplinary, incorporating elements of Malignant transformation, Chromatin immunoprecipitation, BCL6 and Germline. His studies in Regulation of gene expression integrate themes in fields like Gene knockdown, Activation-induced deaminase, Cytidine deaminase, Immunology and Transcription. His research in B cell intersects with topics in Phage display, Lymphoma, Immune system and Cell biology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential
Gesine Kögler;Sandra Sensken;Judith A. Airey;Thorsten Trapp.
Journal of Experimental Medicine (2004)
Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia
Rongqing Pan;Leah J. Hogdal;Juliana M. Benito;Donna Bucci.
Cancer Discovery (2014)
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species
Maria Wartenberg;Frederike C. Ling;Markus Müschen;Florian Klein.
The FASEB Journal (2003)
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
Elli Papaemmanuil;Inmaculada Rapado;Yilong Li;Nicola E Potter.
Nature Genetics (2014)
Rare Occurrence of Classical Hodgkin's Disease as a T Cell Lymphoma
Markus Müschen;Klaus Rajewsky;Andreas Bräuninger;Audrey Sylvia Baur.
Journal of Experimental Medicine (2000)
Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction.
Markus Müschen;Daniel Re;Berit Jungnickel;Volker Diehl.
Journal of Experimental Medicine (2000)
Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for their Lineage and Stage Specificity
Albert G. Tsai;Haihui Lu;Sathees C. Raghavan;Markus Muschen.
A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance.
R Josien;P Douillard;C Guillot;M Müschen.
Journal of Clinical Investigation (1998)
Oct-2 and Bob-1 deficiency in Hodgkin and Reed Sternberg cells.
Daniel Re;Markus Müschen;Tahamtan Ahmadi;Claudia Wickenhauser.
Cancer Research (2001)
BCL6 enables Ph + acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition
Cihangir Duy;Christian Hurtz;Christian Hurtz;Seyedmehdi Shojaee;Leandro Cerchietti.
Profile was last updated on December 6th, 2021.
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