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Immunology

D-Index
62
Citations
20412
World Ranking
3098
National Ranking
1451

Overview

Wayne C. Koff is affiliated with the International AIDS Vaccine Initiative in the United States. Their primary research contributions are situated within the field of Medicine, with a focus on Infectious Diseases, Epidemiology, Molecular Biology, Immunology, and Health.

The scientist's work addresses several main topics, including:

  • SARS-CoV-2 and COVID-19 Research
  • Vaccines and immunoinformatics approaches
  • Influenza Virus Research Studies
  • Vaccine Coverage and Hesitancy
  • Immune responses and vaccinations
  • Immunotherapy and Immune Responses
  • Hepatitis B Virus Studies

Recent publications by Wayne C. Koff include:

  • "Covid-19 and Immunity in Aging Populations - A New Research Agenda," 2020, New England Journal of Medicine
  • "Development and deployment of COVID-19 vaccines for those most vulnerable," 2021, Science Translational Medicine
  • "A universal coronavirus vaccine," 2021, Science

Frequent co-authors in Koff's research collaborations include:

  • Manish Sadarangani
  • Tobias R. Kollmann
  • Casey P. Shannon
  • Rym Ben-Othman
  • Nicole Gladish

Koff's research has been published most frequently in the following venues:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Frontiers in Immunology
  • Vaccine
  • New England Journal of Medicine
  • Trends in Immunology

Best Publications

  • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.

    Laura M. Walker;Sanjay K. Phogat;Po-Ying Chan-Hui;Denise Wagner

  • Broad neutralization coverage of HIV by multiple highly potent antibodies

    Laura M. Walker;Michael Huber;Michael Huber;Katie J. Doores;Katie J. Doores;Emilia Falkowska;Emilia Falkowska

  • HIV vaccine design and the neutralizing antibody problem

    Dennis R Burton;Ronald C Desrosiers;Robert W Doms;Wayne C Koff

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  • Focused evolution of hiv-1 neutralizing antibodies revealed by crystal structures and deep sequencing

    John R. Mascola;Gary Nabel;Barton F. Haynes;Xueling Wu

  • Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm

    Melissa D. Simek;Wasima Rida;Frances H. Priddy;Pham Pung

  • Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

    Ann J. Hessell;Eva G. Rakasz;Pascal Poignard;Pascal Poignard;Lars Hangartner;Lars Hangartner

  • Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

    James B. Munro;Jason Gorman;Xiaochu Ma;Zhou Zhou

  • HIV-1 neutralizing antibodies induced by native-like envelope trimers

    Rogier W. Sanders;Rogier W. Sanders;Marit J. Van Gils;Ronald Derking;Devin Sok;Devin Sok

  • Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

    Ann J. Hessell;Eva G. Rakasz;David M. Tehrani;Michael Huber

  • Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

    Emilia Falkowska;Khoa M. Le;Khoa M. Le;Alejandra Ramos;Alejandra Ramos;Katie J. Doores;Katie J. Doores;Katie J. Doores

  • Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G

    Guillaume B.E. Stewart-Jones;Cinque Soto;Thomas Lemmin;Thomas Lemmin;Gwo Yu Chuang

  • Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.

    Tongqing Zhou;Jiang Zhu;Xueling Wu;Stephanie Moquin

  • Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

    Rui Kong;Kai Xu;Tongqing Zhou;Priyamvada Acharya

  • Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

    Steven W. de Taeye;Gabriel Ozorowski;Alba Torrents de la Peña;Miklos Guttman

  • Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

    Marie Pancera;Syed Shahzad-Ul-Hussan;Nicole A. Doria-Rose;Jason S. McLellan

  • Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors

    Tongqing Zhou;Rebecca M. Lynch;Lei Chen;Priyamvada Acharya

  • Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans.

    David I Watkins;Dennis R Burton;Esper G Kallas;John P Moore

  • Accelerating Next Generation Vaccine Development for Global Disease Prevention

    Wayne C Koff;Dennis R. Burton;Dennis R. Burton;Philip R.Johnson;Bruce D. Walker;Bruce D. Walker;Bruce D. Walker

  • HIV vaccine design: insights from live attenuated SIV vaccines

    Wayne C Koff;Philip R Johnson;David I Watkins;Dennis R Burton

Frequent Co-Authors

Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Pascal Poignard
Pascal Poignard Grenoble Alpes University
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
John R. Mascola
John R. Mascola ModeX Therapeutics
Marie Pancera
Marie Pancera Fred Hutchinson Cancer Research Center
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Yongping Yang
Yongping Yang National Institutes of Health
David I. Watkins
David I. Watkins George Washington University
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam

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