2026 David L. Spector: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	100	525	469	291	255	245	46785

Research.com Recognitions

2014 - Fellow of the American Academy of Arts and Sciences

Overview

David L. Spector is affiliated with Cold Spring Harbor Laboratory in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cancer Research, Surgery, Immunology, and Oncology.

The scientist's work covers several main topics including RNA Research and Splicing, Cancer-related molecular mechanisms research, RNA modifications and cancer, Cancer Genomics and Diagnostics, Bariatric Surgery and Outcomes, Immune cells in cancer, and Genomics and Phylogenetic Studies.

Among their recent papers are:

Long non-coding RNAs: definitions, functions, challenges and recommendations (2023, Nature Reviews Molecular Cell Biology)
Activating a collaborative innate-adaptive immune response to control metastasis (2021, Cancer Cell)
MALAT1 Long Non-Coding RNA: Functional Implications (2020, Non-Coding RNA)
Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation (2023, Cancer Cell)
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment (2024, Cancer Cell)

Frequent co-authors of David L. Spector include:

Sonam Bhatia
David A. Tuveson
Bodu Liu
Suzanne Russo
John E. Wilkinson

The scientist has contributed publications to several venues, notably:

bioRxiv (Cold Spring Harbor Laboratory)
Cancer Research
Cancer Cell
Nature Communications
Surgical Endoscopy

David L. Spector was named a Fellow of the American Academy of Arts and Sciences in 2014.

Best Publications

Long noncoding RNAs: functional surprises from the RNA world

Jeremy E. Wilusz;Hongjae Sunwoo;David L. Spector

2619
Citations
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.

Masashi Narita;Sabrina Nuñez;Sabrina Nuñez;Edith Heard;Masako Narita

2597
Citations
The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Tony Gutschner;Monika Hämmerle;Moritz Eißmann;Jeff Hsu

1681
Citations
Nuclear speckles: a model for nuclear organelles.

Angus I. Lamond;David L. Spector

1204
Citations
Cells: a laboratory manual

David L. Spector;Robert D. Goldman;Leslie A. Leinwand

874
Citations
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.

Delphine Bernard;Kannanganattu V Prasanth;Kannanganattu V Prasanth;Vidisha Tripathi;Sabrina Colasse

860
Citations
From silencing to gene expression: real-time analysis in single cells.

Susan M Janicki;Toshiro Tsukamoto;Simone E Salghetti;William P Tansey

809
Citations
The dynamics of a pre-mRNA splicing factor in living cells.

Tom Misteli;Javier F. Cáceres;David L. Spector

786
Citations
3′ End Processing of a Long Nuclear-Retained Noncoding RNA Yields a tRNA-like Cytoplasmic RNA

Jeremy E. Wilusz;Susan M. Freier;David L. Spector

779
Citations
Macromolecular domains within the cell nucleus.

David L. Spector

765
Citations
Regulating Gene Expression through RNA Nuclear Retention

Kannanganattu V. Prasanth;Supriya G. Prasanth;Zhenyu Xuan;Stephen Hearn

761
Citations
Biogenesis and function of nuclear bodies

Yuntao S. Mao;Bin Zhang;David L. Spector

720
Citations
MEN ε/β nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles

Hongjae Sunwoo;Marcel E. Dinger;Jeremy E. Wilusz;Paulo P. Amaral

689
Citations
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene

Shimon Efrat;Susanne Linde;Hans Kofod;David Spector

682
Citations
Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation.

Edith Heard;Claire Rougeulle;Danielle Arnaud;Philip Avner

632
Citations
Associations between distinct pre-mRNA splicing components and the cell nucleus.

D. L. Spector;Xiang-Dong Fu;T. Maniatis

631
Citations
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult.

Bin Zhang;Gayatri Arun;Yuntao S. Mao;Zsolt Lazar

630
Citations
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

Nadya Dimitrova;Yi-Chun M. Chen;David L. Spector;Titia de Lange

628
Citations
Identification of Nuclear Dicing Bodies Containing Proteins for MicroRNA Biogenesis in Living Arabidopsis Plants

Yuda Fang;David L. Spector

619
Citations
Applications of the green fluorescent protein in cell biology and biotechnology

Tom Misteli;David L. Spector

590
Citations

Frequent Co-Authors

Robert D. Goldman Northwestern University

Kannanganattu V. Prasanth University of Illinois at Urbana-Champaign

Roland Eils Charité - University Medicine Berlin

Frank Rigo Ionis Pharmaceuticals (United States)

Adrian R. Krainer Cold Spring Harbor Laboratory

C. Frank Bennett Ionis Pharmaceuticals (United States)

Mark H. Ellisman University of California, San Diego

Leslie A. Leinwand University of Colorado Boulder

Tom Misteli National Institutes of Health

Edith Heard Collège de France

External Links

Personal website of David L. Spector

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