World's Best Scientists 2026 revealed!

Overview

Thomas J. Ketas is affiliated with Cornell University in the United States. Their research spans key areas within the fields of Medicine and Immunology and Microbiology, with a focus on Infectious Diseases, Virology, Immunology, Epidemiology, and Oncology. The scientist's main research topics include HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Monoclonal and Polyclonal Antibodies Research, Immune Cell Function and Interaction, SARS-CoV-2 detection and testing, and Immunotherapy and Immune Responses.

Among their recent publications are:

  • "T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers" (2020, Nature Medicine)
  • "Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva" (2021, Pathogens and Immunity)
  • "Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens" (2020, PLoS Pathogens)
  • "Predictors of Nonseroconversion after SARS-CoV-2 Infection" (2021, Emerging infectious diseases)
  • "Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva" (2021, bioRxiv [Cold Spring Harbor Laboratory])

Thomas J. Ketas has collaborated frequently with several researchers, including John P. Moore, Per Johan Klasse, Andrew B. Ward, Anila Yasmeen, and Zhen Zhao.

The scientist's publications have appeared in venues such as bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, PubMed, Nature Medicine, and Pathogens and Immunity.

Best Publications

  • A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

    Rogier W. Sanders;Rogier W. Sanders;Ronald Derking;Albert Cupo;Jean-Philippe Julien

  • Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120

    Ronald S. Veazey;Robin J. Shattock;Melissa Pope;J. Christian Kirijan

  • HIV-1 neutralizing antibodies induced by native-like envelope trimers

    Rogier W. Sanders;Rogier W. Sanders;Marit J. Van Gils;Ronald Derking;Devin Sok;Devin Sok

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  • HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use

    Alexandra Trkola;Shawn E. Kuhmann;Julie M. Strizki;Elizabeth Maxwell

  • Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.

    Ronald S. Veazey;Per Johan Klasse;Susan M. Schader;Qinxue Hu

  • Potent, Broad-Spectrum Inhibition of Human Immunodeficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140

    Alexandra Trkola;Thomas J. Ketas;Kirsten A. Nagashima;Lu Zhao

  • HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

    Weifeng Xu;Paul A Santini;John S Sullivan;Bing He

  • Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers

    W. Seth Horne;Lisa M. Johnson;Thomas J. Ketas;Per Johan Klasse

  • Analysis of the Mechanism by Which the Small-Molecule CCR5 Antagonists SCH-351125 and SCH-350581 Inhibit Human Immunodeficiency Virus Type 1 Entry

    Fotini Tsamis;Svetlana Gavrilov;Francis Kajumo;Christoph Seibert

  • HIV-1–specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy

    Gabriel M. Ortiz;Douglas F. Nixon;Alexandra Trkola;James Binley

  • A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

    Pavel Pugach;Gabriel Ozorowski;Albert Cupo;Rajesh Ringe

  • The CCR5 and CXCR4 Coreceptors Are Both Used by Human Immunodeficiency Virus Type 1 Primary Isolates from Subtype C

    Tonie Cilliers;Jabulani Nhlapo;Mia Coetzer;Dragana Orlovic

  • HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

    Pavel Pugach;Andre J. Marozsan;Thomas J. Ketas;Elissa L. Landes

  • Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

    Paolo Ingallinella;Elisabetta Bianchi;Neal A. Ladwa;Ying-Jie Wang

  • Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults

    Jeffrey M. Jacobson;Israel Lowy;Courtney V. Fletcher;Tobias J. O'Neill

  • Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.

    Philip J. M. Brouwer;Aleksandar Antanasijevic;Zachary Berndsen;Anila Yasmeen

  • Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.

    Ronald S. Veazey;Thomas J. Ketas;Jason Dufour;Terri Moroney-Rasmussen

  • Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.

    Ronald S. Veazey;Per Johan Klasse;Thomas J. Ketas;Jacqueline D. Reeves

  • Evaluating the Immunogenicity of a Disulfide-Stabilized, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1

    Simon Beddows;Norbert Schülke;Marc Kirschner;Kelly Barnes

Frequent Co-Authors

Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Max Crispin
Max Crispin University of Southampton
Celia C. LaBranche
Celia C. LaBranche Duke University
William C. Olson
William C. Olson Regeneron (United States)
Marit J. van Gils
Marit J. van Gils University of Amsterdam
Jesse D. Bloom
Jesse D. Bloom Fred Hutchinson Cancer Research Center
Jean-Philippe Julien
Jean-Philippe Julien University of Toronto
Paul D. Bieniasz
Paul D. Bieniasz Rockefeller University
Stephen Baker
Stephen Baker Agency for Science, Technology and Research
Beatrice H. Hahn
Beatrice H. Hahn University of Pennsylvania

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