World's Best Scientists 2026 revealed!

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Immunology

D-Index
60
Citations
22811
World Ranking
3286
National Ranking
150

Overview

Pascal Poignard is affiliated with Grenoble Alpes University in France and has contributed primarily to the field of Medicine, with a focus on Infectious Diseases. Their research spans multiple subfields including Immunology, Virology, Molecular Biology, and Neurology.

The scientist's work extensively covers topics related to SARS-CoV-2 and COVID-19, including clinical research studies, detection and testing methods, and long-term effects of COVID-19. Additional research interests include HIV treatment and malaria control, as well as the role of the complement system in diseases.

Pascal Poignard has published in several scientific venues, frequently contributing to bioRxiv (Cold Spring Harbor Laboratory) with seven publications. Other notable journals where their work appears include Frontiers in Immunology, Scientific Reports, Journal of Infection, and eLife.

Recent publications include the following:

  • Complement Alternative and Mannose-Binding Lectin Pathway Activation Is Associated With COVID-19 Mortality, 2021, Frontiers in Immunology
  • Elicitation of potent SARS-CoV-2 neutralizing antibody responses through immunization with a versatile adenovirus-inspired multimerization platform, 2022, Molecular Therapy
  • SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody Monotherapy, 2021, Emerging Infectious Diseases
  • Clinical and laboratory characteristics of symptomatic healthcare workers with suspected COVID-19: a prospective cohort study, 2021, Scientific Reports
  • AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome, 2022, International Journal of Molecular Sciences

Frequent co-authors in Pascal Poignard's collaborative research efforts include Isabelle Bally, Axelle Amen, Marlyse Buisson, Olivier Épaulard, and Alexandre Gaymard.

The scientist's body of work reflects a focus on viral infectious diseases, immune responses, and molecular mechanisms underlying severe viral infections, particularly COVID-19. Their contributions have appeared in a diverse range of journals and research platforms pertinent to immunology and infectious disease communities.

Best Publications

  • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.

    Laura M. Walker;Sanjay K. Phogat;Po-Ying Chan-Hui;Denise Wagner

  • Broad neutralization coverage of HIV by multiple highly potent antibodies

    Laura M. Walker;Michael Huber;Michael Huber;Katie J. Doores;Katie J. Doores;Emilia Falkowska;Emilia Falkowska

  • Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.

    Johannes F. Scheid;Hugo Mouquet;Beatrix Ueberheide;Ron Diskin

  • Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

    Michela Locci;Michela Locci;Colin Havenar-Daughton;Colin Havenar-Daughton;Elise Landais;Jennifer Wu

  • A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

    Robert Pejchal;Katie J. Doores;Katie J. Doores;Laura M. Walker;Reza Khayat

  • Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm

    Melissa D. Simek;Wasima Rida;Frances H. Priddy;Pham Pung

  • Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

    Dan H. Barouch;James B. Whitney;Brian Moldt;Florian Klein

  • Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques.

    Ann J Hessell;Pascal Poignard;Meredith Hunter;Lars Hangartner

  • Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

    Ann J. Hessell;Eva G. Rakasz;Pascal Poignard;Pascal Poignard;Lars Hangartner;Lars Hangartner

  • Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

    Dennis R. Burton;Dennis R. Burton;Pascal Poignard;Robyn L. Stanfield;Ian A. Wilson

  • Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

    Brian Moldt;Eva G. Rakasz;Niccole Schultz;Po-Ying Chan-Hui

  • Broadly neutralizing antibody responses in a large longitudinal sub-Saharan HIV primary infection cohort

    Elise Landais;Xiayu Huang;Colin Havenar-Daughton;Ben Murrell

  • A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals.

    Laura M. Walker;Melissa D. Simek;Frances Priddy;Johannes S. Gach

  • Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

    Ann J. Hessell;Eva G. Rakasz;David M. Tehrani;Michael Huber

  • Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

    Emilia Falkowska;Khoa M. Le;Khoa M. Le;Alejandra Ramos;Alejandra Ramos;Katie J. Doores;Katie J. Doores;Katie J. Doores

  • Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1

    Aran F. Labrijn;Pascal Poignard;Aarti Raja;Michael B. Zwick

  • Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding.

    Q J Sattentau;J P Moore;F Vignaux;F Traincard

  • Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.

    Jean-Philippe Julien;Devin Sok;Reza Khayat;Jeong Hyun Lee

  • Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.

    Claudia Blattner;Jeong Hyun Lee;Kwinten Sliepen;Ronald Derking

  • GP120: Biologic Aspects of Structural Features

    Pascal Poignard;Erica Ollmann Saphire;Paul Whi Parren;Dennis R. Burton

  • IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform.

    N. Lance Hepler;Konrad Scheffler;Steven Weaver;Ben Murrell

Frequent Co-Authors

Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Wayne C. Koff
Wayne C. Koff International AIDS Vaccine Initiative
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Devin Sok
Devin Sok Scripps Research Institute
Michael S. Seaman
Michael S. Seaman Beth Israel Deaconess Medical Center
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Katie J. Doores
Katie J. Doores King's College London
Bruce D. Walker
Bruce D. Walker Harvard University
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam

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