World's Best Scientists 2026 revealed!
Award Badge
Biology and Biochemistry
China
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
112
Citations
44289
World Ranking
903
National Ranking
16

Medicine

D-Index
110
Citations
43870
World Ranking
5574
National Ranking
54

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in China Leader Award
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Hong Wu is affiliated with Peking University in China and has a research focus primarily in Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans several subfields, including Molecular Biology, Oncology, Cancer Research, Immunology, and Pulmonary and Respiratory Medicine.

Their research topics cover a range of areas related to cancer and cellular mechanisms. Key themes include:

  • Cancer-related Molecular Pathways
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Cancer-related molecular mechanisms research
  • Acute Lymphoblastic Leukemia research
  • Cell death mechanisms and regulation
  • Cancer, Hypoxia, and Metabolism

Among recent publications, notable papers include:

  • "DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities" (2022), published in Experimental & Molecular Medicine
  • "TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism" (2020), published in Nature Communications
  • "Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment" (2022), published in Nature Communications
  • "Nonbone Marrow CD34 + Cells Are Crucial for Endothelial Repair of Injured Artery" (2021), published in Circulation Research
  • "Regulation of the tumor suppressor PTEN in triple-negative breast cancer" (2021), published in Cancer Letters

Hong Wu frequently publishes in several scientific venues, including:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Experimental & Molecular Medicine
  • Cancer Letters
  • Frontiers in Pharmacology

The scientist has collaborated often with colleagues such as Roger Leng, Consolato Sergi, Haichuan Zhu, Yasser Abuetabh, and Lu Yang, reflecting a network of frequent coauthors.

Hong Wu has received recognition as a Fellow of the American Association for the Advancement of Science (AAAS), awarded in 2010.

Best Publications

  • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

    Ömer H. Yilmaz;Riccardo Valdez;Brian K. Theisen;Wei Guo

  • Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

    Shunyou Wang;Jing Gao;Qunying Lei;Nora Rozengurt

  • Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

    Hong Wu;Xin Liu;Rudolf Jaenisch;Harvey F. Lodish

  • Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11

    Katharina Schlacher;Nicole Christ;Nicolas Siaud;Akinori Egashira

  • Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR

    Mehran S. Neshat;Ingo K. Mellinghoff;Chris Tran;Bangyan Stiles

  • Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity

    Wen Hong Shen;Adayabalam S. Balajee;Jianli Wang;Hong Wu

  • Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis

    Hans Neubauer;Ana Cumano;Mathias Müller;Hong Wu

  • PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

    Hong Sun;Ralf Lesche;Da-Ming Li;Joanna Liliental

  • Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo

    Matthias Groszer;Rebecca Erickson;Deirdre D. Scripture-Adams;Ralf Lesche

  • PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

    Jiwang Zhang;Justin C. Grindley;Tong Yin;Sachintha Jayasinghe

  • A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

    Katharina Schlacher;Hong Wu;Maria Jasin

  • Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

    Janel E. Le Belle;Nicolas M. Orozco;Andres A. Paucar;Jonathan P. Saxe

  • Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

    S. Horvath;B. Zhang;M. Carlson;K. V. Lu

  • Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

    Xin Liu;Hong Wu;Michael Byrne;Stephen Krane

  • PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

    Daniel J. Freeman;Andrew G. Li;Gang Wei;Heng-Hong Li

  • Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells.

    Shutao Wang;Hao Wang;Jing Jiao;Kuan-Ju Chen

  • Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

    David J. Mulholland;Linh M. Tran;Yunfeng Li;Houjian Cai

  • Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells

    David J. Mulholland;Naoko Kobayashi;Marcus Ruscetti;Allen Zhi

  • PTEN-deficient intestinal stem cells initiate intestinal polyposis.

    Xi C He;Tong Yin;Justin C Grindley;Qiang Tian

  • Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

    Bangyan Stiles;Ying Wang;Andreas Stahl;Sara Bassilian

Frequent Co-Authors

Owen N. Witte
Owen N. Witte University of California, Los Angeles
Ingo K. Mellinghoff
Ingo K. Mellinghoff Memorial Sloan Kettering Cancer Center
Paul S. Mischel
Paul S. Mischel Stanford University
Weilong Guo
Weilong Guo China Agricultural University
Thomas G. Graeber
Thomas G. Graeber University of California, Los Angeles
Peter S. Nelson
Peter S. Nelson Fred Hutchinson Cancer Research Center
Stephen M. Krane
Stephen M. Krane Harvard University
Ursula Klingmüller
Ursula Klingmüller German Cancer Research Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to a variety of online degrees and rewarding career pathways in healthcare and life sciences. Graduates often consider specialized certifications and advanced degrees to enhance their skills and career prospects.

For those interested in nursing, there are accelerated and best online post master's pmhnp programs for Psychiatric Mental Health Nurse Practitioners, as well as the shortest post master's fnp program for Family Nurse Practitioners. Both are excellent options for biology or biochemistry graduates looking to expand into advanced nursing practice roles.

Nutrition and dietetics is another fast-growing area. Many choose the cheapest online nutrition degree to efficiently gain credentials for careers focused on health, wellness, and nutrition.

If you are a registered nurse considering further education, the cheapest rn to bsn online options can provide a streamlined path toward career advancement and higher earning potential in clinical and research roles.

With flexible online formats, these programs allow students to build upon their background in biology or biochemistry and access new professional opportunities while balancing work and life.

Best Scientists Citing Hong Wu

Trending Scientists

Recently Published Articles