2026 James G. Patton: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	51	2474	2233	1220	1090	108	15300

Research.com Recognitions

2013 - Fellow of the American Association for the Advancement of Science (AAAS)
1986 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James G. Patton is affiliated with Vanderbilt University in the United States. Their primary research focus lies within the broad field of Biochemistry, Genetics, and Molecular Biology with 66 publications, concentrating significantly on Molecular Biology, Cancer Research, Physiology, and Immunology.

The scientist's research topics cover a variety of areas related to RNA biology and disease mechanisms. Key topics include:

MicroRNA in disease regulation
Extracellular vesicles in disease
RNA Research and Splicing
RNA modifications and cancer
Cancer-related molecular mechanisms research
Circular RNAs in diseases
Retinal Development and Disorders

Notable recent publications include:

"Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression," 2022, Molecular Cancer
"VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites," 2022, Developmental Cell
"Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells," 2020, Scientific Reports
"miRNAs and Müller Glia Reprogramming During Retina Regeneration," 2021, Frontiers in Cell and Developmental Biology
"Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences," 2021, Heliyon

Frequent coauthors include Robert J. Coffey, Alissa M. Weaver, Jeffrey L. Franklin, Kasey C. Vickers, and Gregory Konar.

Patton has published multiple papers in venues such as bioRxiv (Cold Spring Harbor Laboratory) with seven publications, Experimental Eye Research with two publications, and single publications in Molecular Cancer, Developmental Cell, and Scientific Reports.

Over the course of their career, the scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in both 1986 and 2013.

Best Publications

Reassessment of Exosome Composition

Dennis K. Jeppesen;Aidan M. Fenix;Jeffrey L. Franklin;James N. Higginbotham

2300
Citations
Alternative splicing in the control of gene expression

Christopher W. J. Smith;James G. Patton;Bernardo Nadal-Ginard

885
Citations
Cloning and domain structure of the mammalian splicing factor U2AF

Phillip D. Zamore;James G. Patton;Michael R. Green

725
Citations
Cloning and characterization of PSF, a novel pre-mRNA splicing factor.

J G Patton;E B Porro;J Galceran;P Tempst

467
Citations
Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing.

James G. Patton;Stephen A. Mayer;Paul Tempst;Bernardo Nadal-Ginard

456
Citations
Dynamic Sorting of Nuclear Components into Distinct Nucleolar Caps during Transcriptional Inhibition

Yaron Shav-Tal;Janna Blechman;Xavier Darzacq;Cristina Montagna

420
Citations
KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

Andrew J. McKenzie;Daisuke Hoshino;Nan Hyung Hong;Diana J. Cha

408
Citations
siRNA therapeutics: big potential from small RNAs

R C C Ryther;A S Flynt;J A Phillips;J G Patton

406
Citations
Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate

Alex S Flynt;Nan Li;Elizabeth J Thatcher;Lilianna Solnica-Krezel

374
Citations
Genomic organization of microRNAs.

Abigail F. Olena;James G. Patton

366
Citations
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Yuanyuan Lu;Xiaodi Zhao;Xiaodi Zhao;Qi Liu;Cunxi Li

355
Citations
KRAS-dependent sorting of miRNA to exosomes

Diana J Cha;Jeffrey L Franklin;Yongchao Dou;Qi Liu

349
Citations
Scanning from an independently specified branch point defines the 3' splice site of mammalian introns

Christopher W. J. Smith;Elena B. Porro;James G. Patton;Bernardo Nadal-Ginard

341
Citations
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes.

Yongchao Dou;Diana J. Cha;Jeffrey L. Franklin;James N. Higginbotham

312
Citations
Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA.

A Kaminski;S L Hunt;J G Patton;R J Jackson

312
Citations
Mutation of PTB binding sites causes misregulation of alternative 3' splice site selection in vivo.

I Pérez;C H Lin;J G McAfee;J G Patton

302
Citations
A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction.

Or Gozani;J. G. Patton;R. Reed

282
Citations
Regulation of alternative 3' splice site selection by constitutive splicing factors.

C H Lin;J G Patton

249
Citations
Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein.

Ismael Pérez;James G. McAfee;James G. Patton

226
Citations
Functional analysis of the polypyrimidine tract in pre-mRNA splicing

Candace J. Coolidge;Raymond J. Seely;James G. Patton

216
Citations

Frequent Co-Authors

Robert J. Coffey Vanderbilt University Medical Center

Alissa M. Weaver Vanderbilt University

John A. Phillips Vanderbilt University Medical Center

Bing Zhang Baylor College of Medicine

Shawn Levy Vanderbilt University

Juan J. Badimon Icahn School of Medicine at Mount Sinai

David R. Hyde University of Notre Dame

Richard M. Peek Vanderbilt University Medical Center

Bing Zhang University of Nevada, Las Vegas

Andrew J. Link Vanderbilt University

External Links

Personal website of James G. Patton

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