World's Best Scientists 2026 revealed!
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2025
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
170
Citations
109996
World Ranking
878
National Ranking
524

Immunology

D-Index
177
Citations
121163
World Ranking
40
National Ranking
29

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2019 - Member of the National Academy of Sciences

Overview

Marco Colonna is affiliated with Washington University in St. Louis in the United States. Their research primarily spans the fields of Immunology and Microbiology, with additional work in Medicine. The main subfields of study include Immunology, Neurology, Surgery, Molecular Biology, and Epidemiology.

Their work addresses various topics related to immune system function and neurobiology. Notable research themes include Neuroinflammation and Neurodegeneration Mechanisms, Immune Cell Function and Interaction, IL-33, ST2, and ILC Pathways, Immune cells in cancer, Inflammation biomarkers and pathways, Eosinophilic Esophagitis, and T-cell and B-cell Immunology.

Frequent coauthors with whom they have collaborated extensively are Marina Cella, Siyan Cao, Susan Gilfillan, Parakkal Deepak, and José Luís Fachi.

Marco Colonna's publications appear regularly in several scientific journals and venues. Their most frequent publication venues include Gastroenterology, bioRxiv (Cold Spring Harbor Laboratory), Nature Immunology, Proceedings of the National Academy of Sciences, and The Journal of Immunology.

Recent papers by Marco Colonna include:

  • Microglia states and nomenclature: A field at its crossroads, 2022, Neuron
  • Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease, 2020, Nature Medicine
  • Negative feedback control of neuronal activity by microglia, 2020, Nature
  • Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging, 2020, Immunity
  • TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy, 2020, Cell

Marco Colonna has been recognized as a Member of the National Academy of Sciences since 2019.

Best Publications

  • A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

    Hadas Keren-Shaul;Amit Spinrad;Assaf Weiner;Assaf Weiner;Orit Matcovitch-Natan

  • Innate lymphoid cells--a proposal for uniform nomenclature.

    Hergen Spits;David Artis;Marco Colonna;Andreas Diefenbach

  • Microglia Function in the Central Nervous System During Health and Neurodegeneration.

    Marco Colonna;Oleg Butovsky

  • Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon.

    Marina Cella;David Jarrossay;Fabio Facchetti;Olga Alebardi

  • Plasmacytoid dendritic cells in immunity.

    Marco Colonna;Giorgio Trinchieri;Yong Jun Liu

  • Innate Lymphoid Cells: 10 Years On.

    Eric Vivier;David Artis;Marco Colonna;Andreas Diefenbach

  • TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

    Yaming Wang;Yaming Wang;Marina Cella;Kaitlin Mallinson;Jason D. Ulrich

  • Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.

    Axel Bouchon;Jes Dietrich;Marco Colonna

  • Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.

    Slava Epelman;Kory J. Lavine;Anna E. Beaudin;Dorothy K. Sojka

  • A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

    Marina Cella;Anja Fuchs;William Vermi;Fabio Facchetti

  • Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death

    William J. Grossman;James W. Verbsky;Winfried Barchet;Marco Colonna

  • TREM-1 amplifies inflammation and is a crucial mediator of septic shock

    Axel Bouchon;Fabio Facchetti;Markus A. Weigand;Marco Colonna

  • Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

    Aleksandra Deczkowska;Hadas Keren-Shaul;Assaf Weiner;Marco Colonna

  • Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

    Leonid Gitlin;Winfried Barchet;Susan Gilfillan;Marina Cella

  • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

    Thirumala Devi Kanneganti;Nesrin Özören;Mathilde Body-Malapel;Amal Amer

  • Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

    Diego Adhemar Jaitin;Lorenz Adlung;Christoph A. Thaiss;Assaf Weiner

  • Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.

    Marina Cella;Fabio Facchetti;Antonio Lanzavecchia;Marco Colonna

  • TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.

    Tyler K. Ulland;Wilbur M. Song;Stanley Ching Cheng Huang;Jason D. Ulrich

  • The multifaceted biology of plasmacytoid dendritic cells

    Melissa Swiecki;Marco Colonna

  • A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

    Marco Colonna;Francisco Navarro;Teresa Bellón;Manuel Llano

  • IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

    Yaming Wang;Kristy J Szretter;William Vermi;William Vermi;Susan Gilfillan

  • Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

    Yingyue Zhou;Wilbur M. Song;Prabhakar S. Andhey;Amanda Swain

  • Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4.

    C. C. Chang;R Ciubotariu;J. S. Manavalan;J. Yuan

  • CD56bright natural killer cells are present in human lymph nodes and are activated by T cell–derived IL-2: a potential new link between adaptive and innate immunity

    Todd A Fehniger;Megan A Cooper;Gerard J Nuovo;Marina Cella

Frequent Co-Authors

Marina Cella
Marina Cella Washington University in St. Louis
Susan Gilfillan
Susan Gilfillan Washington University in St. Louis
William Vermi
William Vermi University of Brescia
Fabio Facchetti
Fabio Facchetti University of Brescia
Wayne M. Yokoyama
Wayne M. Yokoyama Washington University in St. Louis
Winfried Barchet
Winfried Barchet University of Bonn
Eric Vivier
Eric Vivier Aix-Marseille University
Maxim N. Artyomov
Maxim N. Artyomov Washington University in St. Louis
David M. Holtzman
David M. Holtzman Washington University in St. Louis
Toshiyuki Takai
Toshiyuki Takai Tohoku University

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