H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 102 Citations 35,216 223 World Ranking 245 National Ranking 160

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Gene
  • Cytokine

Immunology, CD40, Antigen, Immune system and T cell are his primary areas of study. Randolph J. Noelle has researched Immunology in several fields, including Cytotoxic T cell and Cancer research. His CD40 research incorporates elements of Antigen-presenting cell, Antibody, B cell, Molecular biology and Cell biology.

His Antigen study combines topics in areas such as Receptor, Transplantation and T-cell receptor. His Immune system research includes elements of Signal transduction and Monoclonal antibody. Randolph J. Noelle combines subjects such as Interferon gamma and Lymphocyte with his study of T cell.

His most cited work include:

  • The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome (778 citations)
  • Molecular mechanism and function of CD40/CD40L engagement in the immune system. (771 citations)
  • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells (758 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Immunology, CD40, Immune system, Cell biology and T cell. His Immunology study typically links adjacent topics like Transplantation. His CD40 research is multidisciplinary, incorporating perspectives in Molecular biology, Internal medicine, Germinal center and Immune tolerance.

His Cell biology research incorporates themes from B-cell receptor, Retinoic acid, Cellular differentiation and Immunoglobulin class switching. His research on T cell also deals with topics like

  • Cytotoxic T cell together with Interleukin 2,
  • CD8, which have a strong connection to Bone marrow. In his research on the topic of Antigen, Cell is strongly related with Receptor.

He most often published in these fields:

  • Immunology (82.04%)
  • CD40 (39.01%)
  • Immune system (39.01%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (82.04%)
  • Immune system (39.01%)
  • Cell biology (31.27%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Immunology, Immune system, Cell biology, T cell and Cancer research. His Immunology study frequently links to other fields, such as Cytotoxic T cell. Randolph J. Noelle has included themes like CD40, Inflammation, Internal medicine, Myeloid and Antibody in his Immune system study.

His study looks at the intersection of CD40 and topics like Endocrinology with Receptor. His Cell biology research includes themes of Tolerance induction and Retinoic acid. His study on T cell also encompasses disciplines like

  • Monoclonal antibody, which have a strong connection to Molecular biology,
  • Suppressor that connect with fields like Ipilimumab and Disease.

Between 2012 and 2021, his most popular works were:

  • VISTA Regulates the Development of Protective Antitumor Immunity. (231 citations)
  • VISTA Is an Immune Checkpoint Molecule for Human T Cells (219 citations)
  • B7 family checkpoint regulators in immune regulation and disease (191 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Cytokine

His scientific interests lie mostly in Immunology, Immune system, T cell, Signal transduction and Retinoic acid. Randolph J. Noelle regularly ties together related areas like Cancer research in his Immunology studies. He interconnects Internal medicine and Antigen in the investigation of issues within Immune system.

His Internal medicine research integrates issues from Endocrinology and CD40. His T cell research is multidisciplinary, incorporating elements of CXCL10 and Priming. His Signal transduction study integrates concerns from other disciplines, such as Tumor necrosis factor alpha and Inflammation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

Randolph J. Noelle;Meenakshi Roy;David M. Shepherd;Ivan Stamenkovic.
Proceedings of the National Academy of Sciences of the United States of America (1992)

1139 Citations

BCMA Is Essential for the Survival of Long-lived Bone Marrow Plasma Cells

Brian P. O'Connor;Vanitha S. Raman;Loren D. Erickson;W. James Cook.
Journal of Experimental Medicine (2004)

1110 Citations

Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism

David C. Gondek;Li-Fan Lu;Sergio A. Quezada;Shimon Sakaguchi.
Journal of Immunology (2005)

1088 Citations

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

Alejandro Aruffo;Alejandro Aruffo;Mary Farrington;Diane Hollenbaugh;Xu Li.
Cell (1993)

923 Citations

All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

Micah J. Benson;Karina Pino-Lagos;Mario Rosemblatt;Randolph J. Noelle.
Journal of Experimental Medicine (2007)

907 Citations

Visualization of Specific B and T Lymphocyte Interactions in the Lymph Node

Paul Garside;Elizabeth Ingulli;Rebecca R. Merica;Julia G. Johnson.
Science (1998)

894 Citations

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

Melanie Greter;Frank L Heppner;Maria P Lemos;Bernhard M Odermatt.
Nature Medicine (2005)

858 Citations

Mast cells are essential intermediaries in regulatory T-cell tolerance.

Li Fan Lu;Evan F. Lind;David C. Gondek;Kathy A. Bennett.
Nature (2006)

783 Citations

Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

Fiona H. Durie;Roy A. Fava;Teresa M. Foy;Alejandro Aruffo.
Science (1993)

767 Citations

CD40/CD154 interactions at the interface of tolerance and immunity

Sergio A. Quezada;Lamis Z. Jarvinen;Evan F. Lind;Randolph J. Noelle.
Annual Review of Immunology (2004)

748 Citations

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