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Chemistry

D-Index
63
Citations
20565
World Ranking
8275
National Ranking
2394

Overview

Nico Tjandra is affiliated with the National Institutes of Health in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions to medicine. They have published extensively in subfields including molecular biology, cell biology, physiology, virology, and rheumatology.

Their main topics of research cover cellular transport and secretion, ubiquitin and proteasome pathways, HIV research and treatment, GDF15 and related biomarkers, microtubule and mitosis dynamics, protein structure and dynamics, and enzyme structure and function.

Frequent collaborators in their work include:

  • David A. Nyenhuis
  • Susan M. Watanabe
  • Madeleine Strickland
  • Daniel L. Morris
  • James M. Gruschus

Tjandra has published multiple papers across various scientific journals. Notably, some recent papers include:

  • Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes, 2020, Nature Structural & Molecular Biology
  • Selective Targeting of Virus Replication by Proton Pump Inhibitors, 2020, Scientific Reports
  • Nix interacts with WIPI2 to induce mitophagy, 2023, The EMBO Journal
  • The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold, 2021, Nature Chemical Biology
  • Humanin selectively prevents the activation of pro-apoptotic protein BID by sequestering it into fibers, 2020, Journal of Biological Chemistry

They have contributed multiple times to key publication venues which include:

  • Biophysical Journal
  • Biochemistry
  • Journal of Biological Chemistry
  • Viruses
  • Nature Structural & Molecular Biology

Best Publications

  • The Xplor-NIH NMR molecular structure determination package.

    Charles D Schwieters;John J Kuszewski;Nico Tjandra;G Marius Clore

  • Direct Measurement of Distances and Angles in Biomolecules by NMR in a Dilute Liquid Crystalline Medium

    Nico Tjandra;Ad Bax

  • Solution structure of calcium-free calmodulin.

    Hitoshi Kuboniwa;Nico Tjandra;Stephan Grzesiek;Hao Ren

  • Rotational Diffusion Anisotropy of Human Ubiquitin from 15N NMR Relaxation

    Nico Tjandra;Scott E. Feller;Richard W. Pastor;Ad Bax

  • Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution

    N Tjandra;J G Omichinski;A M Gronenborn;G M Clore

  • Dipolar couplings in macromolecular structure determination.

    Ad Bax;Georg Kontaxis;Nico Tjandra

  • Direct Structure Refinement against Residual Dipolar Couplings in the Presence of Rhombicity of Unknown Magnitude

    G.Marius Clore;Angela M. Gronenborn;Nico Tjandra

  • Protein Backbone Dynamics and 15N Chemical Shift Anisotropy from Quantitative Measurement of Relaxation Interference Effects

    Nico Tjandra;and Attila Szabo;Ad Bax

  • Magnetic Field Dependence of Nitrogen−Proton J Splittings in 15N-Enriched Human Ubiquitin Resulting from Relaxation Interference and Residual Dipolar Coupling

    Nico Tjandra;and Stephan Grzesiek;Ad Bax

  • Rotational dynamics of calcium-free calmodulin studied by 15N-NMR relaxation measurements

    Nico Tjandra;Hitoshi Kuboniwa;Hao Ren;Ad Bax

  • High-resolution heteronuclear NMR of human ubiquitin in an aqueous liquid crystalline medium.

    Ad Bax;Nico Tjandra

  • Anisotropic rotational diffusion of perdeuterated HIV protease from 15N NMR relaxation measurements at two magnetic fields

    Nico Tjandra;Paul Wingfield;Stephen Stahl;Ad Bax

  • Residual dipolar couplings in NMR structure analysis.

    Rebecca S Lipsitz;Nico Tjandra

  • The NMR Structure of a DNA Dodecamer in an Aqueous Dilute Liquid Crystalline Phase

    Nico Tjandra;Shin-ichi Tate;Akira Ono;Masatsune Kainosho

  • Structural basis for redox regulation of Yap1 transcription factor localization

    Matthew J. Wood;Gisela Storz;Nico Tjandra

  • Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.

    N. Tjandra;D.S. Garrett;A.M. Gronenborn;A. Bax

  • Direct Measurement of 15N Chemical Shift Anisotropy in Solution

    David Fushman;Nico Tjandra;David Cowburn

  • The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle.

    Motoshi Suzuki;Seon Yong Jeong;Mariusz Karbowski;Richard J Youle

  • Refined solution structure and backbone dynamics of HIV-1 Nef

    S. Grzesiek;A. Bax;J. S. Hu;J. Kaufman

  • NMR dipolar couplings for the structure determination of biopolymers in solution

    Eva de Alba;Nico Tjandra

Frequent Co-Authors

Ad Bax
Ad Bax National Institutes of Health
Richard J. Youle
Richard J. Youle National Institutes of Health
G. Marius Clore
G. Marius Clore National Institutes of Health
Stephan Grzesiek
Stephan Grzesiek University of Basel
Rodolfo Ghirlando
Rodolfo Ghirlando National Institutes of Health
Alan Peterkofsky
Alan Peterkofsky National Institutes of Health
Angela M. Gronenborn
Angela M. Gronenborn University of Pittsburgh
Loren D. Walensky
Loren D. Walensky Harvard University
Leonid Medved
Leonid Medved University of Maryland, Baltimore
Michael F. Summers
Michael F. Summers University of Maryland, Baltimore County

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