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Biology and Biochemistry

D-Index
79
Citations
18993
World Ranking
4389
National Ranking
2137

Overview

Vincent C. Manganiello is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on biochemistry, genetics, molecular biology, and chemistry, with specific engagement in molecular biology and organic chemistry as subfields.

Their work explores topics including sirtuins and resveratrol in medicine, histone deacetylase inhibitors research, phosphodiesterase function and regulation, as well as synthesis and catalytic reactions within chemical synthesis contexts.

Recent publication venues for Vincent C. Manganiello include UNC Libraries, where they have published multiple papers. Notably, their recent works include:

  • Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases (2020, UNC Libraries)
  • Advances in targeting cyclic nucleotide phosphodiesterases (2021, UNC Libraries)

Frequent collaborators in their research encompass several scientists with repeated joint publications, including:

  • Faiyaz Ahmad
  • Hengming Ke
  • Jay H. Chung
  • Sung Jun Park
  • Andrew Philp

The range of their studies covers biochemical pathways involving phosphodiesterases and regulatory molecular mechanisms associated with aging and metabolic processes. Their contributions span topics that are relevant to both medical applications and organic chemical synthesis.

Best Publications

  • Foxp3-dependent programme of regulatory T-cell differentiation

    Marc A. Gavin;Jeffrey P. Rasmussen;Jason D. Fontenot;Valeria Vasta

  • Advances in targeting cyclic nucleotide phosphodiesterases

    Donald H Maurice;Hengming Ke;Faiyaz Ahmad;Yousheng Wang

  • Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3).

    Eva Degerman;Per Belfrage;Vincent C. Manganiello

  • Tumor Necrosis Factor-α Stimulates Lipolysis in Differentiated Human Adipocytes Through Activation of Extracellular Signal-Related Kinase and Elevation of Intracellular cAMP

    Hui H. Zhang;Melanie Halbleib;Faiyaz Ahmad;Vincent C. Manganiello

  • An effect of insulin on cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in fat cells.

    Vincent Manganiello;Martha Vaughan

  • Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness.

    Joel Moss;Peter H. Fishman;Vincent C. Manganiello;Martha Vaughan

  • Diversity in cyclic nucleotide phosphodiesterase isoenzyme families.

    Vincent C Manganiello;Taku Murata;Masato Taira;Per Belfrage

  • Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

    Silvia Masciarelli;Kathleen Horner;Chengyu Liu;Sun Hee Park

  • Clinical and molecular genetics of the phosphodiesterases (PDEs).

    Monalisa F. Azevedo;Monalisa F. Azevedo;Fabio R. Faucz;Fabio R. Faucz;Eirini Bimpaki;Anelia Horvath

  • Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family.

    Yasmin Shakur;Lena Stenson Holst;Tova Rahn Landstrom;Matthew Movsesian

  • Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase.

    Joel Moss;Vincent C. Manganiello;Martha Vaughan

  • Effects of Lipolytic and Antilipolytic Agents on Cyclic 3',5'-Adenosine Monophosphate in Fat Cells

    Vincent C. Manganiello;Ferid Murad;Martha Vaughan

  • Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation.

    E Degerman;C J Smith;H Tornqvist;V Vasta

  • Resveratrol as a calorie restriction mimetic: therapeutic implications

    Jay H. Chung;Vincent Manganiello;Jason R.B. Dyck

  • Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases.

    Rickey R. Reinhardt;Edward Chin;Jian Zhou;Masato Taira

  • A Simple, Sensitive Protein-binding Assay for Guanosine 3′:5′-Monophosphate

    Ferid Murad;Vincent Manganiello;Martha Vaughan

  • Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase.

    Elisabetta Meacci;Masato Taira;Malcolm Moos;Carolyn J. Smith

  • Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases

    F Hirata;R del Carmine;C A Nelson;J Axelrod

  • Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B–null mice

    Young Hun Choi;Sunhee Park;Steven Hockman;Emilia Zmuda-Trzebiatowska

  • Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase.

    M Taira;S C Hockman;J C Calvo;P Belfrage

Frequent Co-Authors

Eva Degerman
Eva Degerman Lund University
Martha Vaughan
Martha Vaughan National Institutes of Health
Per Belfrage
Per Belfrage Lund University
Joel Moss
Joel Moss National Institutes of Health
Ronald I. Clyman
Ronald I. Clyman University of California, San Francisco
Peter H. Backx
Peter H. Backx York University
Bo Ahrén
Bo Ahrén Lund University
Fusao Hirata
Fusao Hirata Johns Hopkins University
Peter H. Fishman
Peter H. Fishman National Institutes of Health
Oksana Gavrilova
Oksana Gavrilova National Institutes of Health

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