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Biology and Biochemistry

D-Index
92
Citations
52376
World Ranking
2160
National Ranking
1168

Medicine

D-Index
93
Citations
53274
World Ranking
10660
National Ranking
5480

Overview

Zoltan Szallasi is affiliated with Boston Children's Hospital in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a specific focus on molecular biology and oncology. They have contributed extensively to cancer research, particularly in the areas of DNA repair mechanisms and cancer genomics and diagnostics.

The main topics addressed in Szallasi's work include:

  • DNA Repair Mechanisms
  • Cancer Genomics and Diagnostics
  • PARP inhibition in cancer therapy
  • Cancer Immunotherapy and Biomarkers
  • Bladder and Urothelial Cancer Treatments
  • Immunotherapy and Immune Responses
  • Epigenetics and DNA Methylation

Szallasi has published in several prominent scientific venues with notable frequency. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Precision Oncology
  • Clinical Cancer Research
  • Nature Communications
  • Nature Medicine

Some of their recent papers are:

  • "Pervasive chromosomal instability and karyotype order in tumour evolution," 2020, Nature
  • "Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage," 2020, Science
  • "Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations," 2020, Clinical Cancer Research
  • "CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer," 2023, Nature Communications
  • "A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer," 2022, Nature Cancer

Frequent co-authors of Szallasi include:

  • Zsófia Sztupinszki
  • István Csabai
  • Judit Börcsök
  • Miklós Dióssy
  • Kent W. Mouw

The main fields of study for Szallasi encompass biochemistry, genetics, and molecular biology with a total of 105 publications, alongside 98 publications in medicine. Their subfields of study reflect a concentration in molecular biology, oncology, and cancer research with additional contributions to pulmonary and respiratory medicine as well as surgery.

Best Publications

  • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

    Marco Gerlinger;Andrew J. Rowan;Stuart Horswell;James Larkin

  • An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients.

    Balazs Györffy;Andras Lanczky;Aron C. Eklund;Carsten Denkert

  • The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

    Leming Shi;Laura H. Reid;Wendell D. Jones;Richard Shippy

  • Tracking the Evolution of Non–Small-Cell Lung Cancer

    Mariam Jamal-Hanjani;Gareth A. Wilson;Nicholas McGranahan;Nicolai Juul Birkbak

  • Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

    Christopher Abbosh;Nicolai J. Birkbak;Nicolai J. Birkbak;Gareth A. Wilson;Gareth A. Wilson;Mariam Jamal-Hanjani

  • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

    Scott L Carter;Aron C Eklund;Aron C Eklund;Isaac S Kohane;Lyndsay N Harris

  • Robustness of cellular functions

    Jörg Stelling;Uwe Sauer;Zoltan Szallasi;Francis J. Doyle

  • Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer

    Daniel P. Silver;Andrea L. Richardson;Aron C. Eklund;Zhigang C. Wang

  • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

    Elza C. de Bruin;Nicholas McGranahan;Nicholas McGranahan;Richard Mitter;Max Salm

  • Neoantigen-directed immune escape in lung cancer evolution

    Rachel Rosenthal;Rachel Rosenthal;Elizabeth Larose Cadieux;Roberto Salgado;Maise Al Bakir

  • Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer.

    Melinda L. Telli;Kirsten M. Timms;Julia Reid;Bryan Hennessy

  • Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients.

    Balázs Győrffy;András Lánczky;Zoltán Szállási

  • Reliability and reproducibility issues in DNA microarray measurements

    Sorin Draghici;Purvesh Khatri;Aron C. Eklund;Zoltan Szallasi

  • Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data

    Francesco Favero;Tejal Joshi;Andrea Marion Marquard;Nicolai Juul Birkbak

  • Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

    Nicholas McGranahan;Nicholas McGranahan;Francesco Favero;Elza C. de Bruin;Nicolai Juul Birkbak;Nicolai Juul Birkbak

  • Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents

    Nicolai J. Birkbak;Nicolai J. Birkbak;Zhigang C. Wang;Zhigang C. Wang;Ji Young Kim;Aron C. Eklund

  • Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

    Samra Turajlic;Samra Turajlic;Hang Xu;Kevin Litchfield;Andrew Rowan

  • Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.

    K Ozawa;Z Szallasi;M G Kazanietz;P M Blumberg

  • Chromosomal Instability Confers Intrinsic Multidrug Resistance

    Alvin J. X. Lee;David Endesfelder;Andrew J. Rowan;Axel Walther

  • Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

    Thomas J. Mitchell;Samra Turajlic;Andrew Rowan;David Nicol

Frequent Co-Authors

Charles Swanton
Charles Swanton The Francis Crick Institute
István Csabai
István Csabai Eötvös Loránd University
Peter M. Blumberg
Peter M. Blumberg National Institutes of Health
Andrea L. Richardson
Andrea L. Richardson Johns Hopkins University
Nicholas McGranahan
Nicholas McGranahan University College London
Jörg Stelling
Jörg Stelling ETH Zurich
Matthew L. Freedman
Matthew L. Freedman Harvard University
James Larkin
James Larkin Royal Marsden NHS Foundation Trust
Sine Reker Hadrup
Sine Reker Hadrup Technical University of Denmark
Peter Van Loo
Peter Van Loo The Francis Crick Institute

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