D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 51 Citations 16,046 92 World Ranking 2625 National Ranking 214

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Gene
  • Immune system

Sergio A. Quezada spends much of his time researching Immunology, T cell, Immunotherapy, Antigen and Immune system. His Immunology research incorporates elements of Blockade and Cancer research, Melanoma. Sergio A. Quezada combines subjects such as CTLA-4 and Antibody with his study of Cancer research.

His study ties his expertise on Cytotoxic T cell together with the subject of T cell. Sergio A. Quezada works mostly in the field of Immunotherapy, limiting it down to topics relating to Monoclonal antibody and, in certain cases, Downregulation and upregulation, K562 cells and Peripheral tolerance, as a part of the same area of interest. His specific area of interest is Antigen, where he studies CD8.

His most cited work include:

  • Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade (1503 citations)
  • Tracking the Evolution of Non–Small-Cell Lung Cancer (977 citations)
  • Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma. (911 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Immunology, Immune system, Cancer research, Immunotherapy and T cell. His Immunology study frequently links to related topics such as Blockade. His work carried out in the field of Immune system brings together such families of science as Cancer cell and Cancer.

His Cancer research research is multidisciplinary, relying on both Mutation, Epitope, Antibody, Lung cancer and Effector. Sergio A. Quezada studied Immunotherapy and Melanoma that intersect with Immunogenicity. His T cell study combines topics in areas such as Cytotoxic T cell and CD8, Antigen.

He most often published in these fields:

  • Immunology (44.97%)
  • Immune system (37.58%)
  • Cancer research (32.89%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cancer research (32.89%)
  • Immunotherapy (33.56%)
  • CD8 (16.11%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Immunotherapy, CD8, Immune system and Tumor microenvironment. His Cancer research research includes themes of IL-2 receptor, Phenotype, Antigen, Immunogenicity and Lung cancer. Sergio A. Quezada has included themes like Interleukin 12, Cytotoxic T cell and Cell-mediated cytotoxicity in his Immunotherapy study.

His research integrates issues of T cell, T-cell receptor and Bone marrow in his study of CD8. His T cell research is multidisciplinary, incorporating elements of Acquired immune system and Melanoma. His Immune system study integrates concerns from other disciplines, such as Internal medicine, Evolutionary landscape, Epigenetics and Oncology.

Between 2019 and 2021, his most popular works were:

  • Geospatial immune variability illuminates differential evolution of lung adenocarcinoma (43 citations)
  • Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells. (26 citations)
  • Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition (19 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Gene
  • Immune system

Sergio A. Quezada focuses on Cancer research, Immunotherapy, Antigen, Immune system and CD8. His work deals with themes such as Cytotoxic T cell, Granzyme B, Melanoma, Cell biology and Interleukin 2, which intersect with Immunotherapy. His studies deal with areas such as Cell, Lung cancer, Transcription factor and Interferon as well as Cytotoxic T cell.

His Antigen research includes elements of Tumor microenvironment, Cancer cell, Lymphocyte and Adenocarcinoma. His Immune system study integrates concerns from other disciplines, such as Carcinoma, Pathology and Epigenetics. His CD8 study is concerned with Immunology in general.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Nicholas McGranahan;Nicholas McGranahan;Andrew J. S. Furness;Rachel Rosenthal;Sofie Ramskov.
Science (2016)

1822 Citations

Tracking the Evolution of Non–Small-Cell Lung Cancer

Mariam Jamal-Hanjani;Gareth A. Wilson;Nicholas McGranahan;Nicolai Juul Birkbak.
The New England Journal of Medicine (2017)

1229 Citations

Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism

David C. Gondek;Li-Fan Lu;Sergio A. Quezada;Shimon Sakaguchi.
Journal of Immunology (2005)

1088 Citations

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

Tyler R. Simpson;Tyler R. Simpson;Tyler R. Simpson;Fubin Li;Welby Montalvo-Ortiz;Manuel A. Sepulveda.
Journal of Experimental Medicine (2013)

981 Citations

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

Karl S. Peggs;Sergio A. Quezada;Cynthia A. Chambers;Alan J. Korman.
Journal of Experimental Medicine (2009)

876 Citations

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Christopher Abbosh;Nicolai J. Birkbak;Nicolai J. Birkbak;Gareth A. Wilson;Gareth A. Wilson;Mariam Jamal-Hanjani.
Nature (2017)

825 Citations

CD40/CD154 interactions at the interface of tolerance and immunity

Sergio A. Quezada;Lamis Z. Jarvinen;Evan F. Lind;Randolph J. Noelle.
Annual Review of Immunology (2004)

748 Citations

Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

Sergio A. Quezada;Tyler R. Simpson;Karl S. Peggs;Taha Merghoub.
Journal of Experimental Medicine (2010)

720 Citations

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

Sergio A. Quezada;Karl S. Peggs;Michael A. Curran;James P. Allison.
Journal of Clinical Investigation (2006)

667 Citations

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

Santiago Zelenay;Annemarthe G. van der Veen;Jan P. Böttcher;Kathryn J. Snelgrove.
Cell (2015)

600 Citations

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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