D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 49 Citations 14,724 90 World Ranking 2864 National Ranking 1358

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Virus
  • Antibody

His primary scientific interests are in Virology, Antibody, Neutralization, Epitope and Immunology. His Virology research is multidisciplinary, incorporating perspectives in HIV vaccine and Monoclonal antibody. His work on Humoral immunity as part of general Antibody study is frequently connected to Trimer, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

His Neutralization study incorporates themes from Recombinant DNA, Complementarity determining region, Primary and secondary antibodies, Antigen and Molecular biology. His research integrates issues of Protein structure and Glycan in his study of Epitope. His Immunology research includes elements of AIDS Vaccines and Acquired immunodeficiency syndrome.

His most cited work include:

  • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. (1493 citations)
  • Broad neutralization coverage of HIV by multiple highly potent antibodies (1191 citations)
  • HIV vaccine design and the neutralizing antibody problem (760 citations)

What are the main themes of his work throughout his whole career to date?

Wayne C. Koff mostly deals with Virology, Immunology, Antibody, Acquired immunodeficiency syndrome and Immune system. His work carried out in the field of Virology brings together such families of science as HIV vaccine, Monoclonal antibody and Antigen. His biological study spans a wide range of topics, including Immunogen and Microbiology.

His study in Antibody concentrates on Epitope and Neutralization. Wayne C. Koff interconnects Protein structure and Antigenicity in the investigation of issues within Neutralization. His studies deal with areas such as Cytotoxic T cell and Recombinant DNA as well as Virus.

He most often published in these fields:

  • Virology (52.67%)
  • Immunology (35.33%)
  • Antibody (30.67%)

What were the highlights of his more recent work (between 2011-2021)?

  • Virology (52.67%)
  • Antibody (30.67%)
  • Immune system (18.00%)

In recent papers he was focusing on the following fields of study:

Wayne C. Koff mainly investigates Virology, Antibody, Immune system, Epitope and Immunology. His Virology study combines topics in areas such as HIV vaccine, Immunogen and Antigen. His Antibody study focuses on Neutralization in particular.

The various areas that Wayne C. Koff examines in his Immune system study include Computational biology and Vaccination. His study looks at the relationship between Epitope and fields such as Monoclonal antibody, as well as how they intersect with chemical problems. His studies in Immunology integrate themes in fields like AIDS Vaccines, Acquired immunodeficiency syndrome and Gene.

Between 2011 and 2021, his most popular works were:

  • HIV-1 neutralizing antibodies induced by native-like envelope trimers (375 citations)
  • Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions (304 citations)
  • Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers (288 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Virus
  • Immune system

Antibody, Virology, Epitope, Neutralization and Glycan are his primary areas of study. His work deals with themes such as AIDS Vaccines and Glycoprotein, which intersect with Antibody. In his research, Immune system, Recombinant DNA and Virus is intimately related to Antigen, which falls under the overarching field of Virology.

His research in Neutralization tackles topics such as Primary and secondary antibodies which are related to areas like Specific antibody, Lineage, Paratope, Molecular biology and Complementarity determining region. Wayne C. Koff has researched Glycan in several fields, including Glycosylation, Gp41 and Monoclonal antibody. His Immunology research includes themes of Acquired immunodeficiency syndrome and Intensive care medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.

Laura M. Walker;Sanjay K. Phogat;Po-Ying Chan-Hui;Denise Wagner.
Science (2009)

2279 Citations

Broad neutralization coverage of HIV by multiple highly potent antibodies

Laura M. Walker;Michael Huber;Michael Huber;Katie J. Doores;Katie J. Doores;Emilia Falkowska;Emilia Falkowska.
Nature (2011)

1374 Citations

HIV vaccine design and the neutralizing antibody problem

Dennis R Burton;Ronald C Desrosiers;Robert W Doms;Wayne C Koff.
Nature Immunology (2004)

1014 Citations

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman.
Nature (2011)

846 Citations

Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm

Melissa D. Simek;Wasima Rida;Frances H. Priddy;Pham Pung.
Journal of Virology (2009)

698 Citations

Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

Ann J. Hessell;Eva G. Rakasz;Pascal Poignard;Pascal Poignard;Lars Hangartner;Lars Hangartner.
PLOS Pathogens (2009)

572 Citations

Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

Ann J. Hessell;Eva G. Rakasz;David M. Tehrani;Michael Huber.
Journal of Virology (2010)

437 Citations

HIV-1 neutralizing antibodies induced by native-like envelope trimers

Rogier W. Sanders;Rogier W. Sanders;Marit J. Van Gils;Ronald Derking;Devin Sok;Devin Sok.
Science (2015)

413 Citations

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

James B. Munro;Jason Gorman;Xiaochu Ma;Zhou Zhou.
Science (2014)

385 Citations

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

Emilia Falkowska;Khoa M. Le;Khoa M. Le;Alejandra Ramos;Alejandra Ramos;Katie J. Doores;Katie J. Doores;Katie J. Doores.
Immunity (2014)

362 Citations

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