2026 Alexander Y. Rudensky: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	137	176	163	117	108	329	102674
Medicine	138	1794	1667	1026	941	342	104996

Research.com Recognitions

2015 - Fellow of the American Academy of Arts and Sciences
2015 - Member of the National Academy of Medicine (NAM)
2012 - Member of the National Academy of Sciences
1999 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

Alexander Y. Rudensky is affiliated with the Memorial Sloan Kettering Cancer Center in the United States and has an extensive research record focused on immunology and microbiology. Their work spans several subfields, including immunology, molecular biology, oncology, surgery, and cancer research.

Their research mainly addresses the following topics:

Immune Cell Function and Interaction
T-cell and B-cell Immunology
Immunotherapy and Immune Responses
IL-33, ST2, and ILC Pathways
Single-cell and spatial transcriptomics
CAR-T cell therapy research
Immune cells in cancer

Alexander Y. Rudensky has published numerous papers in prominent scientific journals. Recent significant publications include:

"Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells" (2020) in Nature
"Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity" (2021) in Science
"Principles of regulatory T cell function" (2023) in Immunity
"Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota" (2022) in Nature
"Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma" (2022) in Science Immunology

Their research has been regularly published in high-impact venues, including:

bioRxiv (Cold Spring Harbor Laboratory)
Immunity
Nature Immunology
The Journal of Experimental Medicine
Science

Frequent collaborators in Alexander Y. Rudensky's work include:

Christina S. Leslie
Zhong-Min Wang
Yuri Pritykin
Joris van der Veeken
Michail Schizas

Their research is grounded in the fields of immunology and microbiology, with 124 publications attributed to these areas. Additional contributions fall under molecular biology, oncology, surgery, and cancer research. The body of their work reflects a focus on immune system mechanisms, particularly regulatory T cell biology and immune response pathways relevant to cancer and infectious disease.

Alexander Y. Rudensky has received several honors, including:

Fellow of the American Academy of Arts and Sciences (2015)
Member of the National Academy of Medicine (NAM) (2015)
Member of the National Academy of Sciences (2012)
AAI-BD Biosciences Investigator Award from the American Association of Immunologists (1999)

Best Publications

Foxp3 programs the development and function of CD4 + CD25 + regulatory T cells

Jason D. Fontenot;Marc A. Gavin;Alexander Y. Rudensky

10088
Citations
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Nicholas Arpaia;Clarissa Campbell;Xiying Fan;Stanislav Dikiy

4769
Citations
Regulatory T Cells: Mechanisms of Differentiation and Function

Steven Z. Josefowicz;Li-Fan Lu;Alexander Y. Rudensky

3281
Citations
Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Jason D. Fontenot;Jeffrey P. Rasmussen;Luke M. Williams;James L. Dooley

2887
Citations
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function.

Liang Zhou;Jared E. Lopes;Jared E. Lopes;Mark M. W. Chong;Ivaylo I. Ivanov

2648
Citations
A function for interleukin 2 in Foxp3-expressing regulatory T cells

Jason D Fontenot;Jason D Fontenot;Jeffrey P Rasmussen;Marc A Gavin;Alexander Y Rudensky

2283
Citations
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice.

Jeong M Kim;Jeffrey P Rasmussen;Alexander Y Rudensky

2175
Citations
A comparative encyclopedia of DNA elements in the mouse genome

Feng Yue;Feng Yue;Yong Cheng;Alessandra Breschi;Jeff Vierstra

2142
Citations
Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment.

Elham Azizi;Ambrose J. Carr;Ambrose J. Carr;George Plitas;Andrew E. Cornish

2037
Citations
Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

Yuri P. Rubtsov;Jeffrey P. Rasmussen;Emil Y. Chi;Jason Fontenot

1833
Citations
Foxp3-dependent programme of regulatory T-cell differentiation

Marc A. Gavin;Jeffrey P. Rasmussen;Jason D. Fontenot;Valeria Vasta

1452
Citations
A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

Jason D Fontenot;Alexander Y Rudensky

1384
Citations
Sequence analysis of peptides bound to MHC class II molecules

Alexander Yu Rudensky;Paula Preston-Hurlburt;Soon-Cheol Hong;Avlin Barlow

1374
Citations
TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

Julien C. Marie;John James Letterio;Marc Gavin;Alexander Y. Rudensky

1370
Citations
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Ye Zheng;Steven Josefowicz;Steven Josefowicz;Ashutosh Chaudhry;Ashutosh Chaudhry;Xiao P. Peng

1349
Citations
Th17 and regulatory T cells in mediating and restraining inflammation.

Dan R. Littman;Alexander Y. Rudensky

1319
Citations
CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

Ashutosh Chaudhry;Dipayan Rudra;Dipayan Rudra;Piper Treuting;Robert M. Samstein

1208
Citations
In vivo analysis of dendritic cell development and homeostasis

Kang Liu;Gabriel D. Victora;Tanja A. Schwickert;Pierre Guermonprez

1181
Citations
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3

Luke M Williams;Alexander Y Rudensky

1142
Citations
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development.

Marc A. Gavin;Troy R. Torgerson;Evan Houston;Paul deRoos

1129
Citations
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells

Ye Zheng;Steven Z. Josefowicz;Arnold Kas;Tin-Tin Chu

1087
Citations

Frequent Co-Authors

Piper M. Treuting University of Washington

Christina S. Leslie Memorial Sloan Kettering Cancer Center

Charles A. Janeway Yale University

Bruce R. Blazar University of Minnesota

Dan R. Littman New York University

Dmitriy M. Chudakov Pirogov Russian National Research Medical University

Andrew G. Farr University of Washington

Arlene H. Sharpe Harvard University

Randolph J. Noelle Dartmouth College

Mark Groudine Fred Hutchinson Cancer Research Center

External Links

Personal website of Alexander Y. Rudensky

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