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Immunology

D-Index
56
Citations
15109
World Ranking
3685
National Ranking
1698

Overview

Devin Sok is a researcher affiliated with the Scripps Research Institute in the United States. Their work spans several interconnected fields within biomedical science, focusing on infectious diseases, immunology, molecular biology, and virology. Sok's research agenda includes multiple aspects of viral pathogens, immune responses, and vaccine development.

Their publication record includes contributions to key topics such as:

  • HIV Research and Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • Viral Gastroenteritis Research and Epidemiology
  • Vaccines and Immunoinformatics Approaches
  • T-cell and B-cell Immunology

Significant recent papers by Devin Sok include:

  • Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model, 2020, Science
  • Structural basis of a shared antibody response to SARS-CoV-2, 2020, Science
  • Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines, 2020, Cell Reports
  • Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates, 2020, PLoS Pathogens
  • Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Sok frequently collaborates with other researchers in these areas. Their frequent co-authors include:

  • Dennis R. Burton
  • Andrew B. Ward
  • Elise Landais
  • Gabriel Ozorowski
  • Fangzhu Zhao

Regarding publication venues, Devin Sok's works have appeared multiple times in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • Science
  • Cell Reports
  • Science Translational Medicine

Their main fields of study are Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with dedicated research in subfields such as Infectious Diseases, Virology, Immunology, Molecular Biology, and Radiology, Nuclear Medicine, and Imaging.

Best Publications

  • Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.

    Thomas F. Rogers;Thomas F. Rogers;Fangzhu Zhao;Deli Huang;Nathan Beutler

  • Crystal structure of a soluble cleaved HIV-1 envelope trimer.

    Jean-Philippe Julien;Jean-Philippe Julien;Albert Cupo;Devin Sok;Devin Sok;Robyn L. Stanfield;Robyn L. Stanfield

  • Rational HIV immunogen design to target specific germline B cell receptors

    Joseph Jardine;Jean Philippe Julien;Jean Philippe Julien;Sergey Menis;Takayuki Ota

  • Structural basis of a shared antibody response to SARS-CoV-2.

    Meng Yuan;Hejun Liu;Nicholas C. Wu;Chang Chun D. Lee

  • HIV-1 neutralizing antibodies induced by native-like envelope trimers

    Rogier W. Sanders;Rogier W. Sanders;Marit J. Van Gils;Ronald Derking;Devin Sok;Devin Sok

  • HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.

    Joseph G. Jardine;Daniel W. Kulp;Colin Havenar-Daughton;Anita Sarkar

  • Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

    Joseph G. Jardine;Takayuki Ota;Devin Sok;Devin Sok;Matthias Pauthner;Matthias Pauthner

  • Recent progress in broadly neutralizing antibodies to HIV

    Devin Sok;Dennis R Burton

  • Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.

    Devin Sok;Marit J. van Gils;Matthias Pauthner;Jean-Philippe Julien

  • Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.

    Jean-Philippe Julien;Devin Sok;Reza Khayat;Jeong Hyun Lee

  • Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers

    Dena Marrinucci;Dena Marrinucci;Kelly Bethel;Anand Kolatkar;Madelyn S Luttgen

  • Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

    Amelia Escolano;Jon M. Steichen;Pia Dosenovic;Daniel W. Kulp

  • Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.

    Matthias Pauthner;Colin Havenar-Daughton;Colin Havenar-Daughton;Devin Sok;Joseph P. Nkolola;Joseph P. Nkolola

  • Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

    Bryan Briney;Devin Sok;Joseph G. Jardine;Daniel W. Kulp

  • A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

    Jon M. Steichen;Ying-Cing Lin;Colin Havenar-Daughton;Colin Havenar-Daughton;Simone Pecetta

  • A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

    Jeong Hyun Lee;Jeong Hyun Lee;Raiees Andrabi;Raiees Andrabi;Ching Yao Su;Anila Yasmeen

  • Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.

    Laura E. McCoy;Laura E. McCoy;Marit J. van Gils;Gabriel Ozorowski;Terrence Messmer

  • Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak

    Zachary A. Bornholdt;Hannah L. Turner;Charles D. Murin;Wen Li

  • Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies

    Fernando Garces;Devin Sok;Leopold Kong;Leopold Kong;Ryan McBride

  • The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

    Devin Sok;Uri Laserson;Uri Laserson;Jonathan Laserson;Yi-Ping Liu

Frequent Co-Authors

Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
William R. Schief
William R. Schief Scripps Research Institute
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Pascal Poignard
Pascal Poignard Grenoble Alpes University
Jean-Philippe Julien
Jean-Philippe Julien University of Toronto
Shane Crotty
Shane Crotty La Jolla Institute For Allergy & Immunology
David Nemazee
David Nemazee Scripps Research Institute
Guido Silvestri
Guido Silvestri Emory University

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