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D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
13502
World Ranking
17865
National Ranking
511

Overview

Daniel H. D. Gray is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research contributions span multiple fields including Immunology and Microbiology, with a significant focus on Immunology, Molecular Biology, Oncology, Genetics, and Applied Mathematics.

Gray's research topics cover a range of areas with notable emphasis on:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Single-cell and spatial transcriptomics
  • Chronic Lymphocytic Leukemia Research
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research

The scientist has published extensively in journals such as bioRxiv (Cold Spring Harbor Laboratory), Blood, Nature Immunology, Cell Death and Differentiation, and Science Immunology. These frequent publication venues indicate a strong focus on immunological and biomedical research.

Frequent collaborators include Charis E. Teh, Tania Tan, Marie Trussart, Terence P. Speed, and David C.S. Huang, suggesting active collaboration within a broad scientific network.

Recent notable papers by Gray include:

  • Mesenchymal stromal cell apoptosis is required for their therapeutic function, 2021, Nature Communications
  • Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma, 2021, Nature Immunology
  • Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer, 2020, Clinical Cancer Research
  • Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy, 2022, Blood
  • ImmGen at 15, 2020, Nature Immunology

Gray's work integrates advanced methodologies such as single-cell and multiomics technologies, particularly in the context of immune cell behavior and cancer therapies. This includes research on the mechanisms underlying leukemia relapse, immune checkpoint modulation in cancer, and therapeutic interventions via cell apoptosis and molecular targeting.

Best Publications

  • The Immunological Genome Project: networks of gene expression in immune cells

    Tracy S P Heng;Michio W Painter;Kutlu Elpek;Veronika Lukacs-Kornek

  • XIAP discriminates between type I and type II FAS-induced apoptosis

    Philipp. Jost;Stephanie. Grabow;Stephanie. Grabow;Daniel. Gray;Mark D. McKenzie;Mark D. McKenzie

  • CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes

    Tomoo Ueno;Fumi Saito;Daniel Herbert Donald Gray;Sachiyo Kuse

  • Developmental kinetics, turnover and stimulatory capacity of thymic epithelial cells

    Daniel Herbert Donald Gray;Natalie Louise Seach;Tomoo Ueno;Morag Kertanya Milton

  • Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

    Daniel Gray;Jakub Abramson;Christophe Benoist;Diane Mathis

  • Homeostatic control of regulatory T cell diversity.

    Adrian Liston;Daniel H. D. Gray

  • CIS is a potent checkpoint in NK cell–mediated tumor immunity

    Rebecca B. Delconte;Tatiana B Kolesnik;Laura F. Dagley;Laura F. Dagley;Jai Rautela;Jai Rautela

  • Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia.

    Piers Blombery;Piers Blombery;Mary Ann Anderson;Mary Ann Anderson;Mary Ann Anderson;Jia-nan Gong;Jia-nan Gong;Rachel Thijssen;Rachel Thijssen

  • Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

    Adrian Liston;Daniel Herbert Donald Gray;Sylvie Lesage;Sylvie Lesage;Anne Louise Fletcher

  • Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.

    Emma Nolan;Emma Nolan;Peter Savas;Peter Savas;Antonia N. Policheni;Antonia N. Policheni;Phillip K. Darcy;Phillip K. Darcy

  • p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.

    Liz J. Valente;Daniel H.D. Gray;Daniel H.D. Gray;Ewa M. Michalak;Ewa M. Michalak;Josefina Pinon-Hofbauer

  • Role for CCR7 Ligands in the Emigration of Newly Generated T Lymphocytes from the Neonatal Thymus

    Tomoo Ueno;Kyoko Hara;Melissa S Willis;M A Malin

  • The transcriptional landscape of αβ T cell differentiation

    Michael Mingueneau;Taras Kreslavsky;Daniel Gray;Daniel Gray;Tracy Heng

  • Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3 + regulatory T cells

    Wim Pierson;Bénédicte Cauwe;Antonia Policheni;Antonia Policheni;Susan M Schlenner

  • Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration

    Onder Alpdogan;Onder Alpdogan;Vanessa M Hubbard;Vanessa M Hubbard;Odette M Smith;Odette M Smith;Neel Patel;Neel Patel

  • Analysis of thymic stromal cell populations using flow cytometry.

    Daniel Herbert Donald Gray;Anne Chidgey;Richard L Boyd

  • Genetic Inversion in Mast Cell-Deficient Wsh Mice Interrupts Corin and Manifests as Hematopoietic and Cardiac Aberrancy

    Peter A. Nigrovic;Peter A. Nigrovic;Daniel H.D. Gray;Tatiana Jones;Jenny Hallgren

  • Effects of Castration on Thymocyte Development in Two Different Models of Thymic Involution

    Tracy Shu Ping Heng;Gabrielle Lianne Goldberg;Daniel Herbert Donald Gray;Jayne Suzanne Sutherland

  • Generalized Resistance to Thymic Deletion in the NOD Mouse: A Polygenic Trait Characterized by Defective Induction of Bim

    Adrian Liston;Sylvie Lesage;Daniel H.D. Gray;Lorraine A. O'Reilly

  • Thymic generation and regeneration

    Jason William Gill;Mark A Malin;Jayne S Sutherland;Daniel Herbert Donald Gray

Frequent Co-Authors

Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Richard L. Boyd
Richard L. Boyd Monash University
Philippe Bouillet
Philippe Bouillet Walter and Eliza Hall Institute of Medical Research
Lorraine A. O'Reilly
Lorraine A. O'Reilly Walter and Eliza Hall Institute of Medical Research
Marco J. Herold
Marco J. Herold Walter and Eliza Hall Institute of Medical Research
Andrew W. Roberts
Andrew W. Roberts Walter and Eliza Hall Institute of Medical Research
Nicholas D. Huntington
Nicholas D. Huntington Monash University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Adrian Liston
Adrian Liston University of Cambridge

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