2026 Loren D. Walensky: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	67	8096	7471	3666	3294	206	20188

Research.com Recognitions

2015 - E. Mead Johnson Award, Society for Pediatric Research
Member of the Association of American Physicians
Member of the Association of American Physicians
Member of the Association of American Physicians

Overview

Loren D. Walensky is affiliated with Harvard University in the United States and contributes to research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Oncology, Immunology, Public Health, Environmental and Occupational Health, and Surgery.

The scientist's research focuses on key topics such as RNA Interference and Gene Delivery, Cell death mechanisms and regulation, Peptidase Inhibition and Analysis, Pancreatic function and diabetes, Diabetes and associated disorders, Advanced biosensing and bioanalysis techniques, and Health and Medical Research Impacts.

Among the recent papers authored or co-authored by Loren D. Walensky are:

Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival (2020, The Journal of Cell Biology)
Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma (2023, Nature Medicine)
Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation (2020, Nature Metabolism)
Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets (2021, Cell Reports)
Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization (2020, Molecular Cell)

Frequent publication venues for this researcher include:

Cell Reports
Nature Communications
JAMA
Cell chemical biology
Nature Chemical Biology

Regular collaborators in their research are Gregory H. Bird, Thomas E. Wales, John R. Engen, Hyuk-Soo Seo, and Sirano Dhe-Paganon.

Loren D. Walensky has received the E. Mead Johnson Award from the Society for Pediatric Research in 2015 and holds membership in the Association of American Physicians.

Best Publications

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

Anthony Letai;Michael C. Bassik;Loren D. Walensky;Mia D. Sorcinelli

2098
Citations
Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix

Loren D. Walensky;Andrew L. Kung;Andrew L. Kung;Iris Escher;Thomas J. Malia;Thomas J. Malia

1708
Citations
Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

Loren D. Walensky;Gregory H. Bird

922
Citations
BAX activation is initiated at a novel interaction site

Evripidis Gavathiotis;Motoshi Suzuki;Marguerite L. Davis;Marguerite L. Davis;Kenneth L. Pitter;Kenneth L. Pitter

823
Citations
Reactivation of the p53 Tumor Suppressor Pathway by a Stapled p53 Peptide

Federico Bernal;Andrew F. Tyler;Stanley J. Korsmeyer;Loren D. Walensky

665
Citations
A Stapled BID BH3 Helix Directly Binds and Activates BAX

Loren D. Walensky;Kenneth Pitter;Joel Morash;Kyoung Joon Oh

493
Citations
The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.

Michelle L Stewart;Emiko Fire;Amy E Keating;Loren D Walensky

471
Citations
The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members.

Gregory L Verdine;Loren D Walensky

455
Citations
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

Jennifer A. Perry;Adam Kiezun;Peter Tonzi;Eliezer M. Van Allen;Eliezer M. Van Allen

440
Citations
Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux.

Andrew M. Cameron;Joseph P. Steiner;David M. Sabatini;Adam I. Kaplin

426
Citations
Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association.

Lei Shen;Feng Liang;Loren D. Walensky;Richard L. Huganir

420
Citations
Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

Gregory H. Bird;Navid Madani;Alisa F. Perry;Amy M. Princiotto

374
Citations
Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Nika N Danial;Loren D Walensky;Chen-Yu Zhang;Cheol Soo Choi

367
Citations
Targeted Disruption of the EZH2/EED Complex Inhibits EZH2-dependent Cancer

Woojin Kim;Gregory H Bird;Tobias Neff;Guoji Guo;Guoji Guo

352
Citations
A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53

Federico Bernal;Mark Wade;Marina Godes;Tina N. Davis

348
Citations
BCL-2 in the crosshairs: tipping the balance of life and death.

L D Walensky;L D Walensky

344
Citations
BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX

Evripidis Gavathiotis;Denis E. Reyna;Denis E. Reyna;Marguerite L. Davis;Marguerite L. Davis;Gregory H. Bird;Gregory H. Bird

337
Citations
Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosomes of mammalian sperm.

Loren D. Walensky;Solomon H. Snyder

333
Citations
Targeted Disruption of the BCL9/β-Catenin Complex Inhibits Oncogenic Wnt Signaling

Kohichi Takada;Di Zhu;Gregory H. Bird;Kumar Sukhdeo

273
Citations
Abstract A41: Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

Adam Kiezun;Jennifer Perry;Peter Tonzi;Eliezer Van Allen

3
Citations