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Nicholas D. Huntington

Nicholas D. Huntington

D-Index & Metrics

Immunology

D-Index
66
Citations
17394
World Ranking
2742
National Ranking
110

Overview

Nicholas D. Huntington is a researcher affiliated with Monash University in Australia, with a focus on immunology and microbiology. Their academic work intersects various subfields including immunology, oncology, molecular biology, genetics, and hematology. The main topics of their research encompass immune cell function and interaction, T-cell and B-cell immunology, CAR-T cell therapy research, immunotherapy and immune responses, cancer immunotherapy and biomarkers, IL-33, ST2, and ILC pathways, as well as the role of immune cells in cancer.

Among Huntington's recent notable publications are:

  • The cancer-natural killer cell immunity cycle, 2020, published in Nature Reviews. Cancer
  • Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases, 2020, published in Frontiers in Immunology
  • Mesenchymal stromal cell apoptosis is required for their therapeutic function, 2021, published in Nature Communications
  • Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity, 2021, published in Nature Immunology
  • Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection, 2021, published in Immunity

Huntington has frequently published in several scientific outlets including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Frontiers in Immunology
  • Cell Reports
  • Nature Communications

Throughout their career, they have co-authored many papers with a number of frequent collaborators. These include Jai Rautela, Fernando Souza-Fonseca-Guimarães, Melissa J. Davis, Stephen L. Nutt, and Joseph Cursons. Their collaboration counts range up to 28 joint publications with Jai Rautela.

Best Publications

  • ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

    Hamsa Puthalakath;Lorraine A. O'Reilly;Priscilla Gunn;Lily Lee

  • Targeting natural killer cells in cancer immunotherapy

    Camille Guillerey;Camille Guillerey;Nicholas D Huntington;Nicholas D Huntington;Mark J Smyth;Mark J Smyth

  • IL-15 trans-presentation promotes human NK cell development and differentiation in vivo.

    Nicholas D. Huntington;Nicolas Legrand;Nuno L. Alves;Barbara Jaron

  • TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

    Sébastien Viel;Antoine Marçais;Fernando Souza Fonseca Guimaraes;Fernando Souza Fonseca Guimaraes;Roisin Loftus

  • Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

    Yulong Gao;Yulong Gao;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Tobias Bald;Susanna S Ng;Susanna S Ng

  • Developmental pathways that generate natural-killer-cell diversity in mice and humans

    Nicholas D. Huntington;Christian A. J. Vosshenrich;James P. Di Santo

  • The cancer–natural killer cell immunity cycle

    Nicholas D Huntington;Joseph Cursons;Jai Rautela

  • CIS is a potent checkpoint in NK cell–mediated tumor immunity

    Rebecca B. Delconte;Tatiana B Kolesnik;Laura F. Dagley;Laura F. Dagley;Jai Rautela;Jai Rautela

  • Lyn tyrosine kinase: accentuating the positive and the negative.

    Yuekang Xu;Kenneth W. Harder;Nicholas D. Huntington;Margaret L. Hibbs

  • NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation.

    Nicholas D. Huntington;Nicholas D. Huntington;Hy Tabarias;Hy Tabarias;Kirsten Fairfax;Kirsten Fairfax;Jason Brady

  • Tissue-resident memory CD8 + T cells promote melanoma-immune equilibrium in skin

    Simone L Park;Anthony Buzzai;Jai Rautela;Jyh Liang Hor

  • A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment.

    Arabella Young;Arabella Young;Shin Foong Ngiow;Shin Foong Ngiow;Shin Foong Ngiow;Yulong Gao;Yulong Gao;Ann Marie Patch

  • Functional subsets of mouse natural killer cells

    Yoshihiro Hayakawa;Nicholas D. Huntington;Stephen L. Nutt;Mark J. Smyth

  • Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

    Nicholas D Huntington;Hamsa Puthalakath;Priscilla Gunn;Edwina Naik;Edwina Naik

  • Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases.

    Yuhao Jiao;Li Wu;Nicholas D. Huntington;Xuan Zhang;Xuan Zhang

  • A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients.

    Joseph Cursons;Joseph Cursons;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Momeneh Foroutan;Momeneh Foroutan;Ashley Anderson

  • The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

    Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Joseph Cursons;Nicholas D. Huntington;Nicholas D. Huntington;Nicholas D. Huntington

  • Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

    Nicolas Legrand;Nicolas Legrand;Alexander Ploss;Alexander Ploss;Rudi Balling;Pablo D. Becker

  • Complementarity and redundancy of IL-22-producing innate lymphoid cells.

    Lucille C. Rankin;Mathilde J.H. Girard-Madoux;Cyril Seillet;Cyril Seillet;Lisa A. Mielke;Lisa A. Mielke

  • Nfil3 is required for the development of all innate lymphoid cell subsets

    Cyril Seillet;Cyril Seillet;Lucille C. Rankin;Lucille C. Rankin;Joanna R. Groom;Joanna R. Groom;Lisa A. Mielke;Lisa A. Mielke

  • Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

    Nicolas Legrand;Nicholas D. Huntington;Maho Nagasawa;Arjen Q. Bakker

Frequent Co-Authors

Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Gabrielle T. Belz
Gabrielle T. Belz University of Queensland
Stephen L. Nutt
Stephen L. Nutt Walter and Eliza Hall Institute of Medical Research
James P. Di Santo
James P. Di Santo Institut Pasteur
David M. Tarlinton
David M. Tarlinton Monash University
Wei Shi
Wei Shi Monash University
Mariapia A. Degli-Esposti
Mariapia A. Degli-Esposti Monash University
Eric Vivier
Eric Vivier Aix-Marseille University
Sandra E. Nicholson
Sandra E. Nicholson Walter and Eliza Hall Institute of Medical Research
Warren S. Alexander
Warren S. Alexander Walter and Eliza Hall Institute of Medical Research

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