World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
111
Citations
104965
World Ranking
916
National Ranking
572

Medicine

D-Index
111
Citations
104965
World Ranking
5215
National Ranking
2817

Overview

Sean J. Morrison is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans the fields of biochemistry, genetics, and molecular biology, alongside significant contributions to medicine. The scientist's work focuses on several subfields, including molecular biology, cancer research, hematology, genetics, and immunology.

Their research interests cover a range of main topics, prominently featuring cancer, hypoxia, and metabolism; hematopoietic stem cell transplantation; mesenchymal stem cell research; epigenetics and DNA methylation; RNA modifications and cancer; single-cell and spatial transcriptomics; and pluripotent stem cells research.

Sean J. Morrison has authored numerous papers published in high-impact journals. Notable recent publications include:

  • Lymph protects metastasizing melanoma cells from ferroptosis, 2020, Nature
  • A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis, 2021, Nature
  • Niches that regulate stem cells and hematopoiesis in adult bone marrow, 2021, Developmental Cell
  • Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair, 2022, Cell Stem Cell
  • PHGDH heterogeneity potentiates cancer cell dissemination and metastasis, 2022, Nature

Frequently, this scientist collaborates with other researchers, including Zhiyu Zhao, Thomas P. Mathews, Alpaslan Tasdogan, Andrew DeVilbiss, and Misty S. Martin-Sandoval, with collaboration counts ranging from 12 to 33 joint works.

Sean J. Morrison's work appears regularly in several publication venues. The most frequent outlets for their publications are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Nature
  • Cell Stem Cell
  • Cancer Research

Best Publications

  • Prospective identification of tumorigenic breast cancer cells

    Muhammad Al-Hajj;Max S. Wicha;Adalberto Benito-Hernandez;Sean J. Morrison;Sean J. Morrison

  • Stem cells, cancer, and cancer stem cells

    Tannishtha Reya;Tannishtha Reya;Sean J. Morrison;Michael F. Clarke;Irving L. Weissman

  • SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

    Mark J. Kiel;Ömer H. Yilmaz;Toshihide Iwashita;Osman H. Yilmaz

  • Tumour heterogeneity and cancer cell plasticity

    Corbin E. Meacham;Sean J. Morrison

  • The bone marrow niche for haematopoietic stem cells

    Sean J. Morrison;David T. Scadden

  • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.

    In Kyung Park;Dalong Qian;Mark Kiel;Michael W. Becker

  • Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

    Sean J. Morrison;Allan C. Spradling

  • Efficient tumour formation by single human melanoma cells

    Elsa Quintana;Mark Shackleton;Michael S. Sabel;Douglas R. Fullen

  • Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

    Manuel Alvarez-Dolado;Ricardo Pardal;Jose M. Garcia-Verdugo;John R. Fike

  • Applying the principles of stem-cell biology to cancer

    Ricardo Pardal;Michael F. Clarke;Sean J. Morrison

  • Endothelial and perivascular cells maintain haematopoietic stem cells

    Lei Ding;Thomas L. Saunders;Grigori Enikolopov;Sean J. Morrison

  • Asymmetric and symmetric stem-cell divisions in development and cancer

    Sean J. Morrison;Judith Kimble

  • The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

    Sean J. Morrison;Irving L. Weissman

  • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

    Ömer H. Yilmaz;Riccardo Valdez;Brian K. Theisen;Wei Guo

  • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

    Anna V. Molofsky;Ricardo Pardal;Toshihide Iwashita;In Kyung Park

  • Regulatory Mechanisms in Stem Cell Biology

    Sean J Morrison;Nirao M Shah;David J Anderson

  • Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

    Lei Ding;Sean J. Morrison

  • Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

    Mark Shackleton;Elsa Quintana;Eric R. Fearon;Sean J. Morrison

  • Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty

    Jeffrey A. Magee;Elena Piskounova;Sean J. Morrison

  • Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow

    Bo O. Zhou;Rui Yue;Malea Malea M Murphy;James G. Peyer

Frequent Co-Authors

Irving L. Weissman
Irving L. Weissman Stanford University
David J. Anderson
David J. Anderson California Institute of Technology
Michael F. Clarke
Michael F. Clarke Stanford University
Ralph J. DeBerardinis
Ralph J. DeBerardinis The University of Texas Southwestern Medical Center
Max S. Wicha
Max S. Wicha University of Michigan–Ann Arbor
Timothy M. Johnson
Timothy M. Johnson University of Michigan–Ann Arbor
Thomas L. Saunders
Thomas L. Saunders University of Michigan–Ann Arbor
Barbara J. Wold
Barbara J. Wold California Institute of Technology

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