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Microbiology

D-Index
64
Citations
17703
World Ranking
2586
National Ranking
1043

Overview

William C. Olson is affiliated with Regeneron in the United States, focusing on research that spans medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work primarily addresses the fields of oncology, immunology, molecular biology, radiology, nuclear medicine and imaging, as well as biomedical engineering.

The scientist's publications concentrate on topics related to monoclonal and polyclonal antibodies research, CAR-T cell therapy research, immunotherapy and immune responses, cancer immunotherapy and biomarkers, immune cell function and interaction, cytokine signaling pathways and interactions, and the complement system in diseases.

Among Olson's recent papers are the following:

  • Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail, 2020, Science
  • A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies, 2020, Science Translational Medicine
  • Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning, 2021, Scientific Reports
  • Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy, 2020, Science Translational Medicine
  • Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response, 2021, Journal of Allergy and Clinical Immunology

Frequent co-authors who have collaborated with Olson include:

  • Matthew C. Franklin
  • Andrew Murphy
  • Tammy Huang
  • George D. Yancopoulos
  • Ashique Rafique

Olson's research has been published predominantly in various venues, with the most frequent publication outlets listed as:

  • Science Translational Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cancer Therapeutics
  • Cancer Research
  • Nature Communications

Best Publications

  • CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

    Alexandra Trkola;Tatjana Dragic;James Arthos;James M. Binley

  • Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.

    Johanna Hansen;Alina Baum;Kristen E. Pascal;Vincenzo Russo

  • A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

    Robert Pejchal;Katie J. Doores;Katie J. Doores;Laura M. Walker;Reza Khayat

  • A Recombinant Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure

    James M. Binley;Rogier W. Sanders;Brian Clas;Norbert Schuelke

  • A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease

    Noura S. Abul-Husn;Xiping Cheng;Alexander H. Li;Yurong Xin

  • Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1

    Rogier W. Sanders;Mika Vesanen;Norbert Schuelke;Aditi Master

  • L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus.

    Jason P. Gardner;Robert J. Durso;Robert R. Arrigale;Gerald P. Donovan

  • Selective Interactions of Polyanions with Basic Surfaces on Human Immunodeficiency Virus Type 1 gp120

    Maxime Moulard;Hugues Lortat-Jacob;Isabelle Mondor;Guillaume Roca

  • The homodimer of prostate-specific membrane antigen is a functional target for cancer therapy

    Norbert Schülke;Olga A. Varlamova;Gerald P. Donovan;Dangshe Ma

  • Potent, Broad-Spectrum Inhibition of Human Immunodeficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140

    Alexandra Trkola;Thomas J. Ketas;Kirsten A. Nagashima;Lu Zhao

  • Differential Inhibition of Human Immunodeficiency Virus Type 1 Fusion, gp120 Binding, and CC-Chemokine Activity by Monoclonal Antibodies to CCR5

    William C. Olson;Gwénaël E. E. Rabut;Kirsten A. Nagashima;Diep N. H. Tran

  • Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry

    Tatjana Dragic;Alexandra Trkola;Steven W. Lin;Kirsten A. Nagashima

  • L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus

    Emmanuel G. Cormier;Robert J. Durso;Fotini Tsamis;Lise Boussemart

  • The CCR5 and CXCR4 Coreceptors Are Both Used by Human Immunodeficiency Virus Type 1 Primary Isolates from Subtype C

    Tonie Cilliers;Jabulani Nhlapo;Mia Coetzer;Dragana Orlovic

  • Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120.

    Emmanuel G. Cormier;Marjan Persuh;Daniah A. D. Thompson;Steven W. Lin

  • Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

    Kristen E. Pascal;Christopher M. Coleman;Alejandro O. Mujica;Vishal Kamat

  • Enhancing the Proteolytic Maturation of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

    James M. Binley;Rogier W. Sanders;Rogier W. Sanders;Aditi Master;Charmagne S. Cayanan

  • Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.

    J. M. Orengo;A. R. Radin;V. Kamat;A. Badithe

  • Opportunities for therapeutic antibodies directed at G-protein-coupled receptors

    Catherine J. Hutchings;Markus Koglin;William C. Olson;Fiona H. Marshall

  • HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells.

    Meimei Shan;Per Johan Klasse;Kaustuv Banerjee;Antu K Dey

  • Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

    Audray Harris;Mario J Borgnia;Dan Shi;Alberto Bartesaghi

  • Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults

    Jeffrey M. Jacobson;Israel Lowy;Courtney V. Fletcher;Tobias J. O'Neill

Frequent Co-Authors

Paul J. Maddon
Paul J. Maddon Columbia University
John P. Moore
John P. Moore Cornell University
Andrew J. Murphy
Andrew J. Murphy St. Jude Children's Research Hospital
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Peter W. Mason
Peter W. Mason Novartis (Switzerland)
George D. Yancopoulos
George D. Yancopoulos Regeneron (United States)
James M. Binley
James M. Binley Aaron Diamond AIDS Research Center
Thomas J. Ketas
Thomas J. Ketas Cornell University
Brian Zambrowicz
Brian Zambrowicz Regeneron (United States)
Ben Berkhout
Ben Berkhout University of Amsterdam

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