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Immunology

D-Index
84
Citations
25213
World Ranking
1378
National Ranking
707

Overview

David Nemazee is affiliated with the Scripps Research Institute in the United States. Their research spans several interconnected fields, primarily focusing on Medicine, Immunology, and Microbiology. Within these broader areas, their work covers specific subfields such as Infectious Diseases, Immunology, Animal Science and Zoology, Molecular Biology, and Virology.

The main topics of Nemazee's research include:

  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • COVID-19 Clinical Research Studies
  • HIV Research and Treatment

Nemazee has contributed to numerous publications in prominent scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Science
  • Science Translational Medicine
  • Cell Host & Microbe

Among recent research papers authored or co-authored by Nemazee are the following:

  • Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model, 2020, Science
  • Broad neutralization of SARS-related viruses by human monoclonal antibodies, 2020, Science
  • Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants, 2021, Science
  • Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody, 2021, Science
  • Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate, 2020, Science

Nemazee frequently collaborates with several co-authors, including:

  • Deli Huang
  • Linghang Peng
  • Dennis R. Burton
  • Meng Yuan
  • Ian A. Wilson

Best Publications

  • Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.

    Thomas F. Rogers;Thomas F. Rogers;Fangzhu Zhao;Deli Huang;Nathan Beutler

  • Receptor editing in self-reactive bone marrow B cells

    Susan L. Tiegs;David M. Russell;David Nemazee

  • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

    David A. Nemazee;Kurt Bürki

  • Rational HIV immunogen design to target specific germline B cell receptors

    Joseph Jardine;Jean Philippe Julien;Jean Philippe Julien;Sergey Menis;Takayuki Ota

  • Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling

    Amanda L. Gavin;Kasper Hoebe;Bao Duong;Takayuki Ota

  • Broad neutralization of SARS-related viruses by human monoclonal antibodies.

    Anna Z. Wec;Daniel Wrapp;Andrew S. Herbert;Daniel P. Maurer

  • Mechanisms of central tolerance for B cells

    David Nemazee

  • Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.

    Eugenia Spanopoulou;Christopher A. J. Roman;Lynn M. Corcoran;Mark S. Schlissel

  • Receptor editing in lymphocyte development and central tolerance

    David Nemazee

  • The immune epitope database and analysis resource: from vision to blueprint.

    Bjoern Peters;John Sidney;Phil Bourne;Huynh-Hoa Bui

  • Peripheral deletion of self-reactive B cells

    David M. Russell;Zlatko Dembić;Grant Morahan;J. F. A. P. Miller

  • Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

    Joseph G. Jardine;Takayuki Ota;Devin Sok;Devin Sok;Matthias Pauthner;Matthias Pauthner

  • Contribution of receptor editing to the antibody repertoire.

    Rafael Casellas;Tien-An Yang Shih;Markus Kleinewietfeld;Jasna Rakonjac

  • Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.

    Meng Yuan;Deli Huang;Chang Chun D. Lee;Nicholas C. Wu

  • Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate.

    Sandhya Bangaru;Gabriel Ozorowski;Hannah L Turner;Aleksandar Antanasijevic

  • Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

    Robert K. Abbott;Jeong Hyun Lee;Jeong Hyun Lee;Sergey Menis;Patrick Skog

  • Receptor Editing in a Transgenic Mouse Model: Site, Efficiency, and Role in B Cell Tolerance and Antibody Diversification

    Roberta Pelanda;Stephan Schwers;Eiichiro Sonoda;Raul M Torres

  • V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

    Fotini Papavasiliou;Rafael Casellas;Heikyung Suh;Xiao-Feng Qin

  • Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras.

    David Nemazee;Kurt Buerki

  • Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.

    C. Garrett Rappazzo;Longping V. Tse;Chengzi I. Kaku;Daniel Wrapp

  • Revising B Cell Receptors

    David Nemazee;Martin Weigert

  • Receptor Selection in B and T Lymphocytes

    David Nemazee

Frequent Co-Authors

Devin Sok
Devin Sok Scripps Research Institute
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
William R. Schief
William R. Schief Scripps Research Institute
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Valerie Kouskoff
Valerie Kouskoff University of Manchester
Leonidas Stamatatos
Leonidas Stamatatos Fred Hutchinson Cancer Research Center
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
David W. Russell
David W. Russell University of Washington
Ann J. Feeney
Ann J. Feeney Scripps Research Institute

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