World's Best Scientists 2026 revealed!
Xiang-Dong Fu

Xiang-Dong Fu

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Molecular Biology
China
2026

D-Index & Metrics

Molecular Biology

D-Index
112
Citations
45431
World Ranking
343
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in China Leader Award
  • 2025 - Research.com Molecular Biology in China Leader Award
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Xiang-Dong Fu is affiliated with Westlake University in China. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology, Plant Science, Genetics, Cancer Research, and Epidemiology.

The main topics covered by their work include RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, CRISPR and Genetic Engineering, Genomics and Chromatin Dynamics, RNA regulation and disease, and cancer-related molecular mechanisms research.

Several scientific journals and publication venues have featured multiple works by Xiang-Dong Fu. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature Communications, Cell Research, and Blood Advances.

The scientist has collaborated extensively with several co-authors over their career. Frequent co-authors are Yajing Hao, Changwei Shao, Zhengyu Liang, Dong-Er Zhang, and Jiayu Chen.

Xiang-Dong Fu has authored or co-authored numerous research papers. Key publications include:

  • A large-scale binding and functional map of human RNA-binding proteins (2020, Nature)
  • Reversing a model of Parkinson's disease with in situ converted nigral neurons (2020, Nature)
  • Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins (2020, Genome Biology)
  • TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS (2021, Nature Structural & Molecular Biology)
  • LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs (2022, Science)

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2010.

Best Publications

  • The ENCODE (ENCyclopedia of DNA elements) Project

    E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

  • Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

    Fa Xing Yu;Bin Zhao;Nattapon Panupinthu;Jenna L. Jewell

  • Context-dependent control of alternative splicing by RNA-binding proteins

    Xiang-Dong Fu;Manuel Ares

  • A large-scale binding and functional map of human RNA-binding proteins

    Eric L. Van Nostrand;Peter Freese;Gabriel A. Pratt;Xiaofeng Wang

  • The superfamily of arginine/serine-rich splicing factors.

    X D Fu

  • Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

    Dong Wang;Ivan Garcia-Bassets;Chris Benner;Wenbo Li

  • Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

    Xiang-Dong Fu;Tom Maniatis

  • 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

    Olivier Harismendy;Dimple Notani;Xiaoyuan Song;Nazli G. Rahim

  • A serine kinase regulates intracellular localization of splicing factors in the cell cycle.

    Jian-fang Gui;William S.Lane;Xiang-dong Fu

  • Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

    Chunru Lin;Liuqing Yang;Bogdan Tanasa;Bogdan Tanasa;Kasey Hutt

  • An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

    Gene W Yeo;Nicole G Coufal;Tiffany Y Liang;Tiffany Y Liang;Grace E Peng

  • Opposing LSD1 complexes function in developmental gene activation and repression programmes

    Jianxun Wang;Kathleen Scully;Xiaoyan Zhu;Ling Cai

  • Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration

    Clotilde Lagier-Tourenne;Michael Baughn;Frank Rigo;Shuying Sun

  • Associations between distinct pre-mRNA splicing components and the cell nucleus.

    D. L. Spector;Xiang-Dong Fu;T. Maniatis

  • Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated microRNA Circuits

    Yuanchao Xue;Kunfu Ouyang;Jie Huang;Yu Zhou;Yu Zhou

  • Timing of plant immune responses by a central circadian regulator.

    Wei Wang;Jinyoung Yang Barnaby;Jinyoung Yang Barnaby;Yasuomi Tada;Yasuomi Tada;Hairi Li

  • Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

    Yuanchao Xue;Yu Zhou;Yu Zhou;Tongbin Wu;Tuo Zhu

  • Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.

    Ivan Garcia-Bassets;Young-Soo Kwon;Francesca Telese;Gratien G. Prefontaine

  • Regulation of Splicing by SR proteins and SR Protein-Specific Kinases

    Zhihong Zhou;Xiang-Dong Fu

  • MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation

    Xiaorong Zhang;Xinxin Zuo;Bo Yang;Zongran Li

Frequent Co-Authors

Michael G. Rosenfeld
Michael G. Rosenfeld University of California, San Diego
Gene W. Yeo
Gene W. Yeo University of California, San Diego
Gourisankar Ghosh
Gourisankar Ghosh University of California, San Diego
Dong-Er Zhang
Dong-Er Zhang University of California, San Diego
Dong Wang
Dong Wang Peking University
Christopher K. Glass
Christopher K. Glass University of California, San Diego
Kang Zhang
Kang Zhang Macau University of Science and Technology
Don W. Cleveland
Don W. Cleveland University of California, San Diego
Ju Chen
Ju Chen University of California, San Diego
Brenton R. Graveley
Brenton R. Graveley University of Connecticut Health Center

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