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Biology and Biochemistry

D-Index
55
Citations
28039
World Ranking
14732
National Ranking
6155

Overview

Jerry E. Chipuk is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on Molecular Biology, Immunology, Oncology, Cancer Research, and Pathology and Forensic Medicine.

The scientist's work covers a variety of important topics including:

  • Cell death mechanisms and regulation
  • Mitochondrial Function and Pathology
  • Immune Cell Function and Interaction
  • RNA Interference and Gene Delivery
  • Cancer, Hypoxia, and Metabolism
  • Phagocytosis and Immune Regulation
  • Immunotherapy and Immune Responses

A selection of notable publications includes:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023" (2023), published in Cell Death and Differentiation
  • "PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes" (2022), published in Cell Stem Cell
  • "Mechanistic connections between mitochondrial biology and regulated cell death" (2021), published in Developmental Cell
  • "Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 + PD-1 + CD8 T cells" (2023), published in Science Immunology
  • "A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma" (2022), published in Nature Communications

Jerry E. Chipuk frequently collaborates with several other researchers. Frequent coauthors include:

  • Jesse D. Gelles
  • Emily Bernstein
  • Jarvier N. Mohammed
  • Yiyang Chen
  • Andrew Trotta

The scientist has published research in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Developmental Cell
  • Nature Communications
  • JCI Insight

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.

    Jerry E. Chipuk;Tomomi Kuwana;Lisa Bouchier-Hayes;Nathalie M. Droin

  • The BCL-2 Family Reunion

    Jerry E. Chipuk;Tudor Moldoveanu;Fabien Llambi;Melissa J. Parsons

  • BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.

    Tomomi Kuwana;Lisa Bouchier-Hayes;Jerry E. Chipuk;Christine Bonzon

  • How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

    Jerry E. Chipuk;Douglas R. Green

  • Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.

    Ann Cassidy-Stone;Jerry E. Chipuk;Elena Ingerman;Cheng Song

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario.

    J E Chipuk;L Bouchier-Hayes;D R Green

  • PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.

    Jerry E. Chipuk;Lisa Bouchier-Hayes;Lisa Bouchier-Hayes;Tomomi Kuwana;Tomomi Kuwana;Donald D. Newmeyer;Donald D. Newmeyer

  • Dissecting p53-dependent apoptosis

    J E Chipuk;D R Green

  • Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

    Jerry E. Chipuk;Gavin P. McStay;Archana Bharti;Tomomi Kuwana

  • GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

    Melanie Greter;Julie Helft;Andrew Chow;Daigo Hashimoto

  • Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool

    Stefan Jordan;Navpreet Tung;Maria Casanova-Acebes;Christie Chang

  • Do inducers of apoptosis trigger caspase-independent cell death?

    Jerry E. Chipuk;Douglas R. Green

  • Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

    Jerry E. Chipuk;Ulrich Maurer;Douglas R. Green;Martin Schuler

  • Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors

    Madhavika N. Serasinghe;Shira Y. Wieder;Thibaud T. Renault;Rana Elkholi

  • Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis.

    Diana Spierings;Gavin McStay;Maya Saleh;Cheryl Bender

  • p53 and Metabolism: Inside the TIGAR

    Douglas R. Green;Jerry E. Chipuk

  • Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

    Jerry E. Chipuk;John C. Fisher;Christopher P. Dillon;Richard W. Kriwacki

  • The androgen receptor represses transforming growth factor-β signaling through interaction with Smad3

    Jerry E. Chipuk;Susan C. Cornelius;Nicole J. Pultz;Joan S. Jorgensen

Frequent Co-Authors

Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Gyorgy Szabadkai
Gyorgy Szabadkai University College London
Donald D. Newmeyer
Donald D. Newmeyer La Jolla Institute For Allergy & Immunology
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Simone Fulda
Simone Fulda Goethe University Frankfurt
Sharad Kumar
Sharad Kumar University of Adelaide
Richard A. Knight
Richard A. Knight University College London
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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