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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
25828
World Ranking
4258
National Ranking
104

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Philippe Bouillet is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant work also in immunology and microbiology.

The scientist's work involves several subfields including molecular biology, immunology, hematology, general health professions, and epidemiology. Their main research topics focus on RNA research and splicing, RNA modifications and cancer, ubiquitin and proteasome pathways, immunotherapy and immune responses, interferon and immune responses, T-cell and B-cell immunology, and cell death mechanisms and regulation.

Some of the recent papers authored or co-authored by Philippe Bouillet include:

  • Severe Impairment of TNF Post-transcriptional Regulation Leads to Embryonic Death, 2020, published in iScience
  • Dual roles for LUBAC signaling in thymic epithelial cell development and survival, 2021, published in Cell Death and Differentiation
  • Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation, 2020, published in Cell Reports
  • ZC3H12C expression in dendritic cells is necessary to prevent lymphadenopathy of skin-draining lymph nodes, 2022, published in Immunology and Cell Biology
  • Relative importance of the anti-apoptotic versus apoptosis-unrelated functions of MCL-1 in vivo, 2025, published in Science

Frequent collaborators include Andrew J. Kueh, Andreas Strasser, Destiny Dalseno, Verena C. Wimmer, and Leonie Gibson.

Significant publication venues where Philippe Bouillet's work appears include Cell Reports, bioRxiv (Cold Spring Harbor Laboratory), HAL (Le Centre pour la Communication Scientifique Directe), iScience, and Cell Death and Differentiation.

Best Publications

  • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity.

    Philippe Bouillet;Donald Metcalf;David C. S. Huang;David M. Tarlinton

  • ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

    Hamsa Puthalakath;Lorraine A. O'Reilly;Priscilla Gunn;Lily Lee

  • Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

    Simon N. Willis;Jamie I. Fletcher;Thomas Kaufmann;Mark F. van Delft;Mark F. van Delft

  • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.

    Philippe Bouillet;Jared F. Purton;Dale I. Godfrey;Li-Chen Zhang

  • Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

    David A Hildeman;Yanan Zhu;Thomas C Mitchell;Philippe Bouillet

  • Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

    Vanessa S. Marsden;Liam O'Connor;Liam O'Connor;Lorraine A. O'Reilly;John Silke

  • Bim is a suppressor of Myc-induced mouse B cell leukemia

    Alexander Egle;Alan W. Harris;Philippe Bouillet;Suzanne Cory

  • Induction of BIM, a Proapoptotic BH3-Only BCL-2 Family Member, Is Critical for Neuronal Apoptosis

    Girish V Putcha;Krista L Moulder;Judith P Golden;Philippe Bouillet

  • XIAP discriminates between type I and type II FAS-induced apoptosis

    Philipp. Jost;Stephanie. Grabow;Stephanie. Grabow;Daniel. Gray;Mark D. McKenzie;Mark D. McKenzie

  • BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death.

    Philippe Bouillet;Andreas Strasser

  • Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

    Lorraine A. O Reilly;Lin Tai;Lily Lee;Elizabeth A. Kruse;Elizabeth A. Kruse

  • Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

    Stefan P. Glaser;Erinna F. Lee;Evelyn Trounson;Philippe Bouillet

  • Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene.

    M Oulad-Abdelghani;P Bouillet;D Décimo;A Gansmuller

  • Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

    Junya Kuroda;Hamsa Puthalakath;Mark S. Cragg;Priscilla N. Kelly;Priscilla N. Kelly

  • Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells

    Anselm Enders;Philippe Bouillet;Hamsa Puthalakath;Yuekang Xu

  • Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

    Ting Ting Tan;Kurt Degenhardt;Kurt Degenhardt;Deirdre A. Nelson;Brian Beaudoin

  • Degenerative Disorders Caused by Bcl-2 Deficiency Prevented by Loss of Its BH3-Only Antagonist Bim

    Philippe Bouillet;Suzanne Cory;Li-Chen Zhang;Andreas Strasser

  • Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.

    Peter D. Hughes;Gabrielle T. Belz;Karen A. Fortner;Ralph C. Budd

  • Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

    Stephen Malin;Shane McManus;César Cobaleda;César Cobaleda;Maria Novatchkova

  • Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix–loop–helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells

    Mohamed Boudjelal;Reshma Taneja;Shyuichiro Matsubara;Philippe Bouillet

Frequent Co-Authors

Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Lorraine A. O'Reilly
Lorraine A. O'Reilly Walter and Eliza Hall Institute of Medical Research
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Jerry M. Adams
Jerry M. Adams Walter and Eliza Hall Institute of Medical Research
Marco J. Herold
Marco J. Herold Walter and Eliza Hall Institute of Medical Research
Suzanne Cory
Suzanne Cory Walter and Eliza Hall Institute of Medical Research
Daniel H. D. Gray
Daniel H. D. Gray Walter and Eliza Hall Institute of Medical Research
John Silke
John Silke Walter and Eliza Hall Institute of Medical Research
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Pascal Dollé
Pascal Dollé Institute of Genetics and Molecular and Cellular Biology

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