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Nicholas W. Gale

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
32984
World Ranking
12244
National Ranking
5233

Nicholas W. Gale publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Nicholas W. Gale sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 100 publications — 5th percentile

5% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Nicholas W. Gale D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Nicholas W. Gale sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Nicholas W. Gale is affiliated with Regeneron in the United States. Their research spans Medicine and Biochemistry, Genetics and Molecular Biology, with specific focus on subfields including Physiology, Molecular Biology, Oncology, Cognitive Neuroscience, and Renewable Energy, Sustainability and the Environment.

The scientist has contributed to several topics within these fields, notably:

  • Mechanisms of cancer metastasis
  • Peptidase Inhibition and Analysis
  • Lysosomal Storage Disorders Research
  • Metalloenzymes and iron-sulfur proteins
  • Cellular transport and secretion
  • Calcium signaling and nucleotide metabolism
  • Glycogen Storage Diseases and Myoclonus

Their publication record includes work in diverse venues, reflecting a multidisciplinary approach. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Molecular Genetics
  • Molecular Therapy
  • Mathematical Neuroscience and Applications
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Selected recent publications by Nicholas W. Gale highlight their engagement with topics across molecular biology and neuroscience:

  • Analysis of Activity Dependent Development of Topographic Maps in Neural Field Theory with Short Time Scale Dependent Plasticity, 2022, Mathematical Neuroscience and Applications
  • Targeted delivery of acid alpha-glucosidase corrects skeletal muscle phenotypes in Pompe disease mice, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Functional modeling of NMIHBA-causing PRUNE1 variants reveals a requirement for its exopolyphosphatase activity, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • NMIHBA results from hypomorphic PRUNE1 variants that lack short-chain exopolyphosphatase activity, 2020, Human Molecular Genetics
  • Cell type-selective targeted delivery of a recombinant lysosomal enzyme for enzyme therapies, 2021, Molecular Therapy

Coauthorship patterns indicate collaboration with multiple researchers over a range of projects. Frequent co-authors include:

  • Aris N. Economides
  • Yajun Tang
  • Andrew Murphy
  • Harikiran Nistala
  • John Dronzek

Best Publications

  • Vascular-specific growth factors and blood vessel formation

    George D. Yancopoulos;Samuel Davis;Nicholas W. Gale;John S. Rudge

  • Recognition of single-stranded RNA viruses by Toll-like receptor 7

    Jennifer M. Lund;Lena Alexopoulou;Ayuko Sato;Margaret Karow

  • Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

    Ralf H. Adams;George A. Wilkinson;Cornelia Weiss;Francesca Diella

  • Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

    Irene Noguera-Troise;Christopher Daly;Nicholas J. Papadopoulos;Sandra Coetzee

  • Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

    Nicholas W. Gale;Gavin Thurston;Sean F. Hackett;Roumiana Renard

  • CD133 expression is not restricted to stem cells, and both CD133 + and CD133 – metastatic colon cancer cells initiate tumors

    Sergey V. Shmelkov;Jason M. Butler;Andrea T. Hooper;Adilia Hormigo

  • Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation.

    Ulrike Fiedler;Yvonne Reiss;Marion Scharpfenecker;Verena Grunow

  • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development

    Nicholas W. Gale;George D. Yancopoulos

  • Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

    Nicholas W Gale;Sacha J Holland;David M Valenzuela;Ann Flenniken

  • Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

    P. Chardin;J. H. Camonis;N. W. Gale;L. Van Aelst

  • Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.

    Samuel Davis;Nicholas W. Gale;Thomas H. Aldrich;Peter C. Maisonpierre

  • Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting.

    I. B. Lobov;R. A. Renard;N. Papadopoulos;N. W. Gale

  • EphB receptors interact with NMDA receptors and regulate excitatory synapse formation.

    Matthew B Dalva;Mari A Takasu;Michael Z Lin;Steven M Shamah

  • High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

    David M Valenzuela;Andrew J Murphy;David Frendewey;Nicholas W Gale

  • Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

    Nicholas W. Gale;Melissa G. Dominguez;Irene Noguera;Li Pan

  • Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

    Nicholas W. Gale;Susan Kaplan;Eve J. Lowenstein;Joseph Schlessinger

  • Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

    Sacha J. Holland;Nicholas W. Gale;Geraldine Mbamalu;George D. Yancopoulos

  • PDZ Proteins Bind, Cluster, and Synaptically Colocalize with Eph Receptors and Their Ephrin Ligands

    Richard Torres;Bonnie L Firestein;Hualing Dong;Jeff Staudinger

  • Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone

    Joanne C. Conover;Joanne C. Conover;Fiona Doetsch;Jose-Manuel Garcia-Verdugo;Nicholas W. Gale

  • Generation of functional multipotent adult stem cells from GPR125 + germline progenitors

    Marco Seandel;Marco Seandel;Daylon James;Sergey V. Shmelkov;Ilaria Falciatori

Frequent Co-Authors

George D. Yancopoulos
George D. Yancopoulos Regeneron (United States)
David M. Valenzuela
David M. Valenzuela Regeneron (United States)
Andrew J. Murphy
Andrew J. Murphy St. Jude Children's Research Hospital
Stanley J. Wiegand
Stanley J. Wiegand Regeneron (United States)
Aris N. Economides
Aris N. Economides Regeneron (United States)
Tony Pawson
Tony Pawson University of Toronto
Mark Henkemeyer
Mark Henkemeyer The University of Texas Southwestern Medical Center
Yuichi Oike
Yuichi Oike Kumamoto University
Dafna Bar-Sagi
Dafna Bar-Sagi New York University
James R. Lupski
James R. Lupski Baylor College of Medicine

External Links

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Best Scientists Citing Nicholas W. Gale

Andrew J. Murphy

Andrew J. Murphy

St. Jude Children's Research Hospital

Publications: 155

George D. Yancopoulos

George D. Yancopoulos

Regeneron (United States)

Publications: 141

Kari Alitalo

Kari Alitalo

University of Helsinki

Publications: 110

Elena B. Pasquale

Elena B. Pasquale

Discovery Institute

Publications: 93

Mark Henkemeyer

Mark Henkemeyer

The University of Texas Southwestern Medical Center

Publications: 82

David M. Valenzuela

David M. Valenzuela

Regeneron (United States)

Publications: 82

Tony Pawson

Tony Pawson

University of Toronto

Publications: 75

Hellmut G. Augustin

Hellmut G. Augustin

Heidelberg University

Publications: 64

Ralf H. Adams

Ralf H. Adams

Max Planck Society

Publications: 55

Anne Eichmann

Anne Eichmann

Yale University

Publications: 54

Peter Carmeliet

Peter Carmeliet

KU Leuven

Publications: 52

Aris N. Economides

Aris N. Economides

Regeneron (United States)

Publications: 51

Gou Young Koh

Gou Young Koh

Korea Advanced Institute of Science and Technology

Publications: 49

Shizuo Akira

Shizuo Akira

Osaka University

Publications: 48

Rüdiger Klein

Rüdiger Klein

Max Planck Society

Publications: 47

Andrew W. Boyd

Andrew W. Boyd

University of Queensland

Publications: 46

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