2026 Andrew J. Murphy: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	118	354	326	225	204	524	56037
Medicine	119	3873	3626	2119	1961	556	56562

Overview

Andrew J. Murphy is affiliated with St. Jude Children's Research Hospital in the United States. Their research contributions primarily fall within the field of Medicine, with a particular focus on Immunology, Physiology, Oncology, Molecular Biology, and Surgery.

Their recent papers illustrate work on varied topics, including infectious diseases, obesity genetics, and antibody therapies. Notable publications include:

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies, 2020, Science
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail, 2020, Science
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters, 2020, Science
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity, 2021, Science
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies, 2021, Cell

The primary topics of work covered by Murphy encompass multiple aspects of immune function and respiratory diseases, including:

Immune Cell Function and Interaction
Immunotherapy and Immune Responses
CAR-T cell therapy research
Asthma and respiratory diseases
T-cell and B-cell Immunology
Allergic Rhinitis and Sensitization
SARS-CoV-2 and COVID-19 Research

The frequent coauthors that Murphy has worked with include:

George D. Yancopoulos
Matthew A. Sleeman
Jamie Orengo
William C. Olson
Wei Keat Lim

Among the common publication venues for Murphy's research, the following stand out:

Radiopaedia.org
Science Translational Medicine
Journal of Allergy and Clinical Immunology
bioRxiv (Cold Spring Harbor Laboratory)
Science Immunology

This body of work spans a broad spectrum of biomedical research emphasizing immune system mechanisms, antibody therapies, and respiratory health concerns. The combination of collaboration and publication venues demonstrates engagement with both clinical and translational research communities.

Best Publications

Regulation of the Germinal Center Response by MicroRNA-155

To-Ha Thai;Dinis Pedro Calado;Stefano Casola;K. Mark Ansel

1870
Citations
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

Julian D. Gillmore;Ed Gane;Jorg Taubel;Justin Kao

1516
Citations
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.

David B. Lombard;Frederick W. Alt;Hwei Ling Cheng;Jakob Bunkenborg

1413
Citations
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

Marcia C. Haigis;Raul Mostoslavsky;Kevin M. Haigis;Kamau Fahie

1392
Citations
Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies.

Alina Baum;Benjamin O. Fulton;Elzbieta Wloga;Richard Copin

1340
Citations
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.

Johanna Hansen;Alina Baum;Kristen E. Pascal;Vincenzo Russo

1281
Citations
CD133 expression is not restricted to stem cells, and both CD133 + and CD133 – metastatic colon cancer cells initiate tumors

Sergey V. Shmelkov;Jason M. Butler;Andrea T. Hooper;Adilia Hormigo

1154
Citations
Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

Lauren A. Zenewicz;George D. Yancopoulos;David M. Valenzuela;Andrew J. Murphy

1127
Citations
Methods of Modifying Eukaryotic Cells

Andrew J. Murphy;George D. Yancopoulos

1118
Citations
Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation.

Lauren A. Zenewicz;George D. Yancopoulos;David M. Valenzuela;Andrew J. Murphy

918
Citations
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

Frederick E Dewey;Viktoria Gusarova;Richard L Dunbar;Colm T O'Dushlaine

875
Citations
RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes.

Yurong Xin;Jinrang Kim;Haruka Okamoto;Min Ni

850
Citations
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

Samuel Huber;Nicola Gagliani;Lauren A. Zenewicz;Francis J. Huber

796
Citations
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease

Noura S. Abul-Husn;Xiping Cheng;Alexander H. Li;Yurong Xin

786
Citations
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M Valenzuela;Andrew J Murphy;David Frendewey;Nicholas W Gale

774
Citations
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Nicholas W. Gale;Melissa G. Dominguez;Irene Noguera;Li Pan

770
Citations
High-Density Lipoprotein Reduces the Human Monocyte Inflammatory Response

Andrew J. Murphy;Kevin J. Woollard;Anh Hoang;Nigora Mukhamedova

607
Citations
Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

Frederick E. Dewey;Viktoria Gusarova;Colm O'Dushlaine;Omri Gottesman

587
Citations
Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis.

Prabhakara R. Nagareddy;Andrew J. Murphy;Roslynn A. Stirzaker;Yunying Hu

584
Citations
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

Frederick E. Dewey;Michael F. Murray;John D. Overton;Lukas Habegger

582
Citations
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Kai Deng;Mihaela Pertea;Anthony Rongvaux;Leyao Wang

579
Citations
Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice

Tong Jin Zhao;Guosheng Liang;Robert Lin Li;Xuefen Xie

564
Citations
ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Andrew J. Murphy;Mani Akhtari;Sonia Tolani;Tamara Pagler

555
Citations

Frequent Co-Authors

George D. Yancopoulos Regeneron (United States)

David M. Valenzuela Regeneron (United States)

Jesper Gromada Regeneron (United States)

Aris N. Economides Regeneron (United States)

Brian Zambrowicz Regeneron (United States)

Alan R. Tall Columbia University

William C. Olson Regeneron (United States)

Richard A. Flavell Yale University

Mark A. Febbraio Monash University

Nicholas W. Gale Regeneron (United States)

External Links

Personal website of Andrew J. Murphy

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