World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
36955
World Ranking
4437
National Ranking
2155

Research.com Recognitions

  • 2006 - Fellow of Alfred P. Sloan Foundation

Overview

Thomas G. Graeber is affiliated with the University of California, Los Angeles in the United States. Their research spans across biochemistry, genetics, molecular biology, and medicine, with a considerable focus on molecular biology and cancer-related fields.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of study reveal a specialized focus on:

  • Molecular Biology
  • Cancer Research
  • Oncology
  • Immunology
  • Genetics

Their work addresses topics related to cancer biology, metabolism, and genomics. Central themes in their research include:

  • Cancer, Hypoxia, and Metabolism
  • Cancer Genomics and Diagnostics
  • Cancer, Lipids, and Metabolism
  • RNA modifications and cancer
  • Lung Cancer Research Studies
  • Glioma Diagnosis and Treatment
  • Melanoma and MAPK Pathways

Graeber has contributed to various publication venues with frequent appearances in:

  • Neuro-Oncology
  • SSRN Electronic Journal
  • AEA Randomized Controlled Trials
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research

Among their recent papers are:

  • CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis (2023), Cancer Cell
  • Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity (2020), JCI Insight
  • Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti-PD-1 therapy (2021), Journal of Clinical Investigation
  • Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation (2023), Cancer Cell
  • Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma (2023), Signal Transduction and Targeted Therapy

They have collaborated often with the following researchers:

  • Nicholas Bayley
  • Timothy F. Cloughesy
  • Linda M. Liau
  • David A. Nathanson
  • Johanna ten Hoeve

In 2006, Graeber was recognized as a Fellow of the Alfred P. Sloan Foundation, indicating a notable milestone in their academic career.

Best Publications

  • Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

    Jesse M. Zaretsky;Angel Garcia-Diaz;Daniel S. Shin;Helena Escuin-Ordinas

  • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

    Thomas G. Graeber;Cynthia Osmanian;Tyler Jacks;David E. Housman

  • Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

    Jason Lloyd-Price;Jason Lloyd-Price;Cesar Arze;Ashwin N. Ananthakrishnan;Melanie Schirmer;Melanie Schirmer

  • RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

    Poulikos I. Poulikakos;Yogindra Persaud;Manickam Janakiraman;Xiangju Kong

  • Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.

    Angel Garcia-Diaz;Daniel Sanghoon Shin;Blanca Homet Moreno;Justin Saco

  • An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

    Dan Rohle;Janeta Popovici-Muller;Nicolaos Palaskas;Sevin Turcan

  • Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations.

    Daniel Sanghoon Shin;Jesse M. Zaretsky;Helena Escuin-Ordinas;Angel Garcia-Diaz

  • Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

    Katharine Ellwood-Yen;Thomas G. Graeber;John Wongvipat;M. Luisa Iruela-Arispe

  • Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

    T G Graeber;J F Peterson;M Tsai;K Monica

  • Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress.

    Jennifer Tsoi;Lidia Robert;Kim Paraiso;Carlos Galvan

  • Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.

    Judith Müller;Oscar Krijgsman;Jennifer Tsoi;Lidia Robert

  • Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

    David J. Mulholland;Linh M. Tran;Yunfeng Li;Houjian Cai

  • Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

    Yoko Kidani;Heidi Elsaesser;M Benjamin Hock;M Benjamin Hock;Laurent Vergnes

  • TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

    Stephan R Krutzik;Belinda Tan;Huiying Li;Maria Teresa Ochoa

  • Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.

    Siwen Hu-Lieskovan;Stephen Mok;Blanca Homet Moreno;Blanca Homet Moreno;Jennifer Tsoi

  • Rank–rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures

    Seema B. Plaisier;Richard Taschereau;Justin A. Wong;Thomas G. Graeber

  • Type I Interferon Suppresses Type II Interferon–Triggered Human Anti-Mycobacterial Responses

    Rosane M. B. Teles;Thomas G. Graeber;Stephan R. Krutzik;Dennis Montoya

  • Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor

    Abigail S. Krall;Shili Xu;Thomas G. Graeber;Daniel Braas

  • CTLA4 blockade broadens the peripheral T cell receptor repertoire

    Lidia Robert;Jennifer Tsoi;Xiaoyan Wang;Ryan O. Emerson

  • Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma.

    Christian Grommes;Christian Grommes;Alessandro Pastore;Nicolaos Palaskas;Sarah S Tang

Frequent Co-Authors

Antoni Ribas
Antoni Ribas University of California, Los Angeles
Markus Müschen
Markus Müschen Yale University
Ingo K. Mellinghoff
Ingo K. Mellinghoff Memorial Sloan Kettering Cancer Center
Owen N. Witte
Owen N. Witte University of California, Los Angeles
Amato J. Giaccia
Amato J. Giaccia Stanford University
Jiaoti Huang
Jiaoti Huang Duke University
Hsian-Rong Tseng
Hsian-Rong Tseng University of California, Los Angeles
Ari Melnick
Ari Melnick Cornell University
Jonathan Braun
Jonathan Braun Cedars-Sinai Medical Center
Hong Wu
Hong Wu Peking University

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