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Biology and Biochemistry

D-Index
65
Citations
21673
World Ranking
8986
National Ranking
3992

Overview

Thomas L. Saunders is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans several interconnected fields, primarily within biochemistry, genetics, and molecular biology, along with medicine. The main areas of focus reflect an integration of molecular biology, epidemiology, cell biology, genetics, and cellular and molecular neuroscience.

Their research topics cover a broad spectrum including CRISPR and genetic engineering, receptor mechanisms and signaling, pluripotent stem cells research, bone and dental protein studies, cellular transport and secretion, animal genetics and reproduction, and dental development and anomalies.

Among their recent papers are:

  • "Principles of Genetic Engineering," 2020, Genes
  • "Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis," 2023, Nature Communications
  • "Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation," 2020, Cell Stem Cell
  • "Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice," 2022, Journal of Clinical Investigation
  • "Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice," 2020, Aging Pathobiology and Therapeutics

Frequent co-authors collaborating with Saunders include:

  • Elizabeth Hughes
  • Elizabeth D. Hughes
  • Philip D. King
  • Eroboghene E. Ubogu
  • Jeremy A. Conner

Publications by Saunders appear commonly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • PLoS ONE
  • Aging Pathobiology and Therapeutics
  • JCI Insight

Thomas L. Saunders's body of work demonstrates engagement with cutting-edge topics in genetics and molecular biology, emphasizing both fundamental science and applications in cellular mechanisms and disease models. Their diverse publication record and collaborations indicate a multidisciplinary approach to research within the life sciences.

Best Publications

  • Endothelial and perivascular cells maintain haematopoietic stem cells

    Lei Ding;Thomas L. Saunders;Grigori Enikolopov;Sean J. Morrison

  • Receptor editing: an approach by autoreactive B cells to escape tolerance.

    Thomas Saunders;Sally Camper;Martin Weigert

  • Nrl is required for rod photoreceptor development

    Alan J. Mears;Mineo Kondo;Mineo Kondo;Prabodha K. Swain;Yuichiro Takada

  • Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

    Kezhong Zhang;Xiaohua Shen;Jun Wu;Kenjiro Sakaki

  • The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

    Petr Malý;Aron D Thall;Bronislawa Petryniak;Clare E Rogers

  • Podocyte Depletion Causes Glomerulosclerosis: Diphtheria Toxin–Induced Podocyte Depletion in Rats Expressing Human Diphtheria Toxin Receptor Transgene

    Bryan L. Wharram;Meera Goyal;Jocelyn E. Wiggins;Silja K. Sanden

  • ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress

    Jun Wu;D. Thomas Rutkowski;Meghan Dubois;Jayanth Swathirajan

  • Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

    Daisuke Nakada;Thomas L. Saunders;Sean J. Morrison

  • Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene

    Frank J. Probst;Robert A. Fridell;Yehoash Raphael;Thomas L. Saunders

  • Sox17 Dependence Distinguishes the Transcriptional Regulation of Fetal from Adult Hematopoietic Stem Cells

    Injune Kim;Thomas L. Saunders;Sean J. Morrison

  • Role of Ahch in gonadal development and gametogenesis

    R N Yu;M Ito;T L Saunders;S A Camper

  • Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

    Julie M. Jones;Pinaki Datta;Srinivasa M. Srinivasula;Weizhen Ji

  • Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

    Tamar Ben-Yosef;Inna A. Belyantseva;Thomas L. Saunders;Elizabeth D. Hughes

  • Resting zone of the growth plate houses a unique class of skeletal stem cells

    Koji Mizuhashi;Wanida Ono;Yuki Matsushita;Naoko Sakagami

  • Ribosomal protein L24 defect in Belly spot and tail (Bst), a mouse Minute

    Edward R. Oliver;Thomas L. Saunders;Susan A. Tarlé;Thomas M Glaser

  • Mice Lacking Sodium Channel β1 Subunits Display Defects in Neuronal Excitability, Sodium Channel Expression, and Nodal Architecture

    Chunling Chen;Ruth E. Westenbroek;Xiaorong Xu;Chris A. Edwards

  • Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V.

    Cui J;O'Shea Ks;Purkayastha A;Saunders Tl

  • Targeted disruption of the pituitary glycoprotein hormone alpha-subunit produces hypogonadal and hypothyroid mice.

    Susan K. Kendall;Linda C. Samuelson;Thomas L. Saunders;Ruth I. Wood

  • RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis

    Lin Yu Lu;Jiaxue Wu;Lin Ye;Galina B. Gavrilina

  • MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

    Yi Tang;R. Grant Rowe;Elliot L. Botvinick;Abhishek Kurup

Frequent Co-Authors

Sally A. Camper
Sally A. Camper University of Michigan–Ann Arbor
David Ginsburg
David Ginsburg University of Michigan–Ann Arbor
Linda C. Samuelson
Linda C. Samuelson University of Michigan–Ann Arbor
Sean J. Morrison
Sean J. Morrison The University of Texas Southwestern Medical Center
Stephen J. Weiss
Stephen J. Weiss University of Michigan–Ann Arbor
Pavan Reddy
Pavan Reddy Baylor College of Medicine
David F. Dolan
David F. Dolan University of Michigan–Ann Arbor
Joshua D. Berke
Joshua D. Berke University of California, San Francisco
Robert J. Morell
Robert J. Morell National Institutes of Health
Thomas B. Friedman
Thomas B. Friedman National Institutes of Health

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