Ralf Küppers

Overview

Best Publications

• The landscape of genomic alterations across childhood cancers

  Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  1562
  Citations

• Mechanisms of B-cell lymphoma pathogenesis

  Ralf Küppers

  1312
  Citations

• Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

  Laura Pasqualucci;Peter Neumeister;Tina Goossens;Gouri Nanjangud

  1306
  Citations

• Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells

  Ulf Klein;Klaus Rajewsky;Ralf Küppers

  1177
  Citations

• Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

  H Kanzler;R Küppers;M L Hansmann;K Rajewsky

  1010
  Citations

• Cellular Origin of Human B-Cell Lymphomas

  Ralf Küppers;Ulf Klein;Martin-Leo Hansmann;Klaus Rajewsky

  950
  Citations

• Patterns of somatic structural variation in human cancer genomes

  Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  942
  Citations

• Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.

  Ralf Kuppers;Klaus Rajewsky;Min Zhao;Gunther Simons

  936
  Citations

• Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections.

  R. Küppers;Min Zhao;M.-L. Hansmann;K. Rajewsky

  872
  Citations

• Mechanisms of chromosomal translocations in B cell lymphomas.

  Ralf Küppers;Ralf Küppers;Riccardo Dalla-Favera

  871
  Citations

• The biology of Hodgkin's lymphoma.

  Ralf Küppers

  858
  Citations

• From pathogenesis to treatment of chronic lymphocytic leukaemia

  Thorsten Zenz;Daniel Mertens;Ralf Küppers;Hartmut Döhner

  774
  Citations

• B cells under influence: transformation of B cells by Epstein–Barr virus

  Ralf Küppers

  743
  Citations

• BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci

  Laura Pasqualucci;Anna Migliazza;Nicola Fracchiolla;Christopher William

  622
  Citations

• TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

  Roland Schmitz;Martin-Leo Hansmann;Verena Bohle;Jose Ignacio Martin-Subero

  563
  Citations

• Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma.

  Ines Schwering;Andreas Bräuninger;Ulf Klein;Berit Jungnickel

  495
  Citations

• Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

  Julia Richter;Matthias Schlesner;Steve Hoffmann;Markus Kreuz

  474
  Citations

• Somatic hypermutation in normal and transformed human B cells

  U Klein;T Goossens;M Fischer;H Kanzler

  435
  Citations

• Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease

  Tina Goossens;Ulf Klein;Ralf Küppers

  434
  Citations

• THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

  Ralf Küppers;Klaus Rajewsky

  421
  Citations